Development Level

Tbio 200 | 11,445
Tdark 75 | 6,588
Tchem 23 | 1,598
Tclin 11 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 21 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 5 | 278
embryonic growth retardation 4 | 106
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
enlarged heart 3 | 210
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
increased circulating total pr... 2 | 28
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating total pr... 1 | 49
decreased total body fat amoun... 1 | 207
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
short tibia 1 | 97
vertebral transformation 1 | 12

Disease

ovarian cancer 159 | 8,520
Carcinoma 117 | 11,493
osteosarcoma 106 | 7,950
lung cancer 95 | 4,740
medulloblastoma, large-cell 73 | 6,241
psoriasis 67 | 6,694
Multiple myeloma 65 | 1,332
diabetes mellitus 57 | 1,728
glioblastoma 57 | 5,792
atypical teratoid / rhabdoid tumor 53 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,291
Cancer 49 | 2,499
group 3 medulloblastoma 49 | 4,104
Breast cancer 42 | 3,578
ependymoma 38 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
non-small cell lung cancer 31 | 2,890
malignant mesothelioma 30 | 3,232
adult high grade glioma 29 | 3,801
oligodendroglioma 29 | 2,850
acute quadriplegic myopathy 28 | 1,158
Diamond-Blackfan anemia 27 | 31
Waldenstrons macroglobulinemia 26 | 765
astrocytic glioma 25 | 2,597
acute myeloid leukemia 24 | 783
lung adenocarcinoma 24 | 2,716
subependymal giant cell astrocytoma 24 | 2,287
Anemia 23 | 365
Breast Neoplasms 23 | 445
Cardiac Arrhythmia 23 | 103
Cardiac conduction abnormalities 23 | 78
Conduction disorder of the heart 23 | 79
EKG abnormalities 23 | 78
Electrocardiogram abnormal 23 | 81
Electrocardiogram change 23 | 78
Mammary Neoplasms 23 | 425
colon cancer 23 | 1,478
cystic fibrosis 22 | 1,696
Astrocytoma, Pilocytic 21 | 3,081
Fatigue 21 | 182
Intermittent migraine headaches 21 | 68
Migraine Disorders 21 | 76
invasive ductal carcinoma 21 | 2,951
primitive neuroectodermal tumor 21 | 3,035
Kidney cancer 20 | 2,613
astrocytoma 20 | 1,146
Epilepsy 19 | 792
Short stature 19 | 531
Stomach Neoplasms 19 | 300
group 4 medulloblastoma 19 | 1,855
non primary Sjogren syndrome sicca 18 | 891
pancreatic cancer 17 | 2,398
Adenocarcinoma of lung 16 | 142
Cleft Palate 16 | 271
Disease Models, Animal 16 | 155
Neurodegenerative disease 16 | 414
pediatric high grade glioma 16 | 1,064
Cerebellar Ataxia 15 | 304
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Schizophrenia 15 | 1,160
Delayed Puberty 14 | 97
Disease Progression 14 | 136
Intellectual disability 14 | 1,016
Myopathy 14 | 185
Pallor 14 | 40
Pick disease 14 | 1,894
Seizures 14 | 596
Uranostaphyloschisis 14 | 167
breast carcinoma 14 | 1,638
sonic hedgehog group medulloblastoma 14 | 467
Abnormality of the urinary system 13 | 21
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Hand deformities 13 | 32
Optic Atrophy 13 | 242
genital abnormal 13 | 17
lung carcinoma 13 | 2,843
reproductive system abnormality 13 | 17
Autosomal recessive predisposition 12 | 1,442
Dystonia 12 | 164
Leigh disease 12 | 100
Mitochondrial myopathy 12 | 26
Vascular disease 12 | 319
dermatomyositis 12 | 966
primary pancreatic ductal adenocarcinoma 12 | 1,109
Blepharoptosis 11 | 231
Cerebral atrophy 11 | 178
Dementia 11 | 175
Heart failure 11 | 162
Hypertensive disease 11 | 292
Leber hereditary optic neuropathy 11 | 14
Peripheral Neuropathy 11 | 134
Sensorineural Hearing Loss (disorder) 11 | 284
Attention deficit hyperactivity disorder 10 | 278
Prostatic Neoplasms 10 | 495
juvenile dermatomyositis 10 | 1,187

Tissue

Endocrine System 299 | 18,159
Female tissues 298 | 17,400
Skin and soft tissues 298 | 17,230
Nervous System 297 | 16,725
Blood and immune system 296 | 16,909
Digestive Tract 296 | 17,369
Male tissues 296 | 17,142
Liver and Pancreas 294 | 16,750
Urinary Tract 294 | 16,678
Respiratory system 293 | 16,393
Cardiovascular System 291 | 15,192

Target Family

Non-IDG 240 | 12,091
Enzyme 43 | 4,145
Kinase 13 | 634
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
Nuclear Receptor 1 | 48

Compartment GO Term

Ribosome 309 | 309
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability