Development Level

Tbio 610 | 11,445
Tchem 91 | 1,598
Tdark 62 | 6,588
Tclin 38 | 613

Collection

GPCR: IDG Consortium (Targets) 7 | 126
Ion Channel: IDG Consortium (T... 6 | 99
GPCR: IDG Consortium (Complete... 3 | 25
Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 46 | 979
preweaning lethality, incomple... 21 | 499
embryonic lethality prior to t... 18 | 278
decreased total body fat amoun... 13 | 207
embryonic lethality prior to o... 13 | 239
abnormal behavior 11 | 298
decreased vertical activity 10 | 208
increased mean corpuscular vol... 9 | 92
abnormal embryo size 8 | 220
abnormal lens morphology 8 | 81
decreased bone mineral content 8 | 151
increased circulating sodium l... 8 | 71
increased lean body mass 8 | 172
short tibia 8 | 97
abnormal sleep behavior 7 | 70
cataract 7 | 92
decreased bone mineral density 7 | 126
decreased circulating serum al... 7 | 82
decreased grip strength 7 | 116
hyperactivity 7 | 148
increased bone mineral content 7 | 108
increased mean corpuscular hem... 7 | 96
abnormal kidney morphology 6 | 65
abnormal retina morphology 6 | 71
abnormal seminal vesicle morph... 6 | 114
edema 6 | 59
enlarged heart 6 | 210
enlarged lymph nodes 6 | 37
hypoactivity 6 | 132
increased circulating alkaline... 6 | 122
abnormal behavioral response t... 5 | 66
abnormal bone structure 5 | 187
cardiovascular system phenotyp... 5 | 36
decreased body length 5 | 101
decreased body weight 5 | 161
decreased circulating HDL chol... 5 | 68
decreased circulating LDL chol... 5 | 38
decreased circulating choleste... 5 | 93
decreased circulating triglyce... 5 | 79
decreased lymphocyte cell numb... 5 | 83
decreased mean corpuscular hem... 5 | 50
increased circulating chloride... 5 | 41
increased total body fat amoun... 5 | 134
abnormal heart morphology 4 | 162
abnormal limb bud morphology 4 | 17
abnormal limb morphology 4 | 13
decreased circulating glucose ... 4 | 126
decreased circulating insulin ... 4 | 76
decreased fasted circulating g... 4 | 65
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
embryonic growth retardation 4 | 106
hydrometra 4 | 53
impaired glucose tolerance 4 | 75
increased bone mineral density 4 | 72
increased circulating potassiu... 4 | 29
increased monocyte cell number 4 | 63
persistence of hyaloid vascula... 4 | 33
small superior vagus ganglion 4 | 74
abnormal coat appearance 3 | 31
abnormal coat-hair pigmentatio... 3 | 64
abnormal embryo turning 3 | 31
abnormal eye morphology 3 | 68
abnormal facial morphology 3 | 17
abnormal gait 3 | 69
abnormal pericardium morpholog... 3 | 26
abnormal skin morphology 3 | 50
decreased caudal vertebrae num... 3 | 53
decreased circulating alanine ... 3 | 47
decreased mean corpuscular hem... 3 | 31
hemorrhage 3 | 23
impaired pupillary reflex 3 | 26
improved glucose tolerance 3 | 79
increased circulating aspartat... 3 | 15
increased circulating choleste... 3 | 66
increased circulating free fat... 3 | 20
increased circulating total pr... 3 | 28
increased circulating triglyce... 3 | 42
increased hematocrit 3 | 46
increased leukocyte cell numbe... 3 | 47
increased mean corpuscular hem... 3 | 36
increased neutrophil cell numb... 3 | 46
increased or absent threshold ... 3 | 101
increased startle reflex 3 | 112
pallor 3 | 34
prenatal lethality 3 | 28
small testis 3 | 58
thrombocytosis 3 | 27
tremors 3 | 39
abnormal epididymis morphology 2 | 42
abnormal liver morphology 2 | 17
abnormal lung morphology 2 | 26
decreased circulating bilirubi... 2 | 19
decreased heart rate variabili... 2 | 13
decreased neutrophil cell numb... 2 | 42
enlarged urinary bladder 2 | 8
increased body weight 2 | 25
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 76
microphthalmia 2 | 26

Disease

Carcinoma 498 | 11,493
ovarian cancer 398 | 8,520
osteosarcoma 377 | 7,950
psoriasis 346 | 6,694
glioblastoma 324 | 5,792
medulloblastoma, large-cell 302 | 6,241
atypical teratoid / rhabdoid tumor 253 | 5,112
lung cancer 232 | 4,740
ependymoma 225 | 4,679
lung carcinoma 216 | 2,843
Astrocytoma, Pilocytic 214 | 3,081
adult high grade glioma 212 | 3,801
Cancer 211 | 2,499
malignant mesothelioma 173 | 3,232
Breast cancer 167 | 3,578
diabetes mellitus 162 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 159 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 159 | 3,291
invasive ductal carcinoma 156 | 2,951
group 3 medulloblastoma 154 | 4,104
tuberculosis 154 | 2,010
non-small cell lung cancer 153 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 152 | 2,989
interstitial cystitis 150 | 2,312
lung adenocarcinoma 146 | 2,716
oligodendroglioma 146 | 2,850
pancreatic cancer 143 | 2,398
subependymal giant cell astrocytoma 141 | 2,287
primitive neuroectodermal tumor 140 | 3,035
astrocytic glioma 132 | 2,597
Kidney cancer 121 | 2,613
Rheumatoid arthritis 113 | 1,191
Pick disease 106 | 1,894
ulcerative colitis 106 | 1,819
dermatomyositis 102 | 966
group 4 medulloblastoma 98 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 96 | 1,962
cutaneous lupus erythematosus 89 | 1,057
Autosomal recessive predisposition 87 | 1,442
Schizophrenia 87 | 1,160
Multiple myeloma 86 | 1,332
pituitary cancer 86 | 1,972
juvenile dermatomyositis 83 | 1,187
Hypersensitivity reaction type II disease 81 | 253
cystic fibrosis 80 | 1,696
astrocytoma 78 | 1,146
primary pancreatic ductal adenocarcinoma 78 | 1,109
Ankylosing spondylitis 76 | 140
breast carcinoma 75 | 1,638
Arthritis 74 | 290
ductal carcinoma in situ 74 | 1,745
Behcet's disease 70 | 89
Liver Cirrhosis, Experimental 68 | 769
acute quadriplegic myopathy 68 | 1,158
mucosa-associated lymphoid tissue lymphoma 66 | 484
adrenocortical carcinoma 64 | 1,428
gastric carcinoma 63 | 807
Human immunodeficiency virus infectious disease 62 | 138
Juvenile rheumatoid arthritis 62 | 111
Multiple Sclerosis 62 | 540
colon cancer 62 | 1,478
Acquired immunodeficiency syndrome 61 | 197
Bipolar Disorder 59 | 666
Kidney disease 59 | 430
Uveitis 58 | 103
Herpes zoster 57 | 68
spina bifida 57 | 1,074
pediatric high grade glioma 56 | 1,064
Duchenne muscular dystrophy 55 | 601
esophageal adenocarcinoma 54 | 737
Melanoma 53 | 711
Psoriatic arthritis 53 | 86
Epilepsy 52 | 792
Alzheimer's disease 51 | 658
Stevens-Johnson syndrome 51 | 92
Anemia 50 | 365
active Crohn's disease 49 | 922
Waldenstrons macroglobulinemia 48 | 765
primary Sjogren syndrome 48 | 735
Dermatitis 46 | 157
Intellectual disability 46 | 1,016
non primary Sjogren syndrome sicca 43 | 891
Skin cancer 42 | 469
active ulcerative colitis 42 | 764
nasopharyngeal carcinoma 42 | 1,058
Liver cancer 41 | 604
acute myeloid leukemia 41 | 783
Parkinson's disease 40 | 392
Synovitis 38 | 78
Down syndrome 37 | 499
Nephritis 37 | 51
Neurodegenerative disease 37 | 414
autosomal dominant Emery-Dreifuss muscular dystrophy 37 | 510
Atopic dermatitis 36 | 952
Congenital adrenal hyperplasia 36 | 73
Liver disease 36 | 237
Takayasu's arteritis 36 | 53
aldosterone-producing adenoma 36 | 665
Prostatic Neoplasms 35 | 495
drug-induced hepatitis 35 | 44

Tissue

Endocrine System 711 | 18,159
Digestive Tract 703 | 17,369
Female tissues 701 | 17,400
Skin and soft tissues 696 | 17,230
Male tissues 691 | 17,142
Liver and Pancreas 689 | 16,750
Blood and immune system 687 | 16,909
Nervous System 685 | 16,725
Urinary Tract 680 | 16,678
Respiratory system 674 | 16,393
Cardiovascular System 629 | 15,192

Target Family

Non-IDG 517 | 12,091
Enzyme 164 | 4,145
Transporter 34 | 473
Ion Channel 32 | 344
GPCR 27 | 408
Kinase 18 | 634
Transcription Factor 4 | 1,400
oGPCR 4 | 421
Epigenetic 1 | 242

Compartment GO Term

Vesicle membrane 801 | 801
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 225 TMEM225 Tdark Non-IDG -0.19781 1.99 3
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Sorting nexin-18 SNX18 Tbio Non-IDG -0.76724 7.20 156
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Small cell adhesion glycoprotein SMAGP Tdark Non-IDG -0.06695 1.95 82
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Putative synaptogyrin-2 like protein N/A Tdark Non-IDG -0.69433 7.83 0
Ras-related protein Rab-39A RAB39A Tdark Enzyme -0.57787 3.49 68
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209