Development Level

Tbio 47 | 11,445
Tchem 15 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased vertical activity 4 | 208
abnormal heart morphology 3 | 162
abnormal sleep behavior 3 | 70
abnormal testis morphology 3 | 43
decreased grip strength 3 | 116
enlarged heart 3 | 210
hypoactivity 3 | 132
increased bone mineral content 3 | 108
preweaning lethality, complete... 3 | 979
abnormal liver morphology 2 | 17
abnormal lung morphology 2 | 26
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
hemorrhage 2 | 23
impaired righting response 2 | 26
increased total body fat amoun... 2 | 134
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
aorta stenosis 1 | 2
cataract 1 | 92
cleft palate 1 | 8
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged liver 1 | 2
enlarged testis 1 | 6
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
short tibia 1 | 97
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
trunk curl 1 | 16

Disease

psoriasis 40 | 6,694
Carcinoma 37 | 11,493
osteosarcoma 33 | 7,950
glioblastoma 32 | 5,792
lung cancer 28 | 4,740
ovarian cancer 28 | 8,520
adult high grade glioma 27 | 3,801
Cancer 25 | 2,499
atypical teratoid / rhabdoid tumor 25 | 5,112
Astrocytoma, Pilocytic 24 | 3,081
ependymoma 24 | 4,679
lung carcinoma 24 | 2,843
medulloblastoma, large-cell 24 | 6,241
lung adenocarcinoma 19 | 2,716
Schizophrenia 18 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Breast cancer 17 | 3,578
diabetes mellitus 17 | 1,728
non-small cell lung cancer 17 | 2,890
oligodendroglioma 17 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
pancreatic cancer 16 | 2,398
tuberculosis 16 | 2,010
Atopic dermatitis 15 | 952
group 3 medulloblastoma 15 | 4,104
interstitial cystitis 15 | 2,312
malignant mesothelioma 15 | 3,232
pituitary cancer 15 | 1,972
Hypertension 14 | 396
cystic fibrosis 14 | 1,696
invasive ductal carcinoma 14 | 2,951
Pick disease 13 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Bipolar Disorder 12 | 666
astrocytic glioma 12 | 2,597
subependymal giant cell astrocytoma 12 | 2,287
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Depressive disorder 11 | 409
Hypertensive disease 11 | 292
primitive neuroectodermal tumor 11 | 3,035
Asthma 10 | 385
Atherosclerosis 10 | 291
Kidney disease 10 | 430
group 4 medulloblastoma 10 | 1,855
Arthritis 9 | 290
Diarrhea 9 | 253
Mental Depression 9 | 333
Obesity 9 | 678
adrenocortical carcinoma 9 | 1,428
cutaneous lupus erythematosus 9 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Cerebrovascular disease 8 | 238
Coronary artery disease 8 | 268
Endometriosis 8 | 540
Kidney cancer 8 | 2,613
Lung disease 8 | 142
Major Depressive Disorder 8 | 301
Multiple myeloma 8 | 1,332
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
esophageal adenocarcinoma 8 | 737
nasopharyngeal carcinoma 8 | 1,058
Alcoholic Intoxication, Chronic 7 | 289
Alzheimer's disease 7 | 658
Anemia 7 | 365
Autistic Disorder 7 | 364
Inflammation 7 | 120
Osteoporosis 7 | 363
Seizures 7 | 596
active ulcerative colitis 7 | 764
breast carcinoma 7 | 1,638
gastric cancer 7 | 459
hepatocellular carcinoma 7 | 547
primary pancreatic ductal adenocarcinoma 7 | 1,109
Fever 6 | 138
Heart disease 6 | 306
Heart failure 6 | 162
Hypersensitivity reaction type II disease 6 | 253
Hypotension 6 | 82
Liver Cirrhosis 6 | 181
Liver Cirrhosis, Experimental 6 | 769
Multiple Sclerosis 6 | 540
Neurodegenerative disease 6 | 414
Rheumatoid arthritis 6 | 1,191
Unipolar Depression 6 | 250
Waldenstrons macroglobulinemia 6 | 765
active Crohn's disease 6 | 922
aldosterone-producing adenoma 6 | 665
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
pediatric high grade glioma 6 | 1,064
Down syndrome 5 | 499
Epilepsy 5 | 792
Reperfusion Injury 5 | 86
acute myeloid leukemia 5 | 783
dermatomyositis 5 | 966
head and neck cancer 5 | 271
pancreatic carcinoma 5 | 562
periodontitis 5 | 293
spina bifida 5 | 1,074

Tissue

Endocrine System 67 | 18,159
Digestive Tract 66 | 17,369
Skin and soft tissues 66 | 17,230
Female tissues 65 | 17,400
Urinary Tract 65 | 16,678
Liver and Pancreas 64 | 16,750
Male tissues 64 | 17,142
Blood and immune system 63 | 16,909
Nervous System 63 | 16,725
Respiratory system 61 | 16,393
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 25 | 4,145
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GO Component

secretory granule 69 | 69
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neutrophil elastase ELANE Tclin Enzyme -3.61753 3958.4 411
Tissue-type plasminogen activator PLAT Tclin Enzyme -3.71677 5819.3 555
C-type natriuretic peptide NPPC Tbio Non-IDG -2.91034 740.1 175
Zinc transporter 5 SLC30A5 Tbio Transporter -1.39046 25.7 29
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.88342 751.2 143