Development Level

Tbio 309 | 11,445
Tchem 109 | 1,598
Tdark 93 | 6,588
Tclin 69 | 613

Collection

Ion Channel: IDG Consortium (T... 40 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 32 | 979
preweaning lethality, incomple... 16 | 499
embryonic lethality prior to t... 13 | 278
embryonic lethality prior to o... 12 | 239
abnormal embryo size 10 | 220
abnormal behavior 8 | 298
decreased prepulse inhibition 8 | 82
decreased vertical activity 7 | 208
enlarged heart 7 | 210
embryonic growth retardation 6 | 106
impaired glucose tolerance 6 | 75
increased circulating HDL chol... 6 | 80
increased circulating alkaline... 6 | 122
increased lean body mass 6 | 172
increased mean corpuscular hem... 6 | 96
abnormal bone structure 5 | 187
abnormal eye morphology 5 | 68
abnormal heart morphology 5 | 162
abnormal seminal vesicle morph... 5 | 114
decreased circulating glucose ... 5 | 126
decreased total body fat amoun... 5 | 207
hyperactivity 5 | 148
increased mean corpuscular vol... 5 | 92
increased startle reflex 5 | 112
limb grasping 5 | 41
abnormal gait 4 | 69
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 93
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
improved glucose tolerance 4 | 79
increased circulating choleste... 4 | 66
increased total body fat amoun... 4 | 134
short tibia 4 | 97
abnormal epididymis morphology 3 | 42
abnormal neural tube closure 3 | 46
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased body weight 3 | 161
decreased caudal vertebrae num... 3 | 53
decreased circulating alkaline... 3 | 46
decreased circulating amylase ... 3 | 28
decreased circulating calcium ... 3 | 36
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased mean corpuscular hem... 3 | 50
decreased red blood cell distr... 3 | 41
increased circulating serum al... 3 | 22
increased circulating total pr... 3 | 28
increased mean platelet volume 3 | 45
increased monocyte cell number 3 | 63
small superior vagus ganglion 3 | 74
abnormal behavioral response t... 2 | 66
abnormal coat appearance 2 | 31
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal hindbrain morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal midbrain development 2 | 20
abnormal pancreas morphology 2 | 13
abnormal response to new envir... 2 | 10
abnormal response to tactile s... 2 | 17
abnormal retina morphology 2 | 71
cardiovascular system phenotyp... 2 | 36
corneal opacity 2 | 32
corneal vascularization 2 | 6
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating glycerol... 2 | 16
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased eosinophil cell numb... 2 | 24
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased mean platelet volume 2 | 25
edema 2 | 59
enlarged epididymis 2 | 31
hydrometra 2 | 53
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating iron lev... 2 | 30
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small heart 2 | 10

Disease

Carcinoma 439 | 11,493
ovarian cancer 245 | 8,520
osteosarcoma 239 | 7,950
medulloblastoma, large-cell 221 | 6,241
psoriasis 209 | 6,694
glioblastoma 205 | 5,792
atypical teratoid / rhabdoid tumor 184 | 5,112
ependymoma 166 | 4,679
lung cancer 165 | 4,740
adult high grade glioma 136 | 3,801
group 3 medulloblastoma 130 | 4,104
Kidney cancer 127 | 2,613
lung carcinoma 126 | 2,843
Astrocytoma, Pilocytic 117 | 3,081
oligodendroglioma 114 | 2,850
primitive neuroectodermal tumor 113 | 3,035
Breast cancer 106 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 100 | 2,955
malignant mesothelioma 99 | 3,232
astrocytic glioma 98 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 94 | 3,291
non-small cell lung cancer 94 | 2,890
lung adenocarcinoma 93 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,989
subependymal giant cell astrocytoma 86 | 2,287
Pick disease 85 | 1,894
pancreatic cancer 84 | 2,398
Epilepsy 81 | 792
invasive ductal carcinoma 81 | 2,951
Autosomal recessive predisposition 78 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 76 | 1,962
interstitial cystitis 72 | 2,312
pituitary cancer 72 | 1,972
cystic fibrosis 68 | 1,696
Schizophrenia 59 | 1,160
colon cancer 59 | 1,478
tuberculosis 55 | 2,010
active Crohn's disease 51 | 922
ductal carcinoma in situ 51 | 1,745
Bipolar Disorder 49 | 666
ulcerative colitis 49 | 1,819
pediatric high grade glioma 47 | 1,064
Cancer 46 | 2,499
group 4 medulloblastoma 46 | 1,855
active ulcerative colitis 43 | 764
diabetes mellitus 43 | 1,728
Intellectual disability 40 | 1,016
adrenocortical carcinoma 40 | 1,428
Seizures 39 | 596
Melanoma 38 | 711
Multiple myeloma 38 | 1,332
Rheumatoid arthritis 37 | 1,191
breast carcinoma 37 | 1,638
Alzheimer's disease 36 | 658
astrocytoma 36 | 1,146
nasopharyngeal carcinoma 35 | 1,058
Autistic Disorder 32 | 364
Liver cancer 32 | 604
Alcoholic Intoxication, Chronic 31 | 289
Muscle hypotonia 31 | 571
non primary Sjogren syndrome sicca 31 | 891
progressive supranuclear palsy 31 | 676
Skin cancer 30 | 469
cutaneous lupus erythematosus 30 | 1,057
Failure to gain weight 29 | 365
Pediatric failure to thrive 29 | 365
primary pancreatic ductal adenocarcinoma 29 | 1,109
spina bifida 28 | 1,074
Colorectal Neoplasms 27 | 243
Dull intelligence 27 | 645
Liver Cirrhosis, Experimental 27 | 769
Low intelligence 27 | 645
Mental Retardation 27 | 645
Mental deficiency 27 | 645
Poor school performance 27 | 645
Hypertension 26 | 396
Parkinson's disease 26 | 392
Tonic-clonic epilepsy 26 | 47
Cognitive delay 25 | 608
Global developmental delay 25 | 608
Mental and motor retardation 25 | 608
acute quadriplegic myopathy 25 | 1,158
dermatomyositis 25 | 966
aldosterone-producing adenoma 24 | 665
juvenile dermatomyositis 24 | 1,187
Depressive disorder 23 | 409
General anesthesia 23 | 53
Infantile onset 23 | 238
Mental Depression 23 | 333
Atopic dermatitis 22 | 952
Cerebellar Ataxia 22 | 304
Cholestasis 22 | 155
Nicotine dependence 22 | 54
gastric carcinoma 22 | 807
Constipation 21 | 181
Diarrhea 21 | 253
Kidney disease 21 | 430
medulloblastoma 21 | 720
Waldenstrons macroglobulinemia 20 | 765
esophageal adenocarcinoma 20 | 737

Tissue

Endocrine System 558 | 18,159
Digestive Tract 533 | 17,369
Nervous System 529 | 16,725
Female tissues 525 | 17,400
Male tissues 523 | 17,142
Skin and soft tissues 522 | 17,230
Urinary Tract 515 | 16,678
Liver and Pancreas 509 | 16,750
Blood and immune system 506 | 16,909
Respiratory system 478 | 16,393
Cardiovascular System 432 | 15,192

Target Family

Transporter 267 | 473
Ion Channel 146 | 344
Non-IDG 112 | 12,091
Enzyme 45 | 4,145
GPCR 7 | 408
Kinase 3 | 634

PANTHER Protein Class (0)

transporter 580 | 580
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukocyte receptor cluster member 8 LENG8 Tdark Non-IDG 0.43 0.00000 29
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Solute carrier family 13 member 3 SLC13A3 Tbio Transporter -1.47363 31.7 92
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Proton-coupled amino acid transporter 2 SLC36A2 Tchem Transporter -1.78507 61.5 88
Transportin-3 TNPO3 Tbio Non-IDG -1.74707 55.2 105
Sodium/bile acid cotransporter SLC10A1 Tchem Transporter -2.69150 476.1 163
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Transient receptor potential cation channel subfamily M member 7 TRPM7 Tchem Ion Channel -2.53154 365.5 317