Development Level

Tbio 32 | 11,445
Tchem 7 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 3 | 239
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
increased blood urea nitrogen ... 1 | 48
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112

Disease

Carcinoma 30 | 11,493
psoriasis 22 | 6,694
ovarian cancer 17 | 8,520
Anemia 16 | 365
osteosarcoma 14 | 7,950
lung cancer 12 | 4,740
Autosomal recessive predisposition 11 | 1,442
Cancer 11 | 2,499
medulloblastoma, large-cell 10 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Bilirubin metabolic disorder 9 | 41
Sickle Cell Anemia 9 | 53
malignant mesothelioma 9 | 3,232
Porphyria 8 | 10
Epilepsy 7 | 792
Hereditary coproporphyria 7 | 8
Pericholangitis 7 | 8
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
tuberculosis 7 | 2,010
Acute intermittent porphyria 6 | 15
Erythropoietic protoporphyria 6 | 15
Photosensitivity of skin 6 | 51
Variegate Porphyria 6 | 10
Anemia, Hemolytic 5 | 55
Breast cancer 5 | 3,578
Cholelithiasis 5 | 33
Diarrhea 5 | 253
Neonatal Jaundice 5 | 30
Porphyria cutanea tarda 5 | 12
Seizures 5 | 596
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
Abdominal Pain 4 | 98
Attention deficit hyperactivity disorder 4 | 278
Cerebellar Ataxia 4 | 304
Constipation 4 | 181
Cutaneous porphyria 4 | 6
Depressive disorder 4 | 409
Dysarthria 4 | 192
Dyschezia 4 | 135
Hepatomegaly 4 | 285
Hypertensive disease 4 | 292
Hypertrichosis 4 | 46
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Prostatic Neoplasms 4 | 495
Vomiting 4 | 116
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Acute kidney injury 3 | 70
Chemical and Drug Induced Liver Injury 3 | 195
Cholestasis 3 | 155
Contact Dermatitis 3 | 81
Dermatitis, Contact 3 | 71
Dull intelligence 3 | 645
Electrocardiogram abnormal 3 | 81
Failure to gain weight 3 | 365
Hemoglobin low 3 | 124
Hypertension 3 | 396
Hypertrophic Cardiomyopathy 3 | 117
Liver Cirrhosis 3 | 181
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Melanoma 3 | 711
Mental deficiency 3 | 645
Muscle Weakness 3 | 170
Neuropathy 3 | 261
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Poor school performance 3 | 645
Proteinuria 3 | 144
Retinitis Pigmentosa 3 | 226
Schizophrenia 3 | 1,160
Short stature 3 | 531
Splenomegaly 3 | 190
Tachycardia 3 | 43
Thin skin 3 | 47
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
mucosa-associated lymphoid tissue lymphoma 3 | 484
pituitary cancer 3 | 1,972

Tissue

Liver and Pancreas 41 | 16,750
Digestive Tract 40 | 17,369
Urinary Tract 39 | 16,678
Skin and soft tissues 38 | 17,230
Male tissues 36 | 17,142
Female tissues 35 | 17,400
Endocrine System 34 | 18,159
Blood and immune system 32 | 16,909
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Cardiovascular System 24 | 15,192

Target Family

Enzyme 38 | 4,145
Non-IDG 3 | 12,091

KEGG Pathway

Porphyrin and chlorophyll meta... 41 | 41
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B11 UGT2B11 Tbio Enzyme -0.26858 1.79 52
Delta-aminolevulinic acid dehydratase ALAD Tbio Enzyme -3.02024 1068.6 166
UDP-glucuronosyltransferase 1-6 UGT1A6 Tbio Enzyme -2.76648 608.6 64
Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial MMAB Tbio Enzyme -1.79208 63.7 92
UDP-glucuronosyltransferase 2B4 UGT2B4 Tbio Enzyme -1.58066 34.6 140
UDP-glucuronosyltransferase 1-7 UGT1A7 Tbio Enzyme -1.87803 74.6 24
UDP-glucuronosyltransferase 1-8 UGT1A8 Tbio Enzyme -1.68933 43.9 5
Bifunctional glutamate/proline--tRNA ligase EPRS Tchem Enzyme -3.11686 1267.4 98
Cytochrome c-type heme lyase HCCS Tbio Enzyme -3.36456 2284.3 220
Ceruloplasmin CP Tbio Non-IDG -2.88089 683.9 251