Development Level

Tbio 42 | 11,445
Tchem 20 | 1,598
Tclin 9 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to o... 3 | 239
abnormal retina morphology 2 | 71
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal forelimb morphology 1 | 2
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
cataract 1 | 92
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased B cell number 1 | 9
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36
small spleen 1 | 19
small testis 1 | 58
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

Carcinoma 66 | 11,493
ovarian cancer 53 | 8,520
osteosarcoma 45 | 7,950
Cancer 41 | 2,499
glioblastoma 40 | 5,792
atypical teratoid / rhabdoid tumor 39 | 5,112
lung cancer 34 | 4,740
Kidney cancer 31 | 2,613
ependymoma 31 | 4,679
medulloblastoma, large-cell 30 | 6,241
Breast cancer 28 | 3,578
psoriasis 28 | 6,694
Astrocytoma, Pilocytic 26 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
invasive ductal carcinoma 26 | 2,951
non-small cell lung cancer 25 | 2,890
malignant mesothelioma 23 | 3,232
primitive neuroectodermal tumor 23 | 3,035
adult high grade glioma 22 | 3,801
pancreatic cancer 22 | 2,398
group 4 medulloblastoma 21 | 1,855
oligodendroglioma 21 | 2,850
astrocytic glioma 19 | 2,597
interstitial cystitis 18 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Schizophrenia 17 | 1,160
ductal carcinoma in situ 17 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
breast carcinoma 16 | 1,638
lung adenocarcinoma 16 | 2,716
Stomach Neoplasms 15 | 300
diabetes mellitus 15 | 1,728
group 3 medulloblastoma 15 | 4,104
lung carcinoma 15 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
subependymal giant cell astrocytoma 14 | 2,287
Intellectual disability 13 | 1,016
Rheumatoid arthritis 13 | 1,191
Kidney disease 12 | 430
Neoplasm Invasiveness 12 | 161
Neoplasm Metastasis 12 | 168
Pick disease 12 | 1,894
Squamous cell carcinoma 12 | 129
adrenocortical carcinoma 12 | 1,428
primary pancreatic ductal adenocarcinoma 12 | 1,109
Bipolar Disorder 11 | 666
Breast Neoplasms 11 | 445
Carcinoma, Squamous Cell 11 | 110
acute quadriplegic myopathy 11 | 1,158
astrocytoma 11 | 1,146
dermatomyositis 11 | 966
juvenile dermatomyositis 11 | 1,187
pediatric high grade glioma 11 | 1,064
pituitary cancer 11 | 1,972
Craniofacial Abnormalities 10 | 151
Mammary Neoplasms 10 | 425
Multiple myeloma 10 | 1,332
Obesity 10 | 678
esophageal adenocarcinoma 10 | 737
spina bifida 10 | 1,074
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Colorectal Neoplasms 9 | 243
Dull intelligence 9 | 645
Liver Cirrhosis, Experimental 9 | 769
Low intelligence 9 | 645
Lung Neoplasms 9 | 232
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Prostatic Neoplasms 9 | 495
Short stature 9 | 531
Small head 9 | 374
Waldenstrons macroglobulinemia 9 | 765
Alzheimer's disease 8 | 658
Autosomal recessive predisposition 8 | 1,442
Byzanthine arch palate 8 | 194
Melanoma 8 | 711
Orbital separation excessive 8 | 244
cystic fibrosis 8 | 1,696
Acquired scoliosis 7 | 281
Animal Mammary Neoplasms 7 | 136
Autistic Disorder 7 | 364
Carcinoma, Hepatocellular 7 | 228
Colonic Neoplasms 7 | 142
Curvature of spine 7 | 282
Endometrial cancer 7 | 311
Hypoplastic mandible condyle 7 | 275
Liver carcinoma 7 | 240
Lymphoid leukemia 7 | 160
Mammary Neoplasms, Animal 7 | 136
Mammary Neoplasms, Experimental 7 | 154
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Vascular disease 7 | 319
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
medulloblastoma 7 | 720
ovarian neoplasm 7 | 99
pancreatic carcinoma 7 | 562

Tissue

Digestive Tract 71 | 17,369
Endocrine System 71 | 18,159
Female tissues 71 | 17,400
Male tissues 71 | 17,142
Nervous System 71 | 16,725
Respiratory system 71 | 16,393
Skin and soft tissues 71 | 17,230
Urinary Tract 71 | 16,678
Blood and immune system 70 | 16,909
Liver and Pancreas 70 | 16,750
Cardiovascular System 68 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 20 | 634
Enzyme 13 | 4,145
Transcription Factor 9 | 1,400
Epigenetic 2 | 242

KEGG Pathway

Adherens junction 72 | 72
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability