Development Level

Tbio 54 | 11,651
Tdark 8 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

decreased total body fat amoun... 2 | 207
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal nail morphology 1 | 8
cataract 1 | 92
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased red blood cell distr... 1 | 34

Disease

Carcinoma 53 | 11,493
ovarian cancer 33 | 8,520
osteosarcoma 26 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
lung adenocarcinoma 25 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
psoriasis 23 | 6,694
Breast cancer 21 | 3,578
pancreatic cancer 19 | 2,398
Astrocytoma, Pilocytic 16 | 3,081
cystic fibrosis 16 | 1,696
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
pituitary cancer 16 | 1,972
atypical teratoid / rhabdoid tumor 15 | 5,112
Kidney cancer 12 | 2,613
invasive ductal carcinoma 12 | 2,951
nasopharyngeal carcinoma 12 | 1,058
non-small cell lung cancer 12 | 2,890
active Crohn's disease 11 | 922
adult high grade glioma 11 | 3,801
malignant mesothelioma 11 | 3,232
group 4 medulloblastoma 10 | 1,855
Cancer 9 | 2,499
active ulcerative colitis 9 | 764
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
group 3 medulloblastoma 9 | 4,104
interstitial cystitis 9 | 2,312
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
ductal carcinoma in situ 8 | 1,745
lung carcinoma 8 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
spina bifida 8 | 1,074
Atopic dermatitis 7 | 952
esophageal adenocarcinoma 7 | 737
ulcerative colitis 7 | 1,819
Liver cancer 6 | 604
diabetes mellitus 6 | 1,728
Large intestine cancer 5 | 126
Multiple myeloma 5 | 1,332
colon cancer 5 | 1,478
non primary Sjogren syndrome sicca 5 | 891
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 167
Biliary papillomatosis 4 | 4
Endometrial cancer 4 | 311
Lymphoid leukemia 4 | 160
Melanoma 4 | 711
Otitis Media 4 | 52
Rheumatoid arthritis 4 | 1,191
cutaneous lupus erythematosus 4 | 1,057
facioscapulohumeral dystrophy 4 | 288
gastric carcinoma 4 | 807
interstitial lung disease 4 | 298
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Gastritis 3 | 47
IGA Glomerulonephritis 3 | 50
Immune system cancer 3 | 140
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Systemic scleroderma 3 | 60
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Arthritis, Rheumatoid 2 | 174
Bipolar Disorder 2 | 666
Cardiovascular system disease 2 | 246
Chronic obstructive pulmonary disease 2 | 184
Liver Cirrhosis, Experimental 2 | 769
Multiple Sclerosis 2 | 540
Pneumonia 2 | 174
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
atypical teratoid/rhabdoid tumor 2 | 357
dermatomyositis 2 | 966
periodontitis 2 | 293
posterior fossa group A ependymoma 2 | 468

Tissue

Digestive Tract 60 | 17,369
Skin and soft tissues 59 | 17,230
Female tissues 58 | 17,400
Endocrine System 57 | 18,159
Blood and immune system 56 | 16,909
Respiratory system 56 | 16,393
Liver and Pancreas 54 | 16,750
Urinary Tract 54 | 16,678
Male tissues 53 | 17,142
Nervous System 52 | 16,725
Cardiovascular System 40 | 15,192

Target Family

Enzyme 46 | 4,145
Non-IDG 18 | 12,091

Reactome Pathway

O-linked glycosylation of muci... 64 | 64
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-3B MUC3B Tdark Non-IDG -0.33279 3.75 0
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tbio Enzyme -0.54647 3.29 37
Polypeptide N-acetylgalactosaminyltransferase 12 GALNT12 Tbio Enzyme -0.82091 6.75 61
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 B3GNT7 Tdark Enzyme -0.65190 4.07 79
Polypeptide N-acetylgalactosaminyltransferase-like 6 GALNTL6 Tbio Enzyme -0.17205 1.56 24
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 B3GNT8 Tbio Enzyme 0.00000 1.00 8
Mucin-6 MUC6 Tbio Non-IDG -2.27683 174.7 140
Mucin-7 MUC7 Tbio Non-IDG -1.96964 94.4 94
C1GALT1-specific chaperone 1 C1GALT1C1 Tbio Enzyme -2.06337 115.1 36
Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 GALNTL5 Tbio Enzyme -0.40512 3.53 79