Development Level

Tbio 594 | 11,445
Tchem 96 | 1,598
Tdark 88 | 6,588
Tclin 72 | 613

Collection

Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 5 | 126
Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 61 | 979
preweaning lethality, incomple... 39 | 499
abnormal behavior 33 | 298
embryonic lethality prior to t... 20 | 278
increased lean body mass 20 | 172
decreased body weight 17 | 161
decreased total body fat amoun... 16 | 207
abnormal bone structure 14 | 187
abnormal embryo size 14 | 220
decreased grip strength 14 | 116
increased circulating sodium l... 14 | 71
increased circulating chloride... 13 | 41
hyperactivity 12 | 148
increased circulating alkaline... 12 | 122
increased fasted circulating g... 12 | 76
increased total body fat amoun... 12 | 134
decreased circulating choleste... 11 | 93
hypoactivity 11 | 132
impaired glucose tolerance 11 | 75
decreased bone mineral content 10 | 151
decreased circulating serum al... 10 | 82
decreased fasted circulating g... 10 | 65
decreased lean body mass 10 | 135
decreased vertical activity 10 | 208
increased bone mineral content 10 | 108
abnormal retina morphology 9 | 71
decreased circulating HDL chol... 9 | 68
decreased circulating alkaline... 9 | 46
decreased circulating glucose ... 9 | 126
decreased circulating triglyce... 9 | 79
embryonic growth retardation 9 | 106
embryonic lethality prior to o... 9 | 239
male infertility 9 | 123
short tibia 9 | 97
decreased circulating insulin ... 8 | 76
decreased circulating total pr... 8 | 49
increased or absent threshold ... 8 | 101
decreased circulating LDL chol... 7 | 38
improved glucose tolerance 7 | 79
increased mean corpuscular vol... 7 | 92
increased startle reflex 7 | 112
persistence of hyaloid vascula... 7 | 33
prolonged ST segment 7 | 36
tremors 7 | 39
abnormal behavioral response t... 6 | 66
abnormal eye morphology 6 | 68
abnormal sleep behavior 6 | 70
decreased leukocyte cell numbe... 6 | 73
edema 6 | 59
enlarged heart 6 | 210
increased blood urea nitrogen ... 6 | 48
increased mean corpuscular hem... 6 | 96
limb grasping 6 | 41
prenatal lethality prior to he... 6 | 87
prolonged QT interval 6 | 38
abnormal heart morphology 5 | 162
cardiovascular system phenotyp... 5 | 36
cataract 5 | 92
decreased bone mineral density 5 | 126
decreased caudal vertebrae num... 5 | 53
decreased circulating amylase ... 5 | 28
decreased circulating aspartat... 5 | 34
decreased hemoglobin content 5 | 68
decreased lymphocyte cell numb... 5 | 83
decreased neutrophil cell numb... 5 | 42
decreased prepulse inhibition 5 | 82
decreased startle reflex 5 | 75
increased circulating choleste... 5 | 66
small testis 5 | 58
abnormal embryo turning 4 | 31
abnormal gait 4 | 69
abnormal lens morphology 4 | 81
abnormal locomotor behavior 4 | 24
abnormal seminal vesicle morph... 4 | 114
abnormal spleen morphology 4 | 55
decreased circulating alanine ... 4 | 47
decreased mean corpuscular vol... 4 | 79
increased bone mineral density 4 | 72
increased circulating triglyce... 4 | 42
increased heart weight 4 | 62
increased lymphocyte cell numb... 4 | 32
increased prepulse inhibition 4 | 32
pallor 4 | 34
polycystic kidney 4 | 15
abnormal coat-hair pigmentatio... 3 | 64
abnormal retinal vasculature m... 3 | 27
convulsive seizures 3 | 13
corneal opacity 3 | 32
decreased body length 3 | 101
decreased circulating calcium ... 3 | 36
decreased circulating glycerol... 3 | 16
increased circulating HDL chol... 3 | 80
increased circulating amylase ... 3 | 25
increased circulating free fat... 3 | 20
increased circulating iron lev... 3 | 30
increased circulating phosphat... 3 | 26
increased circulating total pr... 3 | 28
increased red blood cell distr... 3 | 34
small thymus 3 | 16
thin ventricular wall 3 | 24

Disease

Carcinoma 642 | 11,493
ovarian cancer 380 | 8,520
osteosarcoma 379 | 7,950
medulloblastoma, large-cell 371 | 6,241
ependymoma 360 | 4,679
glioblastoma 360 | 5,792
atypical teratoid / rhabdoid tumor 330 | 5,112
psoriasis 324 | 6,694
adult high grade glioma 263 | 3,801
group 3 medulloblastoma 252 | 4,104
lung cancer 240 | 4,740
Astrocytoma, Pilocytic 225 | 3,081
oligodendroglioma 214 | 2,850
Kidney cancer 213 | 2,613
astrocytic glioma 194 | 2,597
Breast cancer 193 | 3,578
primitive neuroectodermal tumor 190 | 3,035
lung carcinoma 186 | 2,843
malignant mesothelioma 183 | 3,232
Cancer 169 | 2,499
Schizophrenia 164 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 159 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 149 | 2,989
Pick disease 146 | 1,894
invasive ductal carcinoma 146 | 2,951
lung adenocarcinoma 143 | 2,716
non-small cell lung cancer 143 | 2,890
Autosomal recessive predisposition 140 | 1,442
subependymal giant cell astrocytoma 140 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 138 | 3,291
Intellectual disability 137 | 1,016
pancreatic cancer 129 | 2,398
pituitary cancer 117 | 1,972
Bipolar Disorder 116 | 666
interstitial cystitis 116 | 2,312
Alzheimer's disease 110 | 658
Epilepsy 106 | 792
colon cancer 98 | 1,478
ulcerative colitis 98 | 1,819
Obesity 97 | 678
tuberculosis 94 | 2,010
diabetes mellitus 90 | 1,728
Depressive disorder 88 | 409
group 4 medulloblastoma 88 | 1,855
breast carcinoma 86 | 1,638
cystic fibrosis 85 | 1,696
Dull intelligence 84 | 645
Low intelligence 84 | 645
Mental Retardation 84 | 645
Mental deficiency 84 | 645
Poor school performance 84 | 645
ductal carcinoma in situ 84 | 1,745
Seizures 81 | 596
Parkinson's disease 76 | 392
nasopharyngeal carcinoma 76 | 1,058
Liver cancer 73 | 604
Mental Depression 73 | 333
adrenocortical carcinoma 73 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,962
chronic rhinosinusitis 68 | 512
Retinitis Pigmentosa 66 | 226
Cognitive delay 65 | 608
Global developmental delay 65 | 608
Mental and motor retardation 65 | 608
Alcoholic Intoxication, Chronic 63 | 289
Melanoma 63 | 711
pediatric high grade glioma 63 | 1,064
primary pancreatic ductal adenocarcinoma 60 | 1,109
Major Depressive Disorder 59 | 301
astrocytoma 59 | 1,146
Autistic Disorder 58 | 364
Nystagmus 58 | 317
cutaneous lupus erythematosus 58 | 1,057
Hypertension 56 | 396
Kidney disease 55 | 430
spina bifida 55 | 1,074
Cataract 54 | 297
Polydactyly 54 | 107
Toxic encephalopathy 54 | 141
acute quadriplegic myopathy 54 | 1,158
Muscle hypotonia 53 | 571
Skin cancer 53 | 469
Rheumatoid arthritis 52 | 1,191
Unipolar Depression 52 | 250
Neurodegenerative disease 51 | 414
Down syndrome 49 | 499
Amyotrophic lateral sclerosis 48 | 451
Lens Opacities 48 | 231
Short stature 48 | 531
Congenital hypoplasia of penis 46 | 176
Hypertensive disease 46 | 292
juvenile dermatomyositis 46 | 1,187
Cerebrovascular disease 45 | 238
Hypogonadism 44 | 173
Mood Disorders 44 | 184
Neuropathy 44 | 261
Cerebellar Ataxia 41 | 304
Ciliopathy 41 | 71
Electroretinogram abnormal 41 | 95
Nephronophthisis 41 | 80

Tissue

Endocrine System 827 | 18,159
Skin and soft tissues 792 | 17,230
Female tissues 790 | 17,400
Digestive Tract 789 | 17,369
Nervous System 786 | 16,725
Male tissues 784 | 17,142
Liver and Pancreas 768 | 16,750
Urinary Tract 767 | 16,678
Blood and immune system 761 | 16,909
Respiratory system 751 | 16,393
Cardiovascular System 671 | 15,192

Target Family

Non-IDG 550 | 12,091
Enzyme 125 | 4,145
Kinase 49 | 634
Ion Channel 40 | 344
GPCR 37 | 408
Transporter 36 | 473
Transcription Factor 8 | 1,400
Epigenetic 4 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Cell projection part 850 | 850
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative segment polarity protein dishevelled homolog DVL1P1 DVL1P1 Tdark Non-IDG -2.11561 188.4 0
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.40552 26.1 61
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
G-protein coupled receptor 157 GPR157 Tdark GPCR -0.04139 1.14 111
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127