Development Level

Tbio 70 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
embryonic lethality prior to t... 5 | 278
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased bone mineral content 2 | 151
embryonic lethality prior to o... 2 | 239
impaired pupillary reflex 2 | 26
increased circulating choleste... 2 | 66
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating sodium l... 1 | 22
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased heart left ventricle... 1 | 4
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
male infertility 1 | 123
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 48 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 33 | 7,950
lung cancer 29 | 4,740
medulloblastoma, large-cell 29 | 6,241
Cancer 26 | 2,499
glioblastoma 25 | 5,792
psoriasis 25 | 6,694
Breast cancer 23 | 3,578
ependymoma 23 | 4,679
atypical teratoid / rhabdoid tumor 21 | 5,112
group 3 medulloblastoma 21 | 4,104
invasive ductal carcinoma 20 | 2,951
lung adenocarcinoma 19 | 2,716
malignant mesothelioma 19 | 3,232
non-small cell lung cancer 19 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Kidney cancer 16 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
adult high grade glioma 15 | 3,801
astrocytic glioma 14 | 2,597
diabetes mellitus 14 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
breast carcinoma 13 | 1,638
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 13 | 3,035
Cleft Palate 12 | 271
Multiple myeloma 12 | 1,332
ductal carcinoma in situ 12 | 1,745
lung carcinoma 12 | 2,843
pancreatic cancer 12 | 2,398
Astrocytoma, Pilocytic 11 | 3,081
Autosomal recessive predisposition 11 | 1,442
Pick disease 11 | 1,894
colon cancer 11 | 1,478
Cleft Lip 10 | 141
Cryptorchidism 10 | 296
astrocytoma 10 | 1,146
cystic fibrosis 10 | 1,696
interstitial cystitis 10 | 2,312
pituitary cancer 10 | 1,972
Depressive disorder 9 | 409
Orbital separation excessive 9 | 244
Short stature 9 | 531
ulcerative colitis 9 | 1,819
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Intellectual disability 8 | 1,016
Mental and motor retardation 8 | 608
Rheumatoid arthritis 8 | 1,191
juvenile dermatomyositis 8 | 1,187
progressive supranuclear palsy 8 | 676
subependymal giant cell astrocytoma 8 | 2,287
Achondroplasia 7 | 21
Craniosynostosis 7 | 74
Delayed bone age 7 | 136
Downward slant of palpebral fissure 7 | 158
Dull intelligence 7 | 645
Hypoplastic mandible condyle 7 | 275
Low intelligence 7 | 645
Mandibular hypoplasia 7 | 275
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Micrognathism 7 | 275
Osteoporosis 7 | 363
Poor school performance 7 | 645
dermatomyositis 7 | 966
group 4 medulloblastoma 7 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Bipolar Disorder 6 | 666
Blepharoptosis 6 | 231
Congenital Epicanthus 6 | 177
Congenital hypoplasia of penis 6 | 176
Decreased fertility 6 | 33
Delayed Puberty 6 | 97
Epilepsy 6 | 792
Fetal Growth Retardation 6 | 189
Hypogonadism, Isolated Hypogonadotropic 6 | 71
Hypogonadotropic hypogonadism 6 | 89
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
LADD syndrome 6 | 9
Low set ears 6 | 181
Lung Neoplasms 6 | 232
Mental Depression 6 | 333
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
Seizures 6 | 596
Sense of smell impaired 6 | 21
Strabismus 6 | 270
Waldenstrons macroglobulinemia 6 | 765
Wide spaced nipples 6 | 46
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
tuberculosis 6 | 2,010
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510

Tissue

Endocrine System 81 | 18,159
Nervous System 80 | 16,725
Digestive Tract 79 | 17,369
Female tissues 79 | 17,400
Urinary Tract 79 | 16,678
Blood and immune system 78 | 16,909
Male tissues 78 | 17,142
Skin and soft tissues 78 | 17,230
Liver and Pancreas 77 | 16,750
Respiratory system 76 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 22 | 4,145
Kinase 6 | 634

GO Process

fibroblast growth factor recep... 82 | 82
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
General transcription factor IIF subunit 2 GTF2F2 Tbio Non-IDG -1.55064 36.2 192
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Anosmin-1 ANOS1 Tbio Non-IDG -2.64038 424.6 155
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.93963 79.1 299
Fibroblast growth factor 20 FGF20 Tbio Non-IDG -1.71980 55.3 117
Protocadherin Fat 4 FAT4 Tbio Non-IDG -1.70369 49.6 50