Development Level

Tbio 42 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
cardiovascular system phenotyp... 3 | 36
decreased total body fat amoun... 3 | 207
increased circulating HDL chol... 3 | 80
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
decreased heart rate variabili... 2 | 13
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
increased vertical activity 2 | 24
thrombocytopenia 2 | 56
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal heart shape 1 | 5
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 37 | 11,493
ovarian cancer 32 | 8,520
osteosarcoma 28 | 7,950
atypical teratoid / rhabdoid tumor 22 | 5,112
glioblastoma 22 | 5,792
lung cancer 21 | 4,740
medulloblastoma, large-cell 20 | 6,241
ependymoma 19 | 4,679
psoriasis 19 | 6,694
Breast cancer 17 | 3,578
malignant mesothelioma 17 | 3,232
Kidney cancer 16 | 2,613
astrocytic glioma 16 | 2,597
Pick disease 14 | 1,894
Astrocytoma, Pilocytic 12 | 3,081
adult high grade glioma 12 | 3,801
invasive ductal carcinoma 12 | 2,951
oligodendroglioma 12 | 2,850
group 3 medulloblastoma 11 | 4,104
lung carcinoma 11 | 2,843
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
Alzheimer's disease 10 | 658
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
spina bifida 10 | 1,074
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
Cancer 8 | 2,499
ductal carcinoma in situ 8 | 1,745
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Intellectual disability 7 | 1,016
diabetes mellitus 7 | 1,728
lung adenocarcinoma 7 | 2,716
pediatric high grade glioma 7 | 1,064
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Cataract 8 multiple types 6 | 33
Cognitive delay 6 | 608
Down syndrome 6 | 499
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
mucosa-associated lymphoid tissue lymphoma 6 | 484
Dull intelligence 5 | 645
Kidney disease 5 | 430
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Muscle hypotonia 5 | 571
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
Gaucher disease type 1 4 | 180
Proteinuria 4 | 144
Rheumatoid arthritis 4 | 1,191
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Absent reflex 3 | 92
Absent tendon reflex 3 | 92
Cardiovascular system disease 3 | 246
Dementia 3 | 175
Depressive disorder 3 | 409
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Gait abnormality 3 | 135
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Oculocerebrorenal syndrome 3 | 29
Parkinson's disease 3 | 392
Prenatal onset 3 | 139
Reflex, Deep Tendon, Absent 3 | 92
Seizures 3 | 596
Skin cancer 3 | 469
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
breast carcinoma 3 | 1,638
fibroadenoma 3 | 559
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
posterior fossa group B ependymoma 3 | 416
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562

Tissue

Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Blood and immune system 47 | 16,909
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

UniProt Keyword

Coated pit 48 | 48
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein amnionless AMN Tbio Non-IDG -1.36104 18.1 35
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
AP-1 complex subunit sigma-3 AP1S3 Tbio Non-IDG -0.58223 3.28 81
Epidermal growth factor receptor substrate 15 EPS15 Tbio Non-IDG -2.28374 174.5 164
AP-2 complex subunit alpha-1 AP2A1 Tbio Non-IDG -0.60535 3.75 186
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
Beta-arrestin-1 ARRB1 Tbio Non-IDG -2.63877 418.5 490
Dynamin-2 DNM2 Tchem Non-IDG -2.43547 282.5 143
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.72509 54.2 108