Development Level

Tbio 275 | 11,445
Tchem 57 | 1,598
Tdark 45 | 6,588
Tclin 19 | 613

IMPC Phenotype

preweaning lethality, complete... 45 | 979
embryonic lethality prior to t... 19 | 278
embryonic lethality prior to o... 18 | 239
preweaning lethality, incomple... 15 | 499
abnormal behavior 8 | 298
increased startle reflex 8 | 112
abnormal bone structure 7 | 187
abnormal embryo size 6 | 220
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
male infertility 6 | 123
abnormal embryo turning 4 | 31
decreased body weight 4 | 161
decreased bone mineral content 4 | 151
decreased circulating glucose ... 4 | 126
embryonic growth retardation 4 | 106
female infertility 4 | 60
increased bone mineral content 4 | 108
increased bone mineral density 4 | 72
increased mean corpuscular vol... 4 | 92
abnormal eye morphology 3 | 68
abnormal seminal vesicle morph... 3 | 114
abnormal spleen morphology 3 | 55
cardiovascular system phenotyp... 3 | 36
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased mean corpuscular vol... 3 | 79
decreased prepulse inhibition 3 | 82
enlarged heart 3 | 210
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
prenatal lethality prior to he... 3 | 87
small spleen 3 | 19
small testis 3 | 58
abnormal blood vessel morpholo... 2 | 5
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
absent pinna reflex 2 | 23
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
edema 2 | 59
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
pale yolk sac 2 | 25
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased circulating creatine... 1 | 4
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased mean corpuscular hem... 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired righting response 1 | 26
increased body length 1 | 32
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 247 | 11,493
ovarian cancer 216 | 8,520
osteosarcoma 193 | 7,950
lung cancer 161 | 4,740
medulloblastoma, large-cell 161 | 6,241
psoriasis 161 | 6,694
glioblastoma 158 | 5,792
Cancer 149 | 2,499
group 3 medulloblastoma 141 | 4,104
atypical teratoid / rhabdoid tumor 138 | 5,112
Breast cancer 124 | 3,578
malignant mesothelioma 120 | 3,232
primitive neuroectodermal tumor 103 | 3,035
non-small cell lung cancer 93 | 2,890
ependymoma 86 | 4,679
lung adenocarcinoma 82 | 2,716
Kidney cancer 80 | 2,613
adult high grade glioma 79 | 3,801
invasive ductal carcinoma 78 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 77 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 68 | 2,989
breast carcinoma 60 | 1,638
Multiple myeloma 56 | 1,332
ductal carcinoma in situ 55 | 1,745
colon cancer 52 | 1,478
pancreatic cancer 52 | 2,398
oligodendroglioma 51 | 2,850
Intellectual disability 50 | 1,016
adrenocortical carcinoma 49 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,955
astrocytic glioma 42 | 2,597
Schizophrenia 39 | 1,160
astrocytoma 39 | 1,146
diabetes mellitus 39 | 1,728
Astrocytoma, Pilocytic 38 | 3,081
Short stature 38 | 531
pituitary cancer 38 | 1,972
subependymal giant cell astrocytoma 38 | 2,287
Pick disease 37 | 1,894
ulcerative colitis 37 | 1,819
Dull intelligence 36 | 645
Low intelligence 36 | 645
Mental Retardation 36 | 645
Mental deficiency 36 | 645
Poor school performance 36 | 645
Waldenstrons macroglobulinemia 36 | 765
group 4 medulloblastoma 36 | 1,855
nasopharyngeal carcinoma 36 | 1,058
Autosomal recessive predisposition 34 | 1,442
Rheumatoid arthritis 34 | 1,191
Small head 34 | 374
pediatric high grade glioma 34 | 1,064
tuberculosis 34 | 2,010
lung carcinoma 33 | 2,843
Breast Neoplasms 32 | 445
Mammary Neoplasms 32 | 425
acute quadriplegic myopathy 32 | 1,158
Endometriosis 31 | 540
dermatomyositis 31 | 966
juvenile dermatomyositis 31 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Cognitive delay 30 | 608
Cryptorchidism 30 | 296
Global developmental delay 30 | 608
Mental and motor retardation 30 | 608
Prostatic Neoplasms 30 | 495
interstitial cystitis 30 | 2,312
Atopic dermatitis 27 | 952
acute myeloid leukemia 26 | 783
Epilepsy 25 | 792
Melanoma 25 | 711
non primary Sjogren syndrome sicca 25 | 891
Fetal Growth Retardation 23 | 189
Infant, Small for Gestational Age 23 | 176
Intrauterine retardation 23 | 176
Muscle hypotonia 23 | 571
Seizures 23 | 596
hepatocellular carcinoma 23 | 547
pancreatic carcinoma 23 | 562
Fanconi anemia 22 | 56
Liver cancer 22 | 604
Hypoplastic mandible condyle 21 | 275
Mandibular hypoplasia 21 | 275
Micrognathism 21 | 275
Stomach Neoplasms 21 | 300
medulloblastoma 21 | 720
Obesity 20 | 678
Microcephaly 19 | 166
cystic fibrosis 19 | 1,696
gastric cancer 19 | 459
primary Sjogren syndrome 19 | 735
spina bifida 19 | 1,074
Colorectal Neoplasms 18 | 243
Male infertility 18 | 206
Strabismus 18 | 270
aldosterone-producing adenoma 18 | 665
non-small cell lung carcinoma 18 | 317
Acquired scoliosis 17 | 281
Curvature of spine 17 | 282
cutaneous lupus erythematosus 17 | 1,057

Tissue

Endocrine System 392 | 18,159
Digestive Tract 385 | 17,369
Female tissues 384 | 17,400
Skin and soft tissues 383 | 17,230
Male tissues 380 | 17,142
Blood and immune system 379 | 16,909
Liver and Pancreas 374 | 16,750
Nervous System 371 | 16,725
Urinary Tract 371 | 16,678
Respiratory system 370 | 16,393
Cardiovascular System 359 | 15,192

Target Family

Non-IDG 213 | 12,091
Transcription Factor 67 | 1,400
Enzyme 51 | 4,145
Epigenetic 45 | 242
Kinase 11 | 634
Nuclear Receptor 8 | 48
Transporter 1 | 473

Compartment GO Term

Nuclear chromosome part 396 | 396
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.68275 4.92 168
Histone H1.2 HIST1H1C Tbio Non-IDG -2.01718 95.3 142
Histone H1.3 HIST1H1D Tbio Non-IDG -1.83212 63.8 66
Histone H1.5 HIST1H1B Tbio Non-IDG -2.13224 134.1 103
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 24
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69