Development Level

Tbio 19 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
osteosarcoma 12 | 7,950
medulloblastoma, large-cell 11 | 6,241
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 9 | 5,112
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pancreatic cancer 8 | 2,398
Kidney cancer 7 | 2,613
Breast cancer 6 | 3,578
astrocytic glioma 6 | 2,597
ependymoma 6 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
subependymal giant cell astrocytoma 6 | 2,287
Amyotrophic lateral sclerosis 5 | 451
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
Cancer 4 | 2,499
Cardiomyopathy, Dilated 4 | 83
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
nasopharyngeal carcinoma 4 | 1,058
Cardiomyopathy 3 | 116
Congestive heart failure 3 | 113
Creatine phosphokinase serum increased 3 | 110
Decreased tendon reflex 3 | 122
Dilated cardiomyopathy 3 | 56
Disease Models, Animal 3 | 155
Duchenne muscular dystrophy 3 | 601
Elevated creatine kinase 3 | 110
Familial isolated dilated cardiomyopathy 3 | 41
Gowers sign 3 | 24
Gowers sign present 3 | 24
Hypertension 3 | 396
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
Lymphoid leukemia 3 | 160
Melanoma 3 | 711
Muscle hypotonia 3 | 571
Myopathy 3 | 185
Obesity 3 | 678
Proteinuria 3 | 144
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
Waddling gait 3 | 34
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acquired scoliosis 2 | 281
Attention deficit hyperactivity disorder 2 | 278
Curvature of spine 2 | 282
Dementia 2 | 175
Diarrhea 2 | 253
Endometrial cancer 2 | 311
Kidney Failure 2 | 111
Kidney disease 2 | 430
Liver cancer 2 | 604
Mental Depression 2 | 333
Neoplasm Invasiveness 2 | 161
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Reflex, Deep Tendon, Absent 2 | 92
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 21 | 18,159
Liver and Pancreas 21 | 16,750
Urinary Tract 21 | 16,678
Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230

Target Family

Non-IDG 16 | 12,091
Enzyme 3 | 4,145
Ion Channel 1 | 344
Transporter 1 | 473

GO Function

myosin binding 21 | 21
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRIM32 TRIM32 Tbio Enzyme -1.92209 86.4 142