Development Level

Tbio 95 | 11,651
Tdark 25 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 5 | 298
embryonic lethality prior to o... 4 | 239
hyperactivity 3 | 148
increased fasted circulating g... 3 | 76
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased circulating creatini... 2 | 38
increased or absent threshold ... 2 | 101
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased IgE level 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

Carcinoma 82 | 11,493
ovarian cancer 71 | 8,520
osteosarcoma 63 | 7,950
medulloblastoma, large-cell 46 | 6,241
psoriasis 45 | 6,694
group 3 medulloblastoma 41 | 4,104
glioblastoma 39 | 5,792
atypical teratoid / rhabdoid tumor 35 | 5,112
lung cancer 35 | 4,740
ependymoma 34 | 4,679
malignant mesothelioma 28 | 3,232
primitive neuroectodermal tumor 28 | 3,035
Multiple myeloma 26 | 1,332
oligodendroglioma 26 | 2,850
Breast cancer 23 | 3,578
Kidney cancer 23 | 2,613
Pick disease 23 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
astrocytic glioma 22 | 2,597
acute quadriplegic myopathy 21 | 1,158
adult high grade glioma 20 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung adenocarcinoma 18 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
non-small cell lung cancer 17 | 2,890
diabetes mellitus 16 | 1,728
Waldenstrons macroglobulinemia 14 | 765
dermatomyositis 14 | 966
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
subependymal giant cell astrocytoma 14 | 2,287
astrocytoma 13 | 1,146
invasive ductal carcinoma 13 | 2,951
progressive supranuclear palsy 13 | 676
Cancer 10 | 2,499
pituitary cancer 10 | 1,972
Astrocytoma, Pilocytic 9 | 3,081
Gaucher disease type 1 9 | 180
Intellectual disability 9 | 1,016
group 4 medulloblastoma 9 | 1,855
Obesity 8 | 678
Rheumatoid arthritis 8 | 1,191
acute myeloid leukemia 8 | 783
breast carcinoma 8 | 1,638
hepatocellular carcinoma 8 | 547
juvenile dermatomyositis 8 | 1,187
spina bifida 8 | 1,074
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
aldosterone-producing adenoma 7 | 665
colon cancer 7 | 1,478
nasopharyngeal carcinoma 7 | 1,058
pancreatic cancer 7 | 2,398
Broad flat nasal bridge 6 | 236
Conductive hearing loss 6 | 123
Glaucoma 6 | 239
Male infertility 6 | 206
Nasal bridge wide 6 | 236
Nystagmus 6 | 317
Schizophrenia 6 | 1,160
interstitial lung disease 6 | 298
pediatric high grade glioma 6 | 1,064
sonic hedgehog group medulloblastoma 6 | 467
Abnormality of retinal pigmentation 5 | 111
Abnormality of the retinal vasculature 5 | 59
Amyotrophic lateral sclerosis 5 | 451
Anteverted nostril 5 | 191
Atypical scarring of skin 5 | 62
Blind Vision 5 | 111
Blindness, Legal 5 | 110
Cataract 5 | 297
Congenital anomaly of testis 5 | 52
Congenital hypoplasia of penis 5 | 176
Electroretinogram abnormal 5 | 95
HIV Infections 5 | 102
Hyperinsulinism 5 | 133
Hypogonadism 5 | 173
Keratoconus 5 | 113
Lens Opacities 5 | 231
Night blindness, progressive 5 | 51
Ophthalmoplegia 5 | 106
Optic Atrophy 5 | 242
Photodysphoria 5 | 121
Photophobia 5 | 121
Retinal pigment epithelial abnormality 5 | 111
Retinitis Pigmentosa 5 | 226
Sensorineural Hearing Loss (disorder) 5 | 284
adrenocortical carcinoma 5 | 1,428
ductal carcinoma in situ 5 | 1,745
lung carcinoma 5 | 2,843
non primary Sjogren syndrome sicca 5 | 891
Disease Progression 4 | 136
Polycystic ovary syndrome 4 | 360
Stomach Neoplasms 4 | 300
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
tuberculosis 4 | 2,010
tuberculosis and treatment for 3 months 4 | 179

Tissue

Endocrine System 121 | 18,159
Female tissues 116 | 17,400
Male tissues 116 | 17,142
Respiratory system 116 | 16,393
Blood and immune system 115 | 16,909
Digestive Tract 115 | 17,369
Liver and Pancreas 115 | 16,750
Nervous System 115 | 16,725
Skin and soft tissues 115 | 17,230
Urinary Tract 115 | 16,678
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 112 | 12,091
Enzyme 10 | 4,145

PANTHER Protein Class (2)

mRNA processing factor 122 | 122
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly(A)-specific ribonuclease PNLDC1 PNLDC1 Tbio Enzyme -0.61101 2.88 60
U6 snRNA-associated Sm-like protein LSm7 LSM7 Tbio Non-IDG -0.95219 6.58 100
U4/U6 small nuclear ribonucleoprotein Prp4 PRPF4 Tchem Non-IDG -0.61497 4.52 86
Poly(A) polymerase alpha PAPOLA Tbio Enzyme -0.76388 5.75 90
Pre-mRNA-processing factor 39 PRPF39 Tdark Non-IDG -0.30103 2.33 106
Splicing factor 3A subunit 3 SF3A3 Tbio Non-IDG -1.29518 20.1 78
Splicing factor, suppressor of white-apricot homolog SFSWAP Tdark Non-IDG -0.39794 2.82 147
RNA-binding motif protein, Y chromosome, family 1 member B RBMY1B Tbio Non-IDG 0.00000 2
Cleavage and polyadenylation specificity factor subunit 5 NUDT21 Tbio Non-IDG -1.56364 34.0 119
Cleavage stimulation factor subunit 2 tau variant CSTF2T Tbio Non-IDG -0.87334 8.94 128