Development Level

Tbio 18 | 10,625
Tchem 5 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

embryonic lethality prior to t... 3 | 187
preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
abnormal QRS complex 1 | 25
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal embryo development 1 | 2
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal iris morphology 1 | 12
abnormal motor learning 1 | 4
abnormal pelvic girdle bone mo... 1 | 11
abnormal pericardium morpholog... 1 | 11
abnormal retinal vasculature m... 1 | 15
cataract 1 | 26
cleft palate 1 | 6
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased lean body mass 1 | 195
enlarged heart 1 | 111
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased heart rate variabili... 1 | 4
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
limb grasping 1 | 35
preweaning lethality, incomple... 1 | 260

Disease

osteosarcoma 12 | 7,933
ovarian cancer 11 | 8,492
psoriasis 11 | 6,685
interstitial cystitis 9 | 2,299
Polydactyly 8 | 93
atypical teratoid / rhabdoid tumor 8 | 4,369
invasive ductal carcinoma 8 | 2,950
Breast cancer 7 | 3,099
Carcinoma 7 | 2,147
chronic rhinosinusitis 7 | 512
glioblastoma 7 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Cancer 6 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
lung cancer 6 | 4,473
malignant mesothelioma 6 | 3,163
medulloblastoma, large-cell 6 | 6,234
sonic hedgehog group medulloblastoma 6 | 1,482
ependymoma 5 | 2,514
lung adenocarcinoma 5 | 2,714
pituitary cancer 5 | 1,972
posterior fossa group B ependymoma 5 | 1,530
Asphyxiating thoracic dystrophy 4 | 34
Ciliopathy 4 | 57
Cleft palate 4 | 125
Sensenbrenner syndrome 4 | 15
Synostosis 4 | 18
atypical teratoid/rhabdoid tumor 4 | 1,095
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
pilocytic astrocytoma 4 | 3,086
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
ulcerative colitis 4 | 2,087
Ellis-Van Creveld syndrome 3 | 19
Jeune thoracic dystrophy 3 | 9
Nevoid basal cell carcinoma syndrome 3 | 9
Pick disease 3 | 1,893
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,670
ductal carcinoma in situ 3 | 1,745
lung carcinoma 3 | 2,844
subependymal giant cell astrocytoma 3 | 2,287
Achondroplasia 2 | 20
Acute Promyelocytic Leukemia 2 | 32
Adenoma 2 | 165
Agnathia-otocephaly complex 2 | 8
Ameloblastoma 2 | 25
Bardet-Biedl Syndrome 2 | 40
Basal cell carcinoma of skin 2 | 2
Bladder Neoplasm 2 | 109
Brachydactyly 2 | 52
Cleft Lip 2 | 91
Complex regional pain syndrome 2 | 12
Down syndrome 2 | 548
Holoprosencephaly 2 | 52
Joubert syndrome 2 | 62
Mammary Neoplasms 2 | 410
Multiple myeloma 2 | 1,328
Pallister-Hall syndrome 2 | 11
Prostatic Neoplasms 2 | 471
Short rib-polydactyly syndrome, Verma-Naumoff type 2 | 5
Short-rib thoracic dysplasia 3 with or without polydactyly 2 | 9
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
colon cancer 2 | 1,475
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 967
fibroadenoma 2 | 557
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
non-small cell lung carcinoma 2 | 413
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
progressive supranuclear palsy 2 | 674
tuberculosis 2 | 1,563
Adult T-cell leukemia 1 | 5
Ankylosis 1 | 25
Bone Diseases, Developmental 1 | 25
Brain Neoplasms 1 | 23
Congenital ocular coloboma (disorder) 1 | 12
Dysostosis 1 | 3
Hereditary diffuse gastric cancer 1 | 4
Jaw Abnormalities 1 | 5
Joubert syndrome with orofaciodigital defect 1 | 8
Klinefelter's syndrome 1 | 59
Neuroectodermal Tumor, Primitive 1 | 8
Ollier disease 1 | 15
Respiratory Insufficiency 1 | 11
Temtamy preaxial brachydactyly syndrome 1 | 2

Tissue

Endocrine System 24 | 18,512
Liver and Pancreas 24 | 18,136
Nervous System 24 | 18,561
Skin and soft tissues 24 | 18,115
Blood and immune system 23 | 17,995
Cardiovascular System 23 | 17,958
Digestive Tract 23 | 18,473
Female tissues 23 | 18,647
Male tissues 23 | 17,969
Respiratory system 23 | 17,484
Urinary Tract 23 | 18,444

Target Family

Non-IDG 15 | 11,969
Transcription Factor 4 | 1,400
Enzyme 2 | 4,146
Kinase 2 | 634
GPCR 1 | 408

GO Process

positive regulation of smoothe... 24 | 24
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Indian hedgehog protein IHH Tbio Non-IDG -2.58713 390.9 314
Serine/threonine-protein kinase 36 STK36 Tbio Kinase -0.49449 1.15 117
Short stature homeobox protein 2 SHOX2 Tbio Transcription Factor -1.60365 43.1 94
Serine/threonine-protein kinase ULK3 ULK3 Tchem Kinase -0.81602 7.26 215