Development Level

Tbio 99 | 11,445
Tdark 15 | 6,588
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 3 | 239
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
short tibia 1 | 97

Disease

ovarian cancer 47 | 8,520
lung cancer 44 | 4,740
Carcinoma 37 | 11,493
osteosarcoma 34 | 7,950
medulloblastoma, large-cell 31 | 6,241
diabetes mellitus 27 | 1,728
Multiple myeloma 24 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
Diamond-Blackfan anemia 20 | 31
glioblastoma 20 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
psoriasis 19 | 6,694
Cancer 17 | 2,499
Anemia 14 | 365
Waldenstrons macroglobulinemia 14 | 765
acute quadriplegic myopathy 14 | 1,158
malignant mesothelioma 14 | 3,232
oligodendroglioma 14 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Breast cancer 12 | 3,578
group 3 medulloblastoma 12 | 4,104
sonic hedgehog group medulloblastoma 12 | 467
Fatigue 11 | 182
Pallor 11 | 40
non-small cell lung cancer 11 | 2,890
Abnormality of the urinary system 10 | 21
Anemia, Diamond-Blackfan 10 | 16
Anemia, Macrocytic 10 | 18
Cardiac Arrhythmia 10 | 103
Cardiac conduction abnormalities 10 | 78
Cleft Palate 10 | 271
Conduction disorder of the heart 10 | 79
Delayed Puberty 10 | 97
EKG abnormalities 10 | 78
Electrocardiogram abnormal 10 | 81
Electrocardiogram change 10 | 78
Hand deformities 10 | 32
Intermittent migraine headaches 10 | 68
Migraine Disorders 10 | 76
Uranostaphyloschisis 10 | 167
acute myeloid leukemia 10 | 783
astrocytoma 10 | 1,146
colon cancer 10 | 1,478
cystic fibrosis 10 | 1,696
ependymoma 10 | 4,679
genital abnormal 10 | 17
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
reproductive system abnormality 10 | 17
subependymal giant cell astrocytoma 10 | 2,287
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Stomach Neoplasms 8 | 300
adult high grade glioma 8 | 3,801
lung adenocarcinoma 8 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Astrocytoma, Pilocytic 7 | 3,081
Disease Progression 7 | 136
Intellectual disability 7 | 1,016
astrocytic glioma 7 | 2,597
primitive neuroectodermal tumor 7 | 3,035
Adenocarcinoma of lung 6 | 142
Disease Models, Animal 6 | 155
Short stature 6 | 531
invasive ductal carcinoma 6 | 2,951
mucosa-associated lymphoid tissue lymphoma 6 | 484
pancreatic cancer 6 | 2,398
group 4 medulloblastoma 5 | 1,855
Animal Mammary Neoplasms 4 | 136
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Downward slant of palpebral fissure 4 | 158
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Global developmental delay 4 | 608
Hemoglobin low 4 | 124
Infantile onset 4 | 238
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
Mental and motor retardation 4 | 608
Reticulocytopenia 4 | 10
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Shwachman-Diamond syndrome 4 | 17
Small head 4 | 374
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
dermatomyositis 4 | 966
hereditary spastic paraplegia 4 | 318
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Hepatomegaly 3 | 285
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
lung carcinoma 3 | 2,843
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 114 | 18,159
Male tissues 113 | 17,142
Skin and soft tissues 113 | 17,230
Blood and immune system 112 | 16,909
Digestive Tract 112 | 17,369
Female tissues 112 | 17,400
Liver and Pancreas 112 | 16,750
Nervous System 112 | 16,725
Respiratory system 112 | 16,393
Cardiovascular System 111 | 15,192
Urinary Tract 111 | 16,678

Target Family

Non-IDG 111 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Cytosolic ribosome 120 | 120
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363