Development Level

Tbio 34 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased body length 2 | 101
decreased red blood cell distr... 2 | 41
abnormal bone mineralization 1 | 38
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal placenta size 1 | 20
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
megacolon 1 | 2
pallor 1 | 34
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 31 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 16 | 7,950
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 13 | 5,792
Cancer 12 | 2,499
Kidney cancer 12 | 2,613
medulloblastoma, large-cell 12 | 6,241
Breast cancer 11 | 3,578
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
acute quadriplegic myopathy 8 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
psoriasis 8 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
lung cancer 7 | 4,740
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
Myopathy 6 | 185
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
juvenile dermatomyositis 6 | 1,187
primitive neuroectodermal tumor 6 | 3,035
Cleft Palate 5 | 271
Intellectual disability 5 | 1,016
Orbital separation excessive 5 | 244
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
Skin cancer 5 | 469
pancreatic cancer 5 | 2,398
tuberculosis 5 | 2,010
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Dull intelligence 4 | 645
Liver cancer 4 | 604
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Obesity 4 | 678
Poor school performance 4 | 645
Rhabdomyosarcoma 4 | 39
Uranostaphyloschisis 4 | 167
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Brachydactyly 3 | 156
Brain infarction 3 | 22
Breast Neoplasms 3 | 445
Broad flat nasal bridge 3 | 236
Convex nasal bridge 3 | 57
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Ectomesenchymoma 3 | 5
Flat face 3 | 52
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypotrophic malar bone 3 | 129
Hypotrophic maxilla 3 | 66
Lordosis 3 | 54
Malar flattening 3 | 129
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Micrognathism 3 | 275
Nasal bridge wide 3 | 236
Prominent nasal bridge 3 | 57
Prostatic Neoplasms 3 | 495
Retrusion of upper jaw bones 3 | 66
Rheumatoid arthritis 3 | 1,191
Skeletal muscle neoplasm 3 | 8
Waldenstrons macroglobulinemia 3 | 765
atypical teratoid/rhabdoid tumor 3 | 357
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
fibroadenoma 3 | 559
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Atopic dermatitis 2 | 952
cystic fibrosis 2 | 1,696

Tissue

Digestive Tract 42 | 17,369
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Endocrine System 40 | 18,159
Female tissues 39 | 17,400
Blood and immune system 37 | 16,909
Nervous System 37 | 16,725
Urinary Tract 37 | 16,678
Liver and Pancreas 36 | 16,750
Cardiovascular System 33 | 15,192
Respiratory system 33 | 16,393

Target Family

Non-IDG 23 | 12,091
Transcription Factor 14 | 1,400
Epigenetic 3 | 242
Enzyme 1 | 4,145
GPCR 1 | 408
Kinase 1 | 634

UniProt Keyword

Myogenesis 43 | 43
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein myomixer MYMX Tdark Non-IDG 0.00000 0
Multiple epidermal growth factor-like domains protein 10 MEGF10 Tbio Non-IDG -1.34196 23.9 42
DNA-binding protein inhibitor ID-3 ID3 Tbio Transcription Factor -2.36130 229.3 402
Protein myomaker MYMK Tdark Non-IDG -1.24386 16.6 6
Histone-lysine N-methyltransferase KMT5B KMT5B Tchem Epigenetic -1.20275 14.3 158
Myogenin MYOG Tbio Transcription Factor -2.97963 827.3 659
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.16910 1355.7 632
Forkhead box protein K1 FOXK1 Tbio Transcription Factor -2.42390 266.0 150
Proline-rich protein 14 PRR14 Tbio Non-IDG -0.76170 6.46 60
Myogenic factor 5 MYF5 Tbio Transcription Factor -2.51865 298.8 320