Development Level

Tbio 15 | 11,445
Tchem 6 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
decreased caudal vertebrae num... 1 | 53
head bobbing 1 | 5
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Astrocytoma, Pilocytic 18 | 3,081
ependymoma 18 | 4,679
glioblastoma 18 | 5,792
adult high grade glioma 17 | 3,801
atypical teratoid / rhabdoid tumor 17 | 5,112
medulloblastoma, large-cell 17 | 6,241
Carcinoma 16 | 11,493
oligodendroglioma 16 | 2,850
primitive neuroectodermal tumor 15 | 3,035
Pick disease 14 | 1,894
Schizophrenia 14 | 1,160
astrocytic glioma 14 | 2,597
group 3 medulloblastoma 14 | 4,104
subependymal giant cell astrocytoma 13 | 2,287
ovarian cancer 10 | 8,520
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Bipolar Disorder 8 | 666
lung carcinoma 8 | 2,843
malignant mesothelioma 8 | 3,232
Epilepsy 7 | 792
Kidney cancer 7 | 2,613
Parkinson's disease 6 | 392
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Depressive disorder 4 | 409
Mental Depression 4 | 333
Seizures 4 | 596
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
Amyotrophic lateral sclerosis 3 | 451
Autistic Disorder 3 | 364
Botulism 3 | 24
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Dicarboxylic aminoaciduria 3 | 4
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Rheumatoid arthritis 3 | 1,191
Toxic encephalopathy 3 | 141
Wernicke encephalopathy 3 | 12
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
Anhedonia 2 | 27
Atopic dermatitis 2 | 952
Attention deficit hyperactivity disorder 2 | 278
Blepharoptosis 2 | 231
Cancer 2 | 2,499
Cataract 7 2 | 32
Cerebellar Ataxia 2 | 304
Down syndrome 2 | 499
Gaucher disease type 1 2 | 180
Heart disease 2 | 306
Hypomyelinating leukodystrophy 6 2 | 26
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Major Depressive Disorder 2 | 301
Multiple myeloma 2 | 1,332
Nager acrofacial dysostosis 2 | 21
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Neurodevelopmental Disorders 2 | 70
Oppositional defiant disorder 2 | 17
Psychotic Disorders 2 | 151
Reduced fetal movement 2 | 51
Severe mental retardation (I.Q. 20-34) 2 | 99
Tetanus 2 | 68
Unipolar Depression 2 | 250
Vascular disease 2 | 319
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
Abnormal color vision 1 | 31
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Episodic ataxia 1 | 22
Neonatal onset 1 | 21
Neurofibromatosis 1 | 40
Problems speaking 1 | 37
Tonic - clonic seizures 1 | 44
cone-rod dystrophy 1 | 59

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 13 | 12,091
Transporter 7 | 473
Enzyme 3 | 4,145

Reactome Pathway

Glutamate Neurotransmitter Rel... 23 | 23
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Liprin-alpha-3 PPFIA3 Tdark Non-IDG -1.44046 26.8 42
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Liprin-alpha-4 PPFIA4 Tdark Non-IDG 0.13 1.07 31
Liprin-alpha-2 PPFIA2 Tbio Non-IDG -0.44401 2.81 63
Synaptotagmin-1 SYT1 Tbio Non-IDG -2.66042 455.0 616
Synaptosomal-associated protein 25 SNAP25 Tbio Non-IDG -2.61491 385.0 821
Protein unc-13 homolog B UNC13B Tbio Non-IDG -2.08635 111.4 161
Complexin-1 CPLX1 Tbio Non-IDG -1.92730 82.0 106
Vesicular glutamate transporter 1 SLC17A7 Tbio Transporter -2.57149 347.9 159
Excitatory amino acid transporter 3 SLC1A1 Tchem Transporter -2.59660 395.6 251