Development Level

Tbio 126 | 10,625
Tchem 33 | 1,890
Tdark 17 | 7,003
Tclin 9 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased body weight 6 | 174
decreased lean body mass 6 | 195
decreased heart weight 5 | 44
hypoactivity 5 | 89
increased mean corpuscular hem... 5 | 93
preweaning lethality, complete... 5 | 633
decreased body length 4 | 108
decreased bone mineral content 4 | 157
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased total body fat amoun... 4 | 186
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
increased heart weight 3 | 37
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal lens morphology 2 | 73
abnormal tibia morphology 2 | 14
decreased circulating LDL chol... 2 | 37
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased startle reflex 2 | 48
decreased total retina thickne... 2 | 20
decreased vertical activity 2 | 22
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased lean body mass 2 | 107
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 5
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal tail morphology 1 | 17
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
absent vibrissae 1 | 14
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
edema 1 | 11
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
hydrops fetalis 1 | 22
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11

Disease

ovarian cancer 104 | 8,484
osteosarcoma 80 | 7,933
medulloblastoma, large-cell 76 | 6,234
lung cancer 69 | 4,466
psoriasis 67 | 6,685
glioblastoma 63 | 5,572
atypical teratoid / rhabdoid tumor 54 | 4,369
malignant mesothelioma 43 | 3,162
invasive ductal carcinoma 42 | 2,950
Cancer 37 | 2,346
pilocytic astrocytoma 34 | 3,086
non-small cell lung cancer 32 | 2,798
ependymoma 31 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
oligodendroglioma 31 | 2,849
Pick disease 30 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
ulcerative colitis 29 | 2,087
astrocytic glioma 28 | 2,241
ductal carcinoma in situ 28 | 1,745
lung adenocarcinoma 28 | 2,713
pediatric high grade glioma 28 | 2,712
Breast cancer 27 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
lung carcinoma 27 | 2,844
pancreatic cancer 27 | 2,300
primitive neuroectodermal tumor 27 | 3,031
Multiple myeloma 25 | 1,327
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
adult high grade glioma 24 | 2,148
Alzheimer's disease 23 | 644
group 4 medulloblastoma 23 | 1,875
pituitary cancer 22 | 1,972
Neurodegenerative disease 21 | 383
breast carcinoma 21 | 1,614
diabetes mellitus 21 | 1,663
sonic hedgehog group medulloblastoma 20 | 1,482
colon cancer 19 | 1,475
interstitial cystitis 19 | 2,299
subependymal giant cell astrocytoma 19 | 2,287
tuberculosis 18 | 1,557
Obesity 17 | 616
astrocytoma 17 | 1,493
dermatomyositis 17 | 933
medulloblastoma 17 | 1,524
group 3 medulloblastoma 16 | 2,254
aldosterone-producing adenoma 15 | 664
posterior fossa group A ependymoma 15 | 1,511
posterior fossa group B ependymoma 15 | 1,530
Carcinoma 14 | 2,147
Rheumatoid Arthritis 14 | 1,160
Parkinson's disease 13 | 364
acute quadriplegic myopathy 13 | 1,157
adrenocortical carcinoma 13 | 1,427
tuberculosis and treatment for 6 months 13 | 686
Waldenstrons macroglobulinemia 12 | 765
esophageal adenocarcinoma 12 | 737
juvenile dermatomyositis 12 | 1,189
primary pancreatic ductal adenocarcinoma 12 | 1,271
progressive supranuclear palsy 12 | 674
active Crohn's disease 11 | 918
cystic fibrosis 11 | 1,665
hereditary spastic paraplegia 11 | 313
primary Sjogren syndrome 11 | 789
Atopic dermatitis 10 | 944
Chronic Lymphocytic Leukemia 10 | 242
Toxic encephalopathy 10 | 131
cutaneous lupus erythematosus 10 | 1,056
nasopharyngeal carcinoma 10 | 1,056
non primary Sjogren syndrome sicca 10 | 840
Mammary Neoplasms 9 | 410
Optic atrophy 9 | 43
Polycystic Ovary Syndrome 9 | 332
acute myeloid leukemia 9 | 780
gastric carcinoma 9 | 832
Autistic Disorder 8 | 320
Diabetes Mellitus, Experimental 8 | 106
Multiple Sclerosis 8 | 498
Vascular disease 8 | 281
atypical teratoid/rhabdoid tumor 8 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
spina bifida 8 | 1,064
Endometriosis 7 | 535
chronic rhinosinusitis 7 | 512
gastric cancer 7 | 430
pancreatic carcinoma 7 | 567
Amyotrophic Lateral Sclerosis 6 | 431
COPD 6 | 113
Cardiomyopathy 6 | 110
Down syndrome 6 | 548
Duchenne muscular dystrophy 6 | 602
IGA Glomerulonephritis 6 | 454
Liver carcinoma 6 | 217
Myocardial Ischemia 6 | 169
Nerve Degeneration 6 | 73
Prostatic Neoplasms 6 | 471
active ulcerative colitis 6 | 477
fibroadenoma 6 | 557
mucosa-associated lymphoid tissue lymphoma 6 | 480
tuberculosis and treatment for 3 months 6 | 327

Tissue

Nervous System 184 | 18,561
Blood and immune system 183 | 17,995
Digestive Tract 183 | 18,473
Female tissues 183 | 18,647
Liver and Pancreas 183 | 18,136
Urinary Tract 183 | 18,444
Cardiovascular System 182 | 17,958
Endocrine System 182 | 18,512
Male tissues 182 | 17,969
Respiratory system 181 | 17,484
Skin and soft tissues 181 | 18,115

Target Family

Non-IDG 108 | 11,971
Enzyme 51 | 4,146
Kinase 14 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 406
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Organelle outer membrane 185 | 185
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein misato homolog 1 MSTO1 Tdark Non-IDG -1.74451 53.5 48
Protein BTG4 BTG4 Tbio Non-IDG -1.03008 11.6 80
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.95326 94.6 135
Nesprin-2 SYNE2 Tbio Non-IDG -2.51721 337.2 32
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.83623 72.3 120
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.50852 352.2 235
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -0.77521 8.18 110
Mitochondrial import inner membrane translocase subunit TIM50 TIMM50 Tbio Enzyme -1.36611 26.4 120
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.44282 314.5 282
Mitoguardin 1 MIGA1 Tbio Non-IDG -0.83091 6.51 21