Development Level

Tbio 65 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal embryo size 3 | 220
abnormal eye morphology 3 | 68
abnormal neural tube closure 3 | 46
abnormal placenta size 3 | 20
embryonic growth retardation 3 | 106
impaired glucose tolerance 3 | 75
mammalian phenotype 3 | 17
pale yolk sac 3 | 25
prenatal lethality prior to he... 3 | 87
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal limb bud morphology 2 | 17
abnormal liver size 2 | 5
abnormal retina morphology 2 | 71
abnormal snout morphology 2 | 23
decreased body weight 2 | 161
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
increased body weight 2 | 25
increased total body fat amoun... 2 | 134
pale liver 2 | 6
pallor 2 | 34
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal locomotor activation 1 | 16
abnormal midbrain development 1 | 20
abnormal midbrain morphology 1 | 10
abnormal nail morphology 1 | 8
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal tail movements 1 | 12
abnormal urination 1 | 1
corneal opacity 1 | 32
curly tail 1 | 1
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
kinked tail 1 | 2
long tibia 1 | 25
mydriasis 1 | 6
prenatal lethality 1 | 28
prolonged QRS complex duration 1 | 8
short tibia 1 | 97

Disease

Carcinoma 60 | 11,493
ovarian cancer 43 | 8,520
osteosarcoma 42 | 7,950
psoriasis 42 | 6,694
atypical teratoid / rhabdoid tumor 36 | 5,112
Cancer 35 | 2,499
glioblastoma 32 | 5,792
ependymoma 28 | 4,679
group 3 medulloblastoma 27 | 4,104
medulloblastoma, large-cell 27 | 6,241
lung cancer 26 | 4,740
Kidney cancer 25 | 2,613
pancreatic cancer 23 | 2,398
lung adenocarcinoma 20 | 2,716
primitive neuroectodermal tumor 20 | 3,035
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Intellectual disability 18 | 1,016
malignant mesothelioma 18 | 3,232
Breast cancer 17 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Cleft Palate 16 | 271
Dull intelligence 16 | 645
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
astrocytic glioma 16 | 2,597
invasive ductal carcinoma 16 | 2,951
oligodendroglioma 15 | 2,850
Astrocytoma, Pilocytic 14 | 3,081
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
non-small cell lung cancer 14 | 2,890
Epilepsy 13 | 792
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
spina bifida 13 | 1,074
Autosomal recessive predisposition 12 | 1,442
Orbital separation excessive 12 | 244
interstitial cystitis 12 | 2,312
primary pancreatic ductal adenocarcinoma 12 | 1,109
subependymal giant cell astrocytoma 12 | 2,287
Short stature 11 | 531
breast carcinoma 11 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Cleft Lip 10 | 141
Muscle hypotonia 10 | 571
Rheumatoid arthritis 10 | 1,191
Seizures 10 | 596
diabetes mellitus 10 | 1,728
fibroadenoma 10 | 559
lung carcinoma 10 | 2,843
tuberculosis 10 | 2,010
Curvature of spine 9 | 282
Strabismus 9 | 270
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
Acquired scoliosis 8 | 281
Brachydactyly 8 | 156
Broad flat nasal bridge 8 | 236
Endometrial cancer 8 | 311
Hydrocephalus 8 | 152
Liver cancer 8 | 604
Nasal bridge wide 8 | 236
Pick disease 8 | 1,894
Polydactyly 8 | 107
Schizophrenia 8 | 1,160
astrocytoma 8 | 1,146
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Craniofacial Abnormalities 7 | 151
Hypertensive disease 7 | 292
Liver Cirrhosis, Experimental 7 | 769
Neural Tube Defects 7 | 31
Uranostaphyloschisis 7 | 167
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
Abnormally small eyeball 6 | 97
Agenesis of corpus callosum 6 | 83
Anencephaly 6 | 26
Cataract 6 | 297
Decreased size of eyeball 6 | 97
Dilated ventricles (finding) 6 | 121
Frontal bossing 6 | 157
Increase in blood pressure 6 | 119
Low set ears 6 | 181
Microphthalmos 6 | 100
Sensorineural Hearing Loss (disorder) 6 | 284
Small head 6 | 374
active Crohn's disease 6 | 922
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
atypical teratoid/rhabdoid tumor 6 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cutaneous lupus erythematosus 6 | 1,057
medulloblastoma 6 | 720
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064

Tissue

Endocrine System 75 | 18,159
Female tissues 74 | 17,400
Urinary Tract 74 | 16,678
Nervous System 73 | 16,725
Skin and soft tissues 73 | 17,230
Blood and immune system 72 | 16,909
Digestive Tract 72 | 17,369
Male tissues 72 | 17,142
Liver and Pancreas 71 | 16,750
Respiratory system 71 | 16,393
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 39 | 12,091
Transcription Factor 13 | 1,400
Enzyme 12 | 4,145
Epigenetic 3 | 242
GPCR 3 | 408
Kinase 3 | 634
Nuclear Receptor 2 | 48

GO Process

neural tube closure 75 | 75
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil and C2 domain-containing protein 2A CC2D2A Tbio Non-IDG -1.23748 18.2 17
SCL-interrupting locus protein STIL Tbio Non-IDG -1.99386 94.6 49
Deformed epidermal autoregulatory factor 1 homolog DEAF1 Tbio Transcription Factor -1.70929 51.9 248
AT-rich interactive domain-containing protein 1A ARID1A Tbio Transcription Factor -2.61778 423.3 132
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.97029 90.6 101
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Histone acetyltransferase KAT2A KAT2A Tbio Epigenetic -2.46487 271.9 262
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474
Intraflagellar transport protein 172 homolog IFT172 Tbio Non-IDG -2.51329 317.3 69
Prickle-like protein 1 PRICKLE1 Tbio Non-IDG -1.31805 20.0 115