Development Level

Tdark 71 | 6,593
Tbio 39 | 11,651
Tchem 6 | 1,388
Tclin 5 | 612

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
increased circulating sodium l... 2 | 71
preweaning lethality, incomple... 2 | 499
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hypoactivity 1 | 132
increased aggression 1 | 4
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
polycystic kidney 1 | 15
shortened RR interval 1 | 17
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 34 | 11,493
lung cancer 26 | 4,740
ovarian cancer 25 | 8,520
non-small cell lung cancer 24 | 2,890
psoriasis 24 | 6,694
interstitial cystitis 23 | 2,312
lung adenocarcinoma 23 | 2,716
lung carcinoma 22 | 2,843
Autosomal recessive predisposition 21 | 1,442
ulcerative colitis 21 | 1,819
osteosarcoma 20 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
periodontitis 16 | 293
tuberculosis 16 | 2,010
glioblastoma 15 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
Age related macular degeneration 14 | 72
Cancer 14 | 2,499
Astrocytoma, Pilocytic 13 | 3,081
Kidney disease 13 | 430
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
pancreatic cancer 12 | 2,398
subependymal giant cell astrocytoma 12 | 2,287
Complement deficiency 11 | 14
Hemolytic-Uremic Syndrome 11 | 30
Anemia 10 | 365
Immunologic Deficiency Syndromes 10 | 113
adrenocortical carcinoma 10 | 1,428
dermatomyositis 10 | 966
medulloblastoma, large-cell 10 | 6,241
primary Sjogren syndrome 10 | 735
Duchenne muscular dystrophy 9 | 601
Melanoma 9 | 711
Meningitis 9 | 67
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
Systemic lupus erythematosus 9 | 194
chronic lymphosyte leukemia 9 | 204
colon cancer 9 | 1,478
ependymoma 9 | 4,679
juvenile dermatomyositis 9 | 1,187
mucosa-associated lymphoid tissue lymphoma 9 | 484
Kidney cancer 8 | 2,613
Skin cancer 8 | 469
Vascular disease 8 | 319
acute quadriplegic myopathy 8 | 1,158
cystic fibrosis 8 | 1,696
limb girdle muscular dystrophy 2A 8 | 213
Atypical Hemolytic Uremic Syndrome 7 | 9
Breast cancer 7 | 3,578
Lupus Erythematosus, Systemic 7 | 67
atypical teratoid / rhabdoid tumor 7 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
diabetes mellitus 7 | 1,728
nasopharyngeal carcinoma 7 | 1,058
pituitary cancer 7 | 1,972
Arthritis 6 | 290
Atopic dermatitis 6 | 952
Autoimmune Diseases 6 | 67
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 6 | 7
Increased susceptibility to bacterial infections 6 | 42
Macular degeneration 6 | 65
Prone to bacterial infection 6 | 42
Purpura 6 | 43
Recurrent bacterial infection 6 | 42
Schizophrenia 6 | 1,160
Thrombocytopenia 6 | 197
adult high grade glioma 6 | 3,801
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
esophageal adenocarcinoma 6 | 737
group 3 medulloblastoma 6 | 4,104
primary pancreatic ductal adenocarcinoma 6 | 1,109
Becker muscular dystrophy 5 | 191
Liver Cirrhosis, Experimental 5 | 769
Lymphoma 5 | 81
Multiple Sclerosis 5 | 540
Skin disease 5 | 66
active ulcerative colitis 5 | 764
chronic kidney disease 5 | 90
cystic fibrosis and chronic rhinosinusitis 5 | 214
gastric carcinoma 5 | 807
non-small cell lung carcinoma 5 | 317
oligodendroglioma 5 | 2,850
sonic hedgehog group medulloblastoma 5 | 467
Alzheimer's disease 4 | 658
Atherosclerosis 4 | 291
Diarrhea 4 | 253
Disseminated intravascular coagulation 4 | 38
Down syndrome 4 | 499
Glomerulonephritis, IGA 4 | 34
IGA Glomerulonephritis 4 | 50
Liver Cirrhosis 4 | 181
active Crohn's disease 4 | 922
astrocytic glioma 4 | 2,597
hepatocellular carcinoma 4 | 547

Tissue

Liver and Pancreas 44 | 16,750
Urinary Tract 44 | 16,678
Endocrine System 42 | 18,159
Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Skin and soft tissues 38 | 17,230
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Nervous System 32 | 16,725
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 111 | 12,091
Enzyme 6 | 4,145
GPCR 3 | 408
Transcription Factor 1 | 1,400

Reactome Pathway

Regulation of Complement casca... 121 | 121
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement factor H-related protein 2 CFHR2 Tbio Non-IDG -1.01743 9.09 82
CD59 glycoprotein CD59 Tbio Non-IDG -3.26937 1829.9 1039
Complement component C6 C6 Tbio Non-IDG -1.55226 36.1 153
Complement C1r subcomponent C1R Tclin Non-IDG -2.52739 315.0 221
Complement factor B CFB Tbio Non-IDG -2.85144 694.6 495
Complement C1s subcomponent C1S Tchem Non-IDG -3.00029 964.1 305
Vitamin K-dependent protein S PROS1 Tbio Non-IDG -3.36389 2143.9 268
Clusterin CLU Tbio Non-IDG -3.28651 2016.4 826
Complement factor H CFH Tbio Non-IDG -3.15872 1420.9 593
Complement component C7 C7 Tbio Non-IDG -1.39617 24.3 164