Development Level

Tbio 44 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased body weight 3 | 161
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
increased mean corpuscular vol... 3 | 92
abnormal behavior 2 | 298
decreased body length 2 | 101
decreased circulating insulin ... 2 | 76
embryonic lethality prior to t... 2 | 278
increased grip strength 2 | 41
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
decreased B cell number 1 | 5
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
enlarged epididymis 1 | 31
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
limb grasping 1 | 41

Disease

ovarian cancer 31 | 8,520
osteosarcoma 28 | 7,950
Carcinoma 26 | 11,493
medulloblastoma, large-cell 21 | 6,241
glioblastoma 19 | 5,792
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 13 | 4,679
Pick disease 12 | 1,894
lung cancer 11 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Astrocytoma, Pilocytic 8 | 3,081
Hypomyelinating leukodystrophy 6 8 | 26
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Congenital disorder of glycosylation 7 | 54
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
Breast cancer 6 | 3,578
Multiple myeloma 6 | 1,332
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Alzheimer's disease 5 | 658
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
pediatric high grade glioma 5 | 1,064
primitive neuroectodermal tumor 5 | 3,035
progressive supranuclear palsy 5 | 676
Autosomal recessive predisposition 4 | 1,442
Kidney cancer 4 | 2,613
Prostatic Neoplasms 4 | 495
juvenile dermatomyositis 4 | 1,187
oligodendroglioma 4 | 2,850
tuberculosis 4 | 2,010
tuberculosis and treatment for 6 months 4 | 409
Cataract 8 multiple types 3 | 33
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Heart disease 3 | 306
Intellectual disability 3 | 1,016
Mental and motor retardation 3 | 608
Multiple Sclerosis 3 | 540
Oculocerebrorenal syndrome 3 | 29
Rheumatoid arthritis 3 | 1,191
Tetanus 3 | 68
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
hereditary spastic paraplegia 3 | 318
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 3 months 3 | 179
Atopic dermatitis 2 | 952
Atrophy of cerebellum 2 | 103
Autosomal dominant Robinow syndrome 2 2 | 22
Bipolar Disorder 2 | 666
Cerebellar degeneration 2 | 103
Cerebral atrophy 2 | 178
Chylomicron retention disease 2 | 11
Coronary artery disease 2 | 268
Degenerative brain disorder 2 | 100
Down syndrome 2 | 499
Dull intelligence 2 | 645
Hypohidrosis 2 | 34
Hypoplasia of corpus callosum 2 | 90
Infratentorial atrophy 2 | 103
Irritation - emotion 2 | 68
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Monkeypox 2 | 12
Muscle hypotonia 2 | 571
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Progressive microcephaly 2 | 32
Secretory diarrhea 2 | 10
Short stature 2 | 531
Spastic Quadriplegia 2 | 42
Supratentorial atrophy 2 | 94
adrenocortical carcinoma 2 | 1,428
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 547
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 48 | 16,909
Cardiovascular System 48 | 15,192
Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678

Target Family

Non-IDG 37 | 12,091
Enzyme 11 | 4,145

Reactome Pathway

Retrograde transport at the Tr... 48 | 48
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-alpha-acetyltransferase 38, NatC auxiliary subunit NAA38 Tdark Enzyme -0.32247 2.02 32
Trans-Golgi network integral membrane protein 2 TGOLN2 Tbio Non-IDG -2.09006 106.0 218
Short coiled-coil protein SCOC Tbio Non-IDG -0.99386 9.57 48
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.60083 40.3 126
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127
Vacuolar protein sorting-associated protein 51 homolog VPS51 Tbio Non-IDG -2.64126 419.3 58
N-alpha-acetyltransferase 30 NAA30 Tbio Enzyme -1.33891 22.8 59
Rho-related BTB domain-containing protein 3 RHOBTB3 Tbio Non-IDG -0.85594 8.08 81
Ras-related protein Rab-43 RAB43 Tbio Enzyme -1.58430 37.0 70
Ras-related protein Rab-9A RAB9A Tbio Enzyme -0.89163 7.82 177