Development Level

Tbio 23 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602

IMPC Phenotype

increased circulating sodium l... 2 | 71
cardiovascular system phenotyp... 1 | 35
decreased heart rate variabili... 1 | 11
decreased prepulse inhibition 1 | 52
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
shortened RR interval 1 | 19
thrombocytopenia 1 | 46

Disease

ovarian cancer 15 | 8,491
lung cancer 13 | 4,473
lung carcinoma 13 | 2,844
non-small cell lung cancer 12 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Complement deficiency 10 | 15
malignant mesothelioma 10 | 3,163
Age related macular degeneration 9 | 84
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung adenocarcinoma 9 | 2,714
psoriasis 9 | 6,685
Cancer 8 | 2,346
glioblastoma 8 | 5,572
invasive ductal carcinoma 8 | 2,950
pilocytic astrocytoma 8 | 3,086
ulcerative colitis 8 | 2,087
Anemia 7 | 252
Kidney disease 7 | 397
Vascular disease 7 | 281
hemolytic-uremic syndrome 7 | 28
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
osteosarcoma 7 | 7,933
Atypical Hemolytic Uremic Syndrome 6 | 9
Immunologic Deficiency Syndromes 6 | 16
Rheumatoid Arthritis 6 | 1,170
dermatomyositis 6 | 966
mucosa-associated lymphoid tissue lymphoma 6 | 480
pancreatic cancer 6 | 2,300
subependymal giant cell astrocytoma 6 | 2,287
Carcinoma 5 | 2,147
IGA Glomerulonephritis 5 | 454
Macular degeneration 5 | 44
Meningitis 5 | 46
adrenocortical carcinoma 5 | 1,427
Breast cancer 4 | 3,098
Thrombocytopenia 4 | 105
Type 1 diabetes mellitus 4 | 104
active Crohn's disease 4 | 918
astrocytoma 4 | 1,493
atypical teratoid / rhabdoid tumor 4 | 4,369
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
gastric carcinoma 4 | 832
group 4 medulloblastoma 4 | 1,875
medulloblastoma, large-cell 4 | 6,234
oligodendroglioma 4 | 2,849
posterior fossa group A ependymoma 4 | 1,511
systemic lupus erythematosus 4 | 172
tuberculosis 4 | 1,563
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Complement component 3 deficiency 3 | 8
Congenital afibrinogenemia 3 | 9
Down syndrome 3 | 548
Duchenne muscular dystrophy 3 | 602
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 3 | 6
Macular Degeneration, Age-Related, 1 3 | 9
Multiple Sclerosis 3 | 498
Protein S deficiency 3 | 5
Thrombotic thrombocytopenic purpura 3 | 14
cystic fibrosis 3 | 1,670
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 292
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 788
Barrett's esophagus 2 | 185
Becker muscular dystrophy 2 | 187
Congenital adrenal hyperplasia 2 | 74
Hypermobility syndrome 2 | 17
Juvenile arthritis 2 | 124
Lupus Erythematosus, Systemic 2 | 73
Malaria 2 | 140
Multiple myeloma 2 | 1,327
Myasthenia Gravis 2 | 26
Pick disease 2 | 1,893
Proteinuria 2 | 63
Relapsing fever 2 | 16
Skin disease 2 | 65
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
axial spondyloarthropathy 2 | 28
chronic lymphosyte leukemia 2 | 232
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
hepatocellular carcinoma 2 | 550
juvenile dermatomyositis 2 | 1,189
limb girdle muscular dystrophy 2A 2 | 156
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
pediatric high grade glioma 2 | 2,712
periodontitis 2 | 269
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 26 | 17,994
Cardiovascular System 26 | 17,957
Digestive Tract 26 | 18,472
Endocrine System 26 | 18,511
Female tissues 26 | 18,646
Liver and Pancreas 26 | 18,135
Male tissues 26 | 17,968
Nervous System 26 | 18,560
Respiratory system 26 | 17,483
Skin and soft tissues 26 | 18,114
Urinary Tract 26 | 18,443

Target Family

Non-IDG 22 | 11,969
GPCR 3 | 408
Transcription Factor 1 | 1,400

Reactome Pathway

Regulation of Complement casca... 26 | 26
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement factor B CFB Tbio Non-IDG -2.83107 695.7 426
Complement C4-B C4B Tbio Non-IDG -2.98393 993.5 152
Complement C4-A C4B Tbio Non-IDG -3.02793 1088.3 292
CD59 glycoprotein CD59 Tbio Non-IDG -3.25220 1768.6 739
Complement component C6 C6 Tbio Non-IDG -1.55226 35.0 124
Complement factor H CFH Tbio Non-IDG -3.13081 1330.3 512
Vitamin K-dependent protein S PROS1 Tbio Non-IDG -3.29749 1853.9 227
Complement component C9 C9 Tbio Non-IDG -1.87453 71.0 229
Complement component C7 C7 Tbio Non-IDG -1.39423 24.2 122
C5a anaphylatoxin chemotactic receptor 2 C5AR2 Tbio GPCR -1.79926 63.3 207