Development Level

Tbio 18 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 2 | 239
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal joint morphology 1 | 23
brachydactyly 1 | 19
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased anti-nuclear antigen... 1 | 19
increased circulating calcium ... 1 | 34
increased circulating phosphat... 1 | 26
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
syndactyly 1 | 23

Disease

ovarian cancer 12 | 8,520
Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
Autosomal recessive predisposition 5 | 1,442
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 4 medulloblastoma 5 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Failure to gain weight 4 | 365
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
Breast cancer 3 | 3,578
Rheumatoid arthritis 3 | 1,191
Sengers syndrome 3 | 18
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Cataract 2 | 297
Chondrodysplasia punctata 2 | 41
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Epilepsy 2 | 792
Fever 2 | 138
Frontal bossing 2 | 157
Hepatomegaly 2 | 285
Hypertriglyceridemia result 2 | 37
Hypoplastic mandible condyle 2 | 275
Kidney cancer 2 | 2,613
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Lipodystrophy 2 | 40
Liver disease 2 | 237
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Muscle hypotonia 2 | 571
Muscular dystrophy 2 | 75
Myalgia 2 | 54
Myocardial Ischemia 2 | 169
Myopathy 2 | 185
Orbital separation excessive 2 | 244
Rhizomelia 2 | 25
Rhizomelic chondrodysplasia punctata 2 | 11
Schizophrenia 2 | 1,160
Seizures 2 | 596
Short upper arms 2 | 16
Small head 2 | 374
Toxic encephalopathy 2 | 141
Wide bregma sutures 2 | 46
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
non primary Sjogren syndrome sicca 2 | 891
primitive neuroectodermal tumor 2 | 3,035
Acquired immunodeficiency syndrome 1 | 197
Congenital dyserythropoietic anemia 1 | 18
Dental abnormalities 1 | 60
Dentin caries 1 | 5
Fatty liver disease 1 | 103
Fibrosis, Liver 1 | 32
Hypogonadotropic hypogonadism 1 | 89
Leigh disease 1 | 100
Metabolic acidosis 1 | 90
Pathological fracture 1 | 20
SPONDYLOCOSTAL DYSOSTOSIS 5 1 | 4
Short to absent middle phalanges 1 | 5
Tooth Abnormalities 1 | 69
X- linked recessive 1 | 110

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Enzyme 17 | 4,145
Kinase 4 | 634

WikiPathways Pathway

Glycerophospholipid Biosynthet... 21 | 21
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic GPD1 Tbio Enzyme -1.78878 59.3 225