Development Level

Tbio 40 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hydrops fetalis 1 | 1
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating insulin ... 1 | 3
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74

Disease

Carcinoma 38 | 11,493
osteosarcoma 27 | 7,950
ovarian cancer 26 | 8,520
psoriasis 23 | 6,694
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 16 | 4,104
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
lung cancer 14 | 4,740
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
lung adenocarcinoma 12 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
ductal carcinoma in situ 8 | 1,745
Cancer 7 | 2,499
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
group 4 medulloblastoma 6 | 1,855
primary pancreatic ductal adenocarcinoma 6 | 1,109
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Multiple myeloma 5 | 1,332
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
esophageal adenocarcinoma 5 | 737
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
fibroadenoma 4 | 559
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 952
Intellectual disability 3 | 1,016
Neurodegenerative disease 3 | 414
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Asthma 2 | 385
Atherosclerosis 2 | 291
Breast Neoplasms 2 | 445
Cleft Palate 2 | 271
Colorectal adenoma 2 | 15
Composite lymphoma 2 | 3
Congenital diaphragmatic hernia 2 | 67
Congenital hypoplasia of penis 2 | 176
Craniofacial Abnormalities 2 | 151
Cryptorchidism 2 | 296
Dental caries 2 | 164
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Exudative vitreoretinopathy 2 | 15
Hypersensitivity reaction type II disease 2 | 253
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Mammary Neoplasms 2 | 425
Multiple Sclerosis 2 | 540
Neuropathy 2 | 261
Norrie disease 2 | 14
Polycystic ovary syndrome 2 | 360
Polydactyly 2 | 107
Prostatic Neoplasms 2 | 495
Retinopathy of prematurity 2 | 22
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
fascioscapulohumeral muscular dystrophy 2 | 100
glioblastoma multiforme 2 | 142
hearing impairment 2 | 199
interstitial lung disease 2 | 298
mucosa-associated lymphoid tissue lymphoma 2 | 484
posterior fossa group A ependymoma 2 | 468
progressive supranuclear palsy 2 | 676
Iron metabolism disease 1 | 20
Poor speech 1 | 37

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Skin and soft tissues 47 | 17,230
Nervous System 46 | 16,725
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192
Respiratory system 44 | 16,393

Target Family

Non-IDG 26 | 12,091
Enzyme 10 | 4,145
GPCR 7 | 408
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

Jensen-KB Tissue

Gastroesophageal cancer cell 48 | 48
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 766 ZNF766 Tdark Transcription Factor 0.00000 46
Frizzled-5 FZD5 Tbio GPCR -1.54924 30.5 307
Guanylate-binding protein 6 GBP6 Tbio Non-IDG -0.76488 5.40 61
Frizzled-1 FZD1 Tbio GPCR -2.07049 78.4 286
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202
Apoptosis-inducing factor 2 AIFM2 Tbio Non-IDG -1.22943 14.9 217
StAR-related lipid transfer protein 3 STARD3 Tbio Non-IDG -1.61721 39.4 37
BRCA1-A complex subunit RAP80 UIMC1 Tbio Non-IDG -1.69622 52.7 176
Kinase D-interacting substrate of 220 kDa KIDINS220 Tbio Enzyme -2.42897 262.3 191
Frizzled-4 FZD4 Tbio GPCR -2.05508 106.8 313