Development Level

Tbio 1,733 | 11,178
Tchem 569 | 1,885
Tclin 226 | 612
Tdark 132 | 6,569

Collection

Kinase: IDG Consortium (Target... 9 | 125
GPCR: IDG Consortium (Complete... 7 | 25
Ion Channel: IDG Consortium (T... 7 | 99
GPCR: IDG Consortium (Targets) 5 | 126
Kinase: IDG Consortium (Comple... 4 | 37

IMPC Phenotype

preweaning lethality, complete... 285 | 979
preweaning lethality, incomple... 155 | 499
enlarged heart 126 | 210
embryonic lethality prior to t... 104 | 278
abnormal heart morphology 80 | 162
decreased vertical activity 80 | 208
abnormal embryo size 79 | 220
abnormal behavior 78 | 298
abnormal bone structure 70 | 187
decreased total body fat amoun... 68 | 207
embryonic lethality prior to o... 58 | 239
decreased body weight 53 | 161
increased lean body mass 53 | 172
decreased bone mineral content 49 | 151
decreased lean body mass 47 | 135
abnormal seminal vesicle morph... 45 | 114
increased total body fat amoun... 42 | 134
hypoactivity 40 | 132
increased heart weight 40 | 62
increased circulating alkaline... 39 | 122
increased startle reflex 38 | 112
decreased grip strength 35 | 116
decreased mean corpuscular vol... 35 | 79
hyperactivity 35 | 148
decreased circulating glucose ... 34 | 126
embryonic growth retardation 34 | 106
decreased body length 33 | 101
decreased bone mineral density 31 | 126
decreased circulating choleste... 31 | 93
increased bone mineral content 31 | 108
abnormal eye morphology 30 | 68
cardiovascular system phenotyp... 30 | 36
decreased circulating serum al... 30 | 82
abnormal retina morphology 29 | 71
prenatal lethality prior to he... 29 | 87
short tibia 29 | 97
impaired glucose tolerance 28 | 75
cataract 26 | 92
abnormal gait 25 | 69
decreased circulating HDL chol... 25 | 68
decreased circulating triglyce... 25 | 79
decreased hemoglobin content 25 | 68
abnormal neural tube closure 24 | 46
decreased prepulse inhibition 24 | 82
edema 24 | 59
improved glucose tolerance 24 | 79
increased mean corpuscular vol... 24 | 92
abnormal lens morphology 23 | 81
abnormal sleep behavior 23 | 70
decreased fasted circulating g... 23 | 65
decreased lymphocyte cell numb... 23 | 83
male infertility 23 | 123
increased circulating HDL chol... 22 | 80
increased or absent threshold ... 22 | 101
decreased circulating insulin ... 21 | 76
decreased startle reflex 21 | 75
increased circulating sodium l... 21 | 71
increased fasted circulating g... 21 | 76
pale yolk sac 21 | 25
small superior vagus ganglion 21 | 74
abnormal retinal blood vessel ... 20 | 26
increased circulating choleste... 20 | 66
limb grasping 19 | 41
abnormal cranium morphology 18 | 36
decreased circulating alkaline... 18 | 46
decreased circulating total pr... 18 | 49
increased blood urea nitrogen ... 18 | 48
increased circulating triglyce... 18 | 42
pallor 18 | 34
abnormal pericardium morpholog... 17 | 26
abnormal retinal vasculature m... 17 | 27
abnormal testis morphology 17 | 43
corneal opacity 17 | 32
decreased blood urea nitrogen ... 17 | 51
decreased erythrocyte cell num... 17 | 62
enlarged spleen 17 | 41
hemorrhage 17 | 23
hydrometra 17 | 53
increased bone mineral density 17 | 72
increased circulating chloride... 17 | 41
increased mean corpuscular hem... 17 | 96
increased neutrophil cell numb... 17 | 46
tremors 17 | 39
abnormal behavioral response t... 16 | 66
abnormal kidney morphology 16 | 65
abnormal skin morphology 16 | 50
decreased mean corpuscular hem... 16 | 50
abnormal coat-hair pigmentatio... 15 | 64
decreased circulating calcium ... 15 | 36
decreased heart weight 15 | 27
decreased hematocrit 15 | 46
increased circulating calcium ... 15 | 34
increased circulating creatini... 15 | 38
prolonged QT interval 15 | 38
prolonged ST segment 15 | 36
small testis 15 | 58
abnormal bone mineralization 14 | 38
abnormal epididymis morphology 14 | 42
abnormal spleen morphology 14 | 55
increased prepulse inhibition 14 | 32

Disease

Carcinoma 1,816 | 11,192
ovarian cancer 1,453 | 8,297
osteosarcoma 1,277 | 7,766
psoriasis 1,165 | 6,514
glioblastoma 1,054 | 5,635
medulloblastoma, large-cell 1,039 | 6,086
lung cancer 974 | 4,607
atypical teratoid / rhabdoid tumor 870 | 4,971
Cancer 836 | 2,388
ependymoma 829 | 4,559
Breast cancer 759 | 3,469
malignant mesothelioma 676 | 3,135
group 3 medulloblastoma 650 | 4,002
intraductal papillary-mucinous neoplasm (IPMN) 643 | 3,204
invasive ductal carcinoma 632 | 2,867
adult high grade glioma 631 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 621 | 2,872
non-small cell lung cancer 605 | 2,799
intraductal papillary-mucinous carcinoma (IPMC) 601 | 2,902
lung adenocarcinoma 596 | 2,627
lung carcinoma 593 | 2,755
Astrocytoma, Pilocytic 573 | 3,006
Kidney cancer 561 | 2,548
pancreatic cancer 560 | 2,322
primitive neuroectodermal tumor 512 | 2,957
oligodendroglioma 495 | 2,768
interstitial cystitis 470 | 2,237
Autosomal recessive predisposition 443 | 1,407
astrocytic glioma 425 | 2,530
subependymal giant cell astrocytoma 403 | 2,230
tuberculosis 402 | 1,963
pituitary cancer 398 | 1,915
ulcerative colitis 393 | 1,765
diabetes mellitus 391 | 1,683
ductal carcinoma in situ 391 | 1,686
pancreatic ductal adenocarcinoma liver metastasis 386 | 1,911
breast carcinoma 384 | 1,589
colon cancer 375 | 1,428
cystic fibrosis 374 | 1,629
group 4 medulloblastoma 338 | 1,806
Schizophrenia 334 | 1,136
Pick disease 320 | 1,856
adrenocortical carcinoma 318 | 1,385
Intellectual disability 284 | 998
juvenile dermatomyositis 277 | 1,147
acute quadriplegic myopathy 269 | 1,133
Rheumatoid arthritis 265 | 1,156
primary pancreatic ductal adenocarcinoma 264 | 1,071
astrocytoma 256 | 1,113
Obesity 234 | 655
spina bifida 228 | 1,053
Epilepsy 226 | 775
dermatomyositis 223 | 941
Hypertension 220 | 372
Multiple myeloma 217 | 1,296
Dull intelligence 211 | 634
Low intelligence 211 | 634
Mental Retardation 211 | 634
Mental deficiency 211 | 634
Poor school performance 211 | 634
pediatric high grade glioma 210 | 1,035
Bipolar Disorder 206 | 646
Seizures 204 | 584
cutaneous lupus erythematosus 203 | 1,016
gastric carcinoma 201 | 781
Liver Cirrhosis, Experimental 198 | 733
Short stature 197 | 514
Muscle hypotonia 189 | 562
Breast Neoplasms 188 | 423
Kidney disease 186 | 411
Atopic dermatitis 184 | 915
Hypertensive disease 184 | 278
Prostatic Neoplasms 183 | 472
Alzheimer's disease 180 | 640
Mammary Neoplasms 180 | 403
Cognitive delay 179 | 596
Global developmental delay 179 | 596
Mental and motor retardation 179 | 596
Melanoma 175 | 689
nasopharyngeal carcinoma 174 | 1,024
Depressive disorder 166 | 401
Liver cancer 166 | 589
autosomal dominant Emery-Dreifuss muscular dystrophy 164 | 492
active ulcerative colitis 163 | 736
active Crohn's disease 162 | 882
Duchenne muscular dystrophy 159 | 587
Heart disease 157 | 288
aldosterone-producing adenoma 153 | 646
esophageal adenocarcinoma 152 | 696
acute myeloid leukemia 145 | 760
Atherosclerosis 143 | 276
medulloblastoma 141 | 702
non primary Sjogren syndrome sicca 137 | 861
Coronary artery disease 136 | 253
Down syndrome 136 | 480
Vascular disease 134 | 294
primary Sjogren syndrome 134 | 710
Waldenstrons macroglobulinemia 133 | 742
Endometriosis 132 | 521
fibroadenoma 132 | 538

Tissue

Endocrine System 2,621 | 18,159
Digestive Tract 2,587 | 17,369
Female tissues 2,574 | 17,400
Skin and soft tissues 2,572 | 17,230
Male tissues 2,558 | 17,142
Urinary Tract 2,534 | 16,678
Liver and Pancreas 2,524 | 16,750
Blood and immune system 2,521 | 16,909
Nervous System 2,511 | 16,725
Respiratory system 2,486 | 16,393
Cardiovascular System 2,384 | 15,192

Target Family

Non-IDG 1,310 | 12,091
Enzyme 552 | 4,145
Transcription Factor 280 | 1,400
Kinase 179 | 634
GPCR 105 | 408
Ion Channel 74 | 344
Transporter 65 | 473
Epigenetic 51 | 242
Nuclear Receptor 30 | 48
TF/Epigenetic 13 | 38
oGPCR 1 | 421

MGI Phenotype

cardiovascular system phenotyp... 2,660 | 2,660
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability