Development Level

Tbio 177 | 11,445
Tchem 39 | 1,598
Tclin 24 | 613
Tdark 22 | 6,588

Collection

GPCR: IDG Consortium (Complete... 4 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 10 | 298
preweaning lethality, incomple... 9 | 499
abnormal embryo size 6 | 220
decreased vertical activity 6 | 208
enlarged heart 6 | 210
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
increased heart weight 5 | 62
abnormal seminal vesicle morph... 4 | 114
embryonic growth retardation 4 | 106
increased bone mineral content 4 | 108
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
abnormal retina morphology 3 | 71
decreased body length 3 | 101
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased grip strength 3 | 116
enlarged spleen 3 | 41
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
pallor 3 | 34
abnormal coat appearance 2 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal ear morphology 2 | 9
abnormal femur morphology 2 | 14
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal pericardium morpholog... 2 | 26
abnormal skin morphology 2 | 50
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased cardiac muscle contr... 2 | 11
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased heart rate 2 | 18
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
dilated heart left ventricle 2 | 11
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
male infertility 2 | 123
pale yolk sac 2 | 25
persistence of hyaloid vascula... 2 | 33
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal somite shape 1 | 5
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vitelline vasculature... 1 | 6
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased exploration in new e... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
polycystic kidney 1 | 15
premature death 1 | 5
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 202 | 11,493
ovarian cancer 173 | 8,520
glioblastoma 147 | 5,792
osteosarcoma 132 | 7,950
Cancer 118 | 2,499
psoriasis 116 | 6,694
ependymoma 115 | 4,679
medulloblastoma, large-cell 115 | 6,241
atypical teratoid / rhabdoid tumor 114 | 5,112
lung cancer 106 | 4,740
malignant mesothelioma 105 | 3,232
lung carcinoma 101 | 2,843
Breast cancer 98 | 3,578
Astrocytoma, Pilocytic 92 | 3,081
invasive ductal carcinoma 88 | 2,951
pancreatic cancer 88 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 85 | 2,955
adult high grade glioma 82 | 3,801
non-small cell lung cancer 82 | 2,890
lung adenocarcinoma 79 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 78 | 3,291
oligodendroglioma 76 | 2,850
group 3 medulloblastoma 71 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 71 | 2,989
Kidney cancer 66 | 2,613
interstitial cystitis 64 | 2,312
subependymal giant cell astrocytoma 62 | 2,287
ulcerative colitis 62 | 1,819
primitive neuroectodermal tumor 61 | 3,035
ductal carcinoma in situ 58 | 1,745
cystic fibrosis 57 | 1,696
astrocytic glioma 55 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 54 | 1,962
tuberculosis 54 | 2,010
primary pancreatic ductal adenocarcinoma 53 | 1,109
diabetes mellitus 52 | 1,728
breast carcinoma 51 | 1,638
juvenile dermatomyositis 50 | 1,187
pituitary cancer 47 | 1,972
gastric carcinoma 45 | 807
adrenocortical carcinoma 41 | 1,428
astrocytoma 40 | 1,146
group 4 medulloblastoma 39 | 1,855
colon cancer 38 | 1,478
Pick disease 37 | 1,894
acute quadriplegic myopathy 37 | 1,158
esophageal adenocarcinoma 37 | 737
Autosomal recessive predisposition 36 | 1,442
Duchenne muscular dystrophy 35 | 601
dermatomyositis 35 | 966
Rheumatoid arthritis 34 | 1,191
nasopharyngeal carcinoma 32 | 1,058
pediatric high grade glioma 32 | 1,064
Alzheimer's disease 29 | 658
Schizophrenia 29 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 29 | 510
Liver Cirrhosis, Experimental 28 | 769
active Crohn's disease 28 | 922
Multiple Sclerosis 27 | 540
Multiple myeloma 26 | 1,332
cutaneous lupus erythematosus 25 | 1,057
Atopic dermatitis 24 | 952
Breast Neoplasms 24 | 445
spina bifida 24 | 1,074
Mammary Neoplasms 23 | 425
active ulcerative colitis 23 | 764
Hypersensitivity reaction type II disease 22 | 253
Endometriosis 21 | 540
Kidney disease 21 | 430
aldosterone-producing adenoma 21 | 665
Prostatic Neoplasms 19 | 495
fibroadenoma 19 | 559
Anemia 18 | 365
Down syndrome 18 | 499
Liver cancer 18 | 604
Neoplasm Invasiveness 18 | 161
Arthritis 17 | 290
Barrett's esophagus 17 | 182
Hypertension 17 | 396
Liver disease 17 | 237
interstitial lung disease 17 | 298
primary Sjogren syndrome 17 | 735
Atherosclerosis 16 | 291
Vascular disease 16 | 319
acute myeloid leukemia 16 | 783
mucosa-associated lymphoid tissue lymphoma 16 | 484
non primary Sjogren syndrome sicca 16 | 891
Becker muscular dystrophy 15 | 191
Melanoma 15 | 711
Stomach Neoplasms 15 | 300
Waldenstrons macroglobulinemia 15 | 765
medulloblastoma 15 | 720
non-small cell lung carcinoma 15 | 317
progressive supranuclear palsy 15 | 676
urothelial carcinoma 15 | 318
Hypertensive disease 14 | 292
Neoplasm Metastasis 14 | 168
Obesity 14 | 678
head and neck cancer 14 | 271
posterior fossa group A ependymoma 14 | 468

Tissue

Nervous System 252 | 16,725
Endocrine System 251 | 18,159
Urinary Tract 251 | 16,678
Digestive Tract 250 | 17,369
Female tissues 250 | 17,400
Male tissues 250 | 17,142
Skin and soft tissues 250 | 17,230
Liver and Pancreas 249 | 16,750
Blood and immune system 248 | 16,909
Respiratory system 248 | 16,393
Cardiovascular System 245 | 15,192

Target Family

Non-IDG 179 | 12,091
Enzyme 34 | 4,145
Transporter 16 | 473
Kinase 15 | 634
GPCR 13 | 408
Ion Channel 3 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

ZL55 MPM 262 | 262
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
Metal transporter CNNM4 CNNM4 Tbio Non-IDG -1.18531 16.5 123
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Plexin-B2 PLXNB2 Tbio Non-IDG -1.25236 17.4 82
Bone marrow stromal antigen 2 BST2 Tbio Non-IDG -2.59753 424.5 464
LRRN4 C-terminal-like protein LRRN4CL Tdark Non-IDG 0.00000 77
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Intercellular adhesion molecule 5 ICAM5 Tbio Non-IDG -1.75978 67.3 192
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.95096 10.7 123
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 RPN1 Tbio Enzyme -2.17901 146.5 319