Development Level

Tbio 19 | 11,445
Tchem 9 | 1,598
Tdark 9 | 6,588
Tclin 2 | 613

IMPC Phenotype

male infertility 2 | 123
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased mature B cell number 1 | 7
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased lean body mass 1 | 172
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 22 | 8,520
Carcinoma 13 | 11,493
Rheumatoid arthritis 11 | 1,191
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 8 | 6,241
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
Prevention of Cardiac Transplant Rejection 7 | 15
Prevention of Kidney Transplant Rejection 7 | 17
Prevention of Liver Transplant Rejection 7 | 15
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
malignant mesothelioma 7 | 3,232
Breast cancer 6 | 3,578
Cancer 6 | 2,499
acute quadriplegic myopathy 6 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Keratoconjunctivitis sicca 5 | 25
Severe Recalcitrant Psoriasis 5 | 12
Tear film insufficiency 5 | 15
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Stomach Neoplasms 4 | 300
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Intractable Eczema 3 | 5
Liver transplant rejection 3 | 5
Prevention of Transplant Rejection 3 | 6
Pulmonary lymphangioleiomyomatosis 3 | 5
Renal Cell Carcinoma 3 | 214
Renal transplant rejection 3 | 13
Transplanted organ rejection 3 | 10
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
post-traumatic stress disorder 3 | 40
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Bruck syndrome 2 | 10
Dentinogenesis imperfecta 2 | 25
Disease Progression 2 | 136
Duchenne muscular dystrophy 2 | 601
Kidney cancer 2 | 2,613
Major Depressive Disorder 2 | 301
Multiple myeloma 2 | 1,332
Osteogenesis imperfecta 2 | 34
Osteogenesis imperfecta type III (disorder) 2 | 11
Osteogenesis imperfecta type IV (disorder) 2 | 10
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
Vascular disease 2 | 319
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
lung carcinoma 2 | 2,843
osteogenesis imperfecta type 3 2 | 11
osteogenesis imperfecta type 4 2 | 10
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Acquired immunodeficiency syndrome 1 | 197
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 1 | 3
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Chromosome 17q12 deletion syndrome 1 | 16
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 1 | 3
Hypohidrotic ectodermal dysplasia 1 | 15

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Female tissues 36 | 17,400
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Liver and Pancreas 35 | 16,750
Respiratory system 35 | 16,393
Male tissues 34 | 17,142
Urinary Tract 34 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Enzyme 38 | 4,145
Non-IDG 1 | 12,091

GO Function

peptidyl-prolyl cis-trans isom... 39 | 39
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peptidyl-prolyl cis-trans isomerase CWC27 homolog CWC27 Tbio Enzyme -0.57161 3.71 84
Peptidyl-prolyl cis-trans isomerase FKBP8 FKBP8 Tbio Enzyme -1.61406 49.5 282
Peptidyl-prolyl cis-trans isomerase-like 2 PPIL2 Tbio Enzyme -0.99815 8.89 146
Peptidyl-prolyl cis-trans isomerase E PPIE Tbio Enzyme -1.36546 21.0 185
Peptidyl-prolyl cis-trans isomerase-like 3 PPIL3 Tbio Enzyme -0.91842 8.27 154
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 FKBP6 Tbio Enzyme -1.27085 19.8 174
Serine/threonine-protein phosphatase 2A activator PTPA Tchem Enzyme -3.25782 1802.5 255
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 PIN4 Tbio Enzyme -1.76231 53.3 127
Peptidyl-prolyl cis-trans isomerase FKBP9 FKBP9 Tdark Enzyme -0.39782 3.17 58