Development Level

Tchem 22 | 1,598
Tclin 19 | 613
Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
increased monocyte cell number 2 | 63
abnormal bone structure 1 | 187
abnormal eye anterior chamber ... 1 | 9
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
decreased body weight 1 | 161
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 41 | 11,493
Cancer 37 | 2,499
osteosarcoma 33 | 7,950
ovarian cancer 24 | 8,520
Blastic phase chronic myeloid leukemia 19 | 58
Chronic Myelocytic Leukemia Accelerated Phase 19 | 59
interstitial cystitis 19 | 2,312
psoriasis 19 | 6,694
glioblastoma 18 | 5,792
Chronic phase chronic myeloid leukemia 17 | 45
Kidney cancer 17 | 2,613
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 17 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 17 | 47
medulloblastoma, large-cell 17 | 6,241
lung cancer 16 | 4,740
non-small cell lung cancer 15 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung carcinoma 14 | 2,843
invasive ductal carcinoma 13 | 2,951
Breast cancer 11 | 3,578
atypical teratoid / rhabdoid tumor 11 | 5,112
diabetes mellitus 11 | 1,728
ependymoma 11 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
adult high grade glioma 10 | 3,801
cutaneous lupus erythematosus 10 | 1,057
malignant mesothelioma 10 | 3,232
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Astrocytoma, Pilocytic 9 | 3,081
Autosomal recessive predisposition 9 | 1,442
Rheumatoid arthritis 9 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
pancreatic cancer 9 | 2,398
primary Sjogren syndrome 9 | 735
subependymal giant cell astrocytoma 9 | 2,287
spina bifida 8 | 1,074
Melanoma 7 | 711
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
group 3 medulloblastoma 7 | 4,104
group 4 medulloblastoma 7 | 1,855
primitive neuroectodermal tumor 7 | 3,035
Alzheimer's disease 6 | 658
Chronic graft-versus-host disease 6 | 6
Chronic lymphoid leukemia, disease 6 | 13
Diarrhea 6 | 253
Immune system cancer 6 | 140
Lymphoid leukemia 6 | 160
Mantle cell lymphoma 6 | 23
Obesity 6 | 678
Pick disease 6 | 1,894
Renal Cell Carcinoma 6 | 214
Waldenström macroglobulinemia 6 | 6
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
Adenocarcinoma 5 | 122
Agammaglobulinemia 5 | 34
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Chronic Lymphocytic Leukemia 5 | 262
Failure to gain weight 5 | 365
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Mammary Neoplasms 5 | 425
Pediatric failure to thrive 5 | 365
Polycythemia vera 5 | 27
Skin cancer 5 | 469
cystic fibrosis 5 | 1,696
juvenile dermatomyositis 5 | 1,187
Anemia 4 | 365
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Carcinoma of thyroid 4 | 17
Down syndrome 4 | 499
Fatigue 4 | 182
Gastrointestinal stromal tumor 4 | 62
Heart disease 4 | 306
Immunologic Deficiency Syndromes 4 | 113
Kidney disease 4 | 430
Multiple myeloma 4 | 1,332
Neoplasm Invasiveness 4 | 161
Prostatic Neoplasms 4 | 495
Splenomegaly 4 | 190
Squamous cell carcinoma 4 | 129
Stomach Neoplasms 4 | 300
Systemic lupus erythematosus 4 | 194
Thrombocytopenia 4 | 197
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
facioscapulohumeral dystrophy 4 | 288
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
urothelial carcinoma 4 | 318
esophageal adenocarcinoma 3 | 737
mucosa-associated lymphoid tissue lymphoma 3 | 484
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Male tissues 47 | 17,142
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Blood and immune system 46 | 16,909
Liver and Pancreas 46 | 16,750
Nervous System 45 | 16,725
Cardiovascular System 44 | 15,192

Target Family

Kinase 42 | 634
Non-IDG 5 | 12,091

GO Process

peptidyl-tyrosine autophosphor... 47 | 47
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Tyrosine-protein kinase Tec TEC Tchem Kinase -0.75690 9.25 247
Tyrosine-protein kinase STYK1 STYK1 Tbio Kinase -2.33665 210.7 239
Non-receptor tyrosine-protein kinase TYK2 TYK2 Tclin Kinase -2.47105 252.9 547
Tyrosine-protein kinase CSK CSK Tchem Kinase -2.54736 271.3 547
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440