Development Level

Tbio 37 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

decreased total body fat amoun... 3 | 207
abnormal femur morphology 2 | 14
impaired glucose tolerance 2 | 75
abnormal ear morphology 1 | 9
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
dilated heart left ventricle 1 | 11
enlarged lymph nodes 1 | 37
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97

Disease

Carcinoma 42 | 11,493
ovarian cancer 31 | 8,520
Astrocytoma, Pilocytic 27 | 3,081
Kidney cancer 27 | 2,613
glioblastoma 24 | 5,792
lung cancer 24 | 4,740
Breast cancer 23 | 3,578
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 22 | 4,679
psoriasis 21 | 6,694
medulloblastoma, large-cell 19 | 6,241
pancreatic cancer 19 | 2,398
pituitary cancer 19 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
lung adenocarcinoma 17 | 2,716
osteosarcoma 17 | 7,950
gastric carcinoma 16 | 807
Duchenne muscular dystrophy 15 | 601
Skin cancer 15 | 469
adult high grade glioma 15 | 3,801
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
primitive neuroectodermal tumor 15 | 3,035
Autosomal recessive predisposition 14 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
nasopharyngeal carcinoma 14 | 1,058
non-small cell lung cancer 14 | 2,890
ulcerative colitis 14 | 1,819
Melanoma 13 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
breast carcinoma 13 | 1,638
Degenerative polyarthritis 12 | 115
Myopia 12 | 176
Short stature 12 | 531
cystic fibrosis 12 | 1,696
urothelial carcinoma 12 | 318
Becker muscular dystrophy 11 | 191
interstitial lung disease 11 | 298
Hypoplastic mandible condyle 10 | 275
Joint hyperflexibility 10 | 78
Liver Cirrhosis, Experimental 10 | 769
Liver cancer 10 | 604
Mandibular hypoplasia 10 | 275
Micrognathism 10 | 275
group 3 medulloblastoma 10 | 4,104
juvenile dermatomyositis 10 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Abortion, Spontaneous 9 | 109
Acquired scoliosis 9 | 281
Cataract 9 | 297
Curvature of spine 9 | 282
Osteoarthritis 9 | 184
Pick disease 9 | 1,894
Spontaneous abortion 9 | 113
ductal carcinoma in situ 9 | 1,745
limb girdle muscular dystrophy 2A 9 | 213
Hyperkyphosis 8 | 111
Hypotrophic malar bone 8 | 129
Kyphosis deformity of spine 8 | 114
Lens Opacities 8 | 231
Malar flattening 8 | 129
Platyspondyly 8 | 56
Respiratory Insufficiency 8 | 132
Respiratory function loss 8 | 121
Sensorineural Hearing Loss (disorder) 8 | 284
adrenocortical carcinoma 8 | 1,428
oligodendroglioma 8 | 2,850
primary pancreatic ductal adenocarcinoma 8 | 1,109
pterygium 8 | 76
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Contracture 7 | 96
Contracture of joint 7 | 93
Ehlers-Danlos syndrome 7 | 43
Flat face 7 | 52
Flexion contracture 7 | 93
Flexion contractures of joints 7 | 93
colon cancer 7 | 1,478
esophageal adenocarcinoma 7 | 737
group 4 medulloblastoma 7 | 1,855
Arthralgia 6 | 90
Congenital clubfoot 6 | 109
Congenital deafness 6 | 185
Deafness 6 | 198
Hearing Loss, Partial 6 | 185
Hernia, Inguinal 6 | 89
Kidney disease 6 | 430
Micromelia 6 | 58
Pectus excavatum 6 | 100
Progressive disorder 6 | 142
Thin skin 6 | 47
Uranostaphyloschisis 6 | 167
active Crohn's disease 6 | 922
fibroadenoma 6 | 559
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
hearing impairment 6 | 199
lung carcinoma 6 | 2,843
pediatric high grade glioma 6 | 1,064

Tissue

Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Male tissues 43 | 17,142
Blood and immune system 42 | 16,909
Digestive Tract 42 | 17,369
Skin and soft tissues 42 | 17,230
Liver and Pancreas 41 | 16,750
Nervous System 41 | 16,725
Urinary Tract 40 | 16,678
Cardiovascular System 38 | 15,192
Respiratory system 38 | 16,393

Target Family

Non-IDG 43 | 12,091

Reactome Pathway

Collagen chain trimerization 43 | 43
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Collagen alpha-1(XXVIII) chain COL28A1 Tdark Non-IDG 0.78 0.10 6
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Collagen alpha-1(XIX) chain COL19A1 Tbio Non-IDG -0.75672 6.18 137
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Collagen alpha-2(XI) chain COL11A2 Tbio Non-IDG -1.89476 73.6 143
Collagen alpha-1(XXII) chain COL22A1 Tdark Non-IDG -0.59703 4.38 24
Collagen alpha-3(V) chain COL5A3 Tbio Non-IDG -0.80962 6.18 73
Collagen alpha-1(XIII) chain COL13A1 Tbio Non-IDG -1.17587 14.7 63