Development Level

Tchem 75 | 1,598
Tclin 70 | 613
Tbio 39 | 11,445
Tdark 37 | 6,588

Collection

GPCR: IDG Consortium (Targets) 43 | 126
GPCR: IDG Consortium (Complete... 7 | 25
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

decreased vertical activity 9 | 208
abnormal behavior 8 | 298
hyperactivity 6 | 148
preweaning lethality, complete... 5 | 979
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
increased mean corpuscular vol... 4 | 92
abnormal heart morphology 3 | 162
abnormal kidney morphology 3 | 65
abnormal seminal vesicle morph... 3 | 114
abnormal skin coloration 3 | 25
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
absent vibrissae 2 | 12
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased eosinophil cell numb... 2 | 24
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased threshold for audito... 2 | 26
female infertility 2 | 60
impaired pupillary reflex 2 | 26
improved glucose tolerance 2 | 79
increased circulating triglyce... 2 | 42
increased mean platelet volume 2 | 45
male infertility 2 | 123
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal eye morphology 1 | 68
abnormal ileum morphology 1 | 2
abnormal liver morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal tail length 1 | 3
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased heart rate 1 | 23
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
mydriasis 1 | 6
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
scaly skin 1 | 4
short tibia 1 | 97
shortened RR interval 1 | 17
small adrenal glands 1 | 16
small kidney 1 | 16
small superior vagus ganglion 1 | 74
thick skin 1 | 4

Disease

Carcinoma 161 | 11,493
psoriasis 79 | 6,694
osteosarcoma 72 | 7,950
medulloblastoma, large-cell 60 | 6,241
Schizophrenia 57 | 1,160
glioblastoma 55 | 5,792
atypical teratoid / rhabdoid tumor 50 | 5,112
ovarian cancer 50 | 8,520
ependymoma 46 | 4,679
adult high grade glioma 45 | 3,801
Astrocytoma, Pilocytic 41 | 3,081
Bipolar Disorder 40 | 666
group 3 medulloblastoma 38 | 4,104
lung cancer 36 | 4,740
primitive neuroectodermal tumor 34 | 3,035
Depressive disorder 33 | 409
invasive ductal carcinoma 32 | 2,951
Major Depressive Disorder 31 | 301
Alcoholic Intoxication, Chronic 30 | 289
Mood Disorders 30 | 184
Obesity 30 | 678
oligodendroglioma 30 | 2,850
lung carcinoma 29 | 2,843
malignant mesothelioma 29 | 3,232
astrocytic glioma 28 | 2,597
interstitial cystitis 28 | 2,312
lung adenocarcinoma 28 | 2,716
non-small cell lung cancer 28 | 2,890
Mental Depression 26 | 333
diabetes mellitus 26 | 1,728
Asthma 25 | 385
Cancer 25 | 2,499
Parkinson's disease 24 | 392
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
pituitary cancer 23 | 1,972
Allergic rhinitis 22 | 94
Epilepsy 22 | 792
Unipolar Depression 22 | 250
Kidney cancer 21 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
tuberculosis 21 | 2,010
Breast cancer 20 | 3,578
pancreatic cancer 19 | 2,398
Migraine 18 | 83
Nasal discharge 18 | 24
ductal carcinoma in situ 18 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Alcohol dependence 17 | 107
Attention deficit hyperactivity disorder 17 | 278
Nasal congestion 17 | 21
breast carcinoma 17 | 1,638
Common cold 16 | 67
Pain 16 | 103
Pain agnosia 16 | 104
Autistic Disorder 15 | 364
Hypertension 15 | 396
colon cancer 15 | 1,478
ulcerative colitis 15 | 1,819
Seizures 14 | 596
adrenocortical carcinoma 14 | 1,428
group 4 medulloblastoma 14 | 1,855
subependymal giant cell astrocytoma 14 | 2,287
Asthma management 13 | 19
Bronchitis 13 | 43
Pulmonary emphysema 13 | 48
Substance Withdrawal Syndrome 13 | 55
Acute exacerbation of asthma 12 | 14
Cocaine-Related Disorders 12 | 92
Hypertensive disorder 12 | 56
Multiple Sclerosis 12 | 540
Opiate dependence 12 | 29
Alzheimer's disease 11 | 658
Cocaine Dependence 11 | 51
General anesthesia 11 | 53
Hyperalgesia 11 | 83
Hypotension 11 | 82
Influenza-like symptoms 11 | 16
Substance abuse 11 | 59
cutaneous lupus erythematosus 11 | 1,057
cystic fibrosis 11 | 1,696
Acromegaly 10 | 51
Alcohol abuse 10 | 50
Atopic dermatitis 10 | 952
Cerebrovascular disease 10 | 238
Headache disorder 10 | 19
Melanoma 10 | 711
Open-angle glaucoma 10 | 27
Sinus headache 10 | 16
mucosa-associated lymphoid tissue lymphoma 10 | 484
obsessive-compulsive disorder 10 | 61
primary Sjogren syndrome 10 | 735
Amphetamine-Related Disorders 9 | 74
Liver Cirrhosis, Experimental 9 | 769
Pick disease 9 | 1,894
Psychotic Disorders 9 | 151
Status Epilepticus 9 | 98
Vascular disease 9 | 319
astrocytoma 9 | 1,146
medulloblastoma 9 | 720
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962

Tissue

Endocrine System 191 | 18,159
Nervous System 179 | 16,725
Digestive Tract 170 | 17,369
Female tissues 167 | 17,400
Skin and soft tissues 165 | 17,230
Male tissues 158 | 17,142
Blood and immune system 156 | 16,909
Urinary Tract 152 | 16,678
Liver and Pancreas 149 | 16,750
Respiratory system 142 | 16,393
Cardiovascular System 127 | 15,192

Target Family

GPCR 191 | 408
oGPCR 17 | 421
Non-IDG 7 | 12,091
Transporter 3 | 473
Ion Channel 2 | 344
Enzyme 1 | 4,145

PANTHER Protein Class (1)

G-protein coupled receptor 221 | 221
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Medium-wave-sensitive opsin 2 OPN1MW2 Tdark GPCR 0.00000 0
Medium-wave-sensitive opsin 3 OPN1MW3 Tdark GPCR 0.00000 0
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
Probable G-protein coupled receptor 132 GPR132 Tchem GPCR -2.72228 494.8 185