Development Level

Tclin 48 | 602
Tbio 45 | 10,625
Tdark 12 | 7,003
Tchem 9 | 1,890

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 5 | 148
abnormal embryo size 3 | 112
embryonic lethality prior to t... 3 | 187
pallor 3 | 13
abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
abnormal skin coloration 2 | 18
embryonic growth retardation 2 | 28
increased exploration in new e... 2 | 56
abnormal QRS complex 1 | 25
abnormal embryo turning 1 | 15
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal skin appearance 1 | 8
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 2
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
hypoactivity 1 | 89
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
pale liver 1 | 5
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 62 | 8,492
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
Multiple myeloma 39 | 1,328
Leigh disease 38 | 81
osteosarcoma 36 | 7,933
psoriasis 31 | 6,685
lung cancer 27 | 4,473
Leigh syndrome 25 | 34
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Mitochondrial complex I deficiency 23 | 37
glioblastoma 22 | 5,572
Mitochondrial Complex 1 Deficiency 21 | 28
medulloblastoma, large-cell 20 | 6,234
astrocytic glioma 19 | 2,241
atypical teratoid / rhabdoid tumor 18 | 4,369
ependymoma 18 | 2,514
diabetes mellitus 16 | 1,663
NADH:Q(1) Oxidoreductase deficiency 15 | 20
Cancer 13 | 2,346
astrocytoma 13 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
Waldenstrons macroglobulinemia 12 | 765
Lactic acidosis 11 | 43
Leber hereditary optic neuropathy 11 | 17
cytochrome-c oxidase deficiency disease 11 | 19
oligodendroglioma 11 | 2,849
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY 10 | 14
Obesity 10 | 616
lung adenocarcinoma 10 | 2,714
Breast cancer 9 | 3,099
Cytochrome-c Oxidase Deficiency 9 | 15
Leber's optic atrophy 9 | 10
Mitochondrial myopathy 9 | 24
Optic Atrophy, Hereditary, Leber 9 | 14
Pick disease 9 | 1,893
medulloblastoma 9 | 1,524
non primary Sjogren syndrome sicca 9 | 840
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 8 | 9
acute myeloid leukemia 8 | 785
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
malignant mesothelioma 8 | 3,163
pediatric high grade glioma 8 | 2,712
ulcerative colitis 8 | 2,087
Neurodegenerative disease 7 | 383
adult high grade glioma 7 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
Anemia 6 | 252
Mitochondrial complex IV deficiency 6 | 6
Neoplastic Syndromes, Hereditary 6 | 48
Neuropathy 6 | 210
Paraganglioma 6 | 12
Parkinson's disease 6 | 364
Persistent generalized lymphadenopathy 6 | 15
Phaeochromocytoma 6 | 20
aldosterone-producing adenoma 6 | 664
non-small cell lung cancer 6 | 2,798
primitive neuroectodermal tumor 6 | 3,031
subependymal giant cell astrocytoma 6 | 2,287
Cardiomyopathies 5 | 90
Cerebrovascular disease 5 | 231
Hypertrophic Cardiomyopathy 5 | 56
Kidney disease 5 | 397
MELAS syndrome 5 | 17
Mitochondrial Encephalomyopathies 5 | 11
Mitochondrial complex II deficiency 5 | 5
Neurofibromatosis 5 | 37
Pneumonia 5 | 133
Rheumatoid Arthritis 5 | 1,171
Schizophrenia 5 | 503
group 4 medulloblastoma 5 | 1,875
pancreatic cancer 5 | 2,300
pituitary cancer 5 | 1,972
tuberculosis 5 | 1,563
Alzheimer's disease 4 | 644
Cardiomyopathy 4 | 110
Coronary artery disease 4 | 240
Degenerative polyarthritis 4 | 93
Gastrointestinal stromal tumor 4 | 61
Heart disease 4 | 279
Malaria 4 | 140
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome 4 | 5
Osteoporosis 4 | 259
Polycystic Ovary Syndrome 4 | 335
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,670
extra-adrenal pheochromocytoma 4 | 7
invasive ductal carcinoma 4 | 2,950
lung carcinoma 4 | 2,844
pilocytic astrocytoma 4 | 3,086
tuberculosis and treatment for 6 months 4 | 686
3-methylglutaconic aciduria 3 | 29
Arthritis 3 | 248
Disease Progression 3 | 125
Hypertension 3 | 293
Peripheral Neuropathy 3 | 303
Stomach Neoplasms 3 | 282
acute quadriplegic myopathy 3 | 1,157
pancreatic carcinoma 3 | 567

Tissue

Cardiovascular System 112 | 17,958
Endocrine System 112 | 18,512
Female tissues 112 | 18,647
Liver and Pancreas 112 | 18,136
Nervous System 112 | 18,561
Skin and soft tissues 112 | 18,115
Urinary Tract 112 | 18,444
Blood and immune system 111 | 17,995
Digestive Tract 111 | 18,473
Male tissues 111 | 17,969
Respiratory system 111 | 17,484

Target Family

Enzyme 87 | 4,146
Non-IDG 22 | 11,969
Transcription Factor 2 | 1,400
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

GO:0098803 114 | 114
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tetratricopeptide repeat protein 19, mitochondrial TTC19 Tbio Non-IDG -0.92140 9.50 28
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.58383 36.7 127
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 Tclin Enzyme -0.92007 7.73 98
WD repeat-containing protein 93 WDR93 Tdark Non-IDG 1.49 0.03 51
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.04600 11.8 165
Cytochrome b MT-CYB Tbio Non-IDG -3.75654 5676.0 122
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 Tclin Enzyme -0.17183 1.29 113
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 Tclin Enzyme -2.13957 109.9 147
Cytochrome c CYCS Tbio Non-IDG -3.74654 4771.4 630
Cytochrome c oxidase subunit 7B, mitochondrial COX7B Tbio Enzyme -0.60815 3.69 49