Development Level

Tbio 23 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
small testis 1 | 58

Disease

ovarian cancer 20 | 8,520
Carcinoma 18 | 11,493
Cancer 17 | 2,499
Breast cancer 16 | 3,578
medulloblastoma, large-cell 16 | 6,241
glioblastoma 15 | 5,792
osteosarcoma 15 | 7,950
lung cancer 14 | 4,740
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung carcinoma 11 | 2,843
psoriasis 11 | 6,694
lung adenocarcinoma 10 | 2,716
malignant mesothelioma 10 | 3,232
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
non-small cell lung cancer 9 | 2,890
Brachydactyly 8 | 156
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
acute quadriplegic myopathy 8 | 1,158
ductal carcinoma in situ 8 | 1,745
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Acquired scoliosis 6 | 281
Congenital heart disease 6 | 93
Cryptorchidism 6 | 296
Curvature of spine 6 | 282
Exophthalmos 6 | 112
Glaucoma 6 | 239
Hypertensive disease 6 | 292
Kidney cancer 6 | 2,613
Prominent eyes 6 | 96
Prominent globes 6 | 96
Protruding eyes 6 | 96
Strabismus 6 | 270
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
subependymal giant cell astrocytoma 6 | 2,287
Bilateral fifth finger clinodactyly 5 | 110
Cleft Palate 5 | 271
Craniofacial Abnormalities 5 | 151
Curvature of little finger 5 | 110
Increase in blood pressure 5 | 119
Preauricular Fistulae, Congenital 5 | 27
Preauricular dimple 5 | 27
Preauricular sinus 5 | 27
Short philtrum 5 | 53
Short stature 5 | 531
Tetralogy of Fallot 5 | 63
Type 2 diabetes mellitus 5 | 272
Underdeveloped brows 5 | 38
Underdeveloped supraorbital ridges 5 | 38
pediatric high grade glioma 5 | 1,064
tuberculosis 5 | 2,010
Abnormal nasal morphology 4 | 16
Broad forehead 4 | 59
Carcinoma, Pancreatic Ductal 4 | 20
Cardiomegaly 4 | 116
Congenital deafness 4 | 185
Cutis marmorata 4 | 32
Deafness 4 | 198
Epilepsy 4 | 792
Hearing Loss, Partial 4 | 185
Heart disease 4 | 306
Long narrow head 4 | 75
Narrow cranium shape 4 | 75
Narrow head shape 4 | 75
Narrow skull shape 4 | 75
Orbital separation excessive 4 | 244
Patent ductus arteriosus 4 | 90
Seizures 4 | 596
Small head 4 | 374
Thin lips 4 | 49
Turridolichocephaly 4 | 75
Ventricular Septal Defects 4 | 119
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
hearing impairment 4 | 199
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Failure to gain weight 3 | 365

Tissue

Cardiovascular System 29 | 15,192
Female tissues 29 | 17,400
Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393

Target Family

Transcription Factor 14 | 1,400
Non-IDG 11 | 12,091
Kinase 4 | 634

GO Process

ventricular septum morphogenes... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Noggin NOG Tbio Non-IDG -2.95258 841.0 338
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413
Protein Wnt-11 WNT11 Tbio Non-IDG -2.08846 121.9 99
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Egl nine homolog 1 EGLN1 Tchem Non-IDG -2.48717 306.7 391
Fibroblast growth factor receptor-like 1 FGFRL1 Tbio Non-IDG -1.53083 37.2 212
Hairy/enhancer-of-split related with YRPW motif protein 2 HEY2 Tbio Transcription Factor -2.43307 261.2 173
Activin receptor type-1 ACVR1 Tchem Kinase -2.47071 290.9 428
Hairy/enhancer-of-split related with YRPW motif-like protein HEYL Tbio Transcription Factor -2.01284 99.3 277