Development Level

Tbio 24 | 11,445
Tdark 3 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal skin appearance 1 | 3
abnormal thoracic cage shape 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating aspartat... 1 | 34
decreased circulating lactate ... 1 | 3
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
pallor 1 | 34

Disease

Carcinoma 17 | 11,493
glioblastoma 16 | 5,792
osteosarcoma 16 | 7,950
medulloblastoma, large-cell 15 | 6,241
ovarian cancer 15 | 8,520
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
psoriasis 12 | 6,694
lung cancer 11 | 4,740
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 10 | 3,801
invasive ductal carcinoma 10 | 2,951
oligodendroglioma 9 | 2,850
astrocytic glioma 8 | 2,597
primitive neuroectodermal tumor 8 | 3,035
group 3 medulloblastoma 7 | 4,104
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
ductal carcinoma in situ 6 | 1,745
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
tuberculosis 6 | 2,010
lung carcinoma 5 | 2,843
Autosomal recessive predisposition 4 | 1,442
Griscelli syndrome 4 | 24
Hypomyelinating leukodystrophy 6 4 | 26
Kidney cancer 4 | 2,613
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
ARC syndrome 3 | 13
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Pediatric failure to thrive 3 | 365
Rheumatoid arthritis 3 | 1,191
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
ulcerative colitis 3 | 1,819
Arthritis, Rheumatoid 2 | 174
Autosomal dominant Robinow syndrome 2 2 | 22
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Diaphragmatic Hernia 2 | 40
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Epileptic encephalopathy 2 | 26
Febrile Convulsions 2 | 14
Hernia, Diaphragmatic 2 | 40
Hypsarrhythmia 2 | 25
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
Multiple Sclerosis 2 | 540
Schizophrenia 2 | 1,160
Tetanus 2 | 68
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
Bronchiectasis 1 | 64
Centronuclear myopathy 1 | 27
Choledochal Cyst 1 | 9
Cortical blindness 1 | 16
Early myoclonic encephalopathy 1 | 15
Hemolytic-Uremic Syndrome 1 | 30
Hypercalciuria 1 | 27
Increased calcium level in kidney 1 | 21
Kindler syndrome 1 | 11
Neonatal onset 1 | 21
Non-obstructive azoospermia 1 | 21
Polycystic Kidney, Autosomal Recessive 1 | 9
Sinusitis 1 | 65
Tonic - clonic seizures 1 | 44

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Female tissues 28 | 17,400
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 6 | 4,145
Ion Channel 2 | 344

GO Process

vesicle docking involved in ex... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vacuolar protein sorting-associated protein 45 VPS45 Tbio Non-IDG -1.57344 40.0 212
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Vacuolar protein sorting-associated protein 11 homolog VPS11 Tbio Non-IDG 0.00000 170
Ras-related protein Rab-8B RAB8B Tbio Enzyme -0.91719 6.86 179
Exocyst complex component 6 EXOC6 Tbio Non-IDG -1.56101 35.8 46
Pleckstrin PLEK Tbio Non-IDG -3.00624 743.7 290
Rab9 effector protein with kelch motifs RABEPK Tdark Non-IDG 0.34 0.41 155
Syntaxin-binding protein 3 STXBP3 Tbio Non-IDG -1.41720 31.3 146
Vesicle transport through interaction with t-SNAREs homolog 1B VTI1B Tbio Non-IDG -1.86140 62.7 174