Development Level

Tbio 85 | 10,625
Tchem 27 | 1,890
Tdark 12 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 11 | 633
embryonic lethality prior to t... 4 | 187
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased circulating choleste... 3 | 53
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
prenatal lethality prior to he... 3 | 64
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
decreased bone mineral density 2 | 126
decreased grip strength 2 | 123
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to o... 2 | 148
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
increased total body fat amoun... 2 | 57
abnormal body wall morphology 1 | 7
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal vertebrae morphology 1 | 14
abnormal zygomatic bone morpho... 1 | 3
aorta dilation 1 | 3
decreased CD8-positive, alpha-... 1 | 26
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased brain size 1 | 4
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased red blood cell distr... 1 | 11
edema 1 | 11
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hemorrhage 1 | 12
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating chloride... 1 | 43
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased red blood cell distr... 1 | 21
increased thermal nociceptive ... 1 | 9
prenatal lethality 1 | 16
protruding tongue 1 | 1
short tibia 1 | 82
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

ovarian cancer 86 | 8,484
glioblastoma 68 | 5,572
medulloblastoma, large-cell 64 | 6,234
osteosarcoma 64 | 7,933
psoriasis 53 | 6,685
lung cancer 50 | 4,466
atypical teratoid / rhabdoid tumor 49 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,289
primitive neuroectodermal tumor 44 | 3,031
Breast cancer 41 | 3,094
invasive ductal carcinoma 41 | 2,950
pediatric high grade glioma 39 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
Cancer 34 | 2,346
pancreatic cancer 34 | 2,300
non-small cell lung cancer 33 | 2,798
malignant mesothelioma 32 | 3,162
lung adenocarcinoma 31 | 2,713
group 3 medulloblastoma 30 | 2,254
pilocytic astrocytoma 30 | 3,086
adrenocortical carcinoma 28 | 1,427
breast carcinoma 27 | 1,614
colon cancer 27 | 1,475
ductal carcinoma in situ 26 | 1,745
oligodendroglioma 25 | 2,849
Carcinoma 24 | 2,147
posterior fossa group A ependymoma 22 | 1,511
Atopic dermatitis 21 | 944
Endometriosis 21 | 535
Multiple myeloma 21 | 1,327
astrocytic glioma 18 | 2,241
subependymal giant cell astrocytoma 18 | 2,287
adult high grade glioma 17 | 2,148
interstitial cystitis 17 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
nasopharyngeal carcinoma 17 | 1,056
sonic hedgehog group medulloblastoma 17 | 1,482
ulcerative colitis 17 | 2,087
IGA Glomerulonephritis 16 | 454
lung carcinoma 16 | 2,844
Pick disease 15 | 1,893
ependymoma 15 | 2,514
Waldenstrons macroglobulinemia 14 | 765
astrocytoma 14 | 1,493
medulloblastoma 14 | 1,524
primary pancreatic ductal adenocarcinoma 14 | 1,271
group 4 medulloblastoma 13 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Rheumatoid Arthritis 12 | 1,160
acute quadriplegic myopathy 12 | 1,157
atypical teratoid/rhabdoid tumor 12 | 1,095
diabetes mellitus 12 | 1,663
posterior fossa group B ependymoma 12 | 1,530
primary Sjogren syndrome 11 | 789
tuberculosis 11 | 1,557
esophageal adenocarcinoma 10 | 737
juvenile dermatomyositis 10 | 1,189
progressive supranuclear palsy 10 | 674
non primary Sjogren syndrome sicca 9 | 840
dermatomyositis 8 | 933
pituitary cancer 8 | 1,972
Duchenne muscular dystrophy 7 | 602
Mammary Neoplasms 7 | 410
active Crohn's disease 7 | 918
hereditary spastic paraplegia 7 | 313
spina bifida 7 | 1,064
tuberculosis and treatment for 6 months 7 | 686
Down syndrome 6 | 548
Intellectual disability 6 | 573
Neurodegenerative disease 6 | 383
Retinitis pigmentosa 6 | 153
Vascular disease 6 | 281
gastric carcinoma 6 | 832
Amyotrophic Lateral Sclerosis 5 | 431
Microcephaly 5 | 149
Parkinson's disease 5 | 364
Polycystic Ovary Syndrome 5 | 332
Renal Cell Carcinoma 5 | 199
aldosterone-producing adenoma 5 | 664
cutaneous lupus erythematosus 5 | 1,056
hepatocellular carcinoma 5 | 532
inflammatory breast cancer 5 | 404
Alzheimer's disease 4 | 644
Animal Mammary Neoplasms 4 | 136
Liver carcinoma 4 | 217
Mammary Neoplasms, Experimental 4 | 150
Neuropathy 4 | 210
Prostatic Neoplasms 4 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cystic fibrosis 4 | 1,665
fibroadenoma 4 | 557
ovarian neoplasm 4 | 97
Male infertility 3 | 170
Obesity 3 | 616
Paraplegia 3 | 71
Type 2 diabetes mellitus 3 | 189
acute myeloid leukemia 3 | 780
mucosa-associated lymphoid tissue lymphoma 3 | 480
non-small cell lung carcinoma 3 | 413
pancreatic carcinoma 3 | 567

Tissue

Blood and immune system 125 | 17,995
Cardiovascular System 125 | 17,958
Digestive Tract 125 | 18,473
Endocrine System 125 | 18,512
Female tissues 125 | 18,647
Liver and Pancreas 125 | 18,136
Male tissues 125 | 17,969
Nervous System 125 | 18,561
Respiratory system 125 | 17,484
Skin and soft tissues 125 | 18,115
Urinary Tract 125 | 18,444

Target Family

Non-IDG 85 | 11,971
Enzyme 26 | 4,146
Kinase 11 | 634
Epigenetic 1 | 242
Ion Channel 1 | 341
Transporter 1 | 473

GO Component

midbody 125 | 125
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 55 kDa CEP55 Tbio Non-IDG -1.36694 32.7 163
ADP-ribosylation factor 6 ARF6 Tchem Enzyme -2.45898 333.2 252
Aurora kinase C AURKC Tchem Kinase -1.96390 96.7 285
Saccharopine dehydrogenase-like oxidoreductase SCCPDH Tbio Enzyme -0.97062 6.25 83
Tetratricopeptide repeat protein 19, mitochondrial TTC19 Tbio Non-IDG -0.92140 9.50 28
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.65484 47.3 120
Receptor of activated protein C kinase 1 RACK1 Tbio Non-IDG -2.55353 408.6 282
Ras-GEF domain-containing family member 1B RASGEF1B Tdark Non-IDG -0.67644 5.25 36
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 Tchem Enzyme 515.3 475
Zinc finger protein 330 ZNF330 Tdark Non-IDG -0.39794 3.06 15