Development Level

Tbio 19 | 11,445
Tclin 12 | 613
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 4 | 239
preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal retinal vasculature m... 1 | 27
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased mean platelet volume 1 | 45
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 23 | 11,493
ovarian cancer 23 | 8,520
medulloblastoma, large-cell 22 | 6,241
lung cancer 20 | 4,740
psoriasis 17 | 6,694
osteosarcoma 16 | 7,950
Breast cancer 15 | 3,578
ependymoma 15 | 4,679
glioblastoma 15 | 5,792
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
group 3 medulloblastoma 11 | 4,104
non-small cell lung cancer 11 | 2,890
Autosomal recessive predisposition 10 | 1,442
oligodendroglioma 10 | 2,850
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
Cancer 9 | 2,499
Pick disease 9 | 1,894
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
lung adenocarcinoma 9 | 2,716
tuberculosis 9 | 2,010
Astrocytoma, Pilocytic 8 | 3,081
colon cancer 8 | 1,478
interstitial cystitis 8 | 2,312
Kidney cancer 7 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
nasopharyngeal carcinoma 7 | 1,058
Dull intelligence 6 | 645
Intellectual disability 6 | 1,016
Lesch-Nyhan syndrome 6 | 12
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Poor school performance 6 | 645
Purine nucleoside phosphorylase deficiency 6 | 11
group 4 medulloblastoma 6 | 1,855
malignant mesothelioma 6 | 3,232
ulcerative colitis 6 | 1,819
Atopic dermatitis 5 | 952
Epilepsy 5 | 792
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
ductal carcinoma in situ 5 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary pancreatic ductal adenocarcinoma 5 | 1,109
Anteverted nostril 4 | 191
Autistic Disorder 4 | 364
Mental Depression 4 | 333
Nystagmus 4 | 317
Optic Atrophy 4 | 242
Seizures 4 | 596
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma of lung 3 | 142
Asthma 3 | 385
Atrial Fibrillation 3 | 124
Bipolar Disorder 3 | 666
Brachycephaly 3 | 88
Breast Neoplasms 3 | 445
Broad cranium shape 3 | 88
Chronic heart failure 3 | 46
Disease Models, Animal 3 | 155
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Gout 3 | 106
Hyperreflexia 3 | 209
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Motor delay 3 | 147
Nephrolithiasis 3 | 56
No development of motor milestones 3 | 147
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Splenomegaly 3 | 190
Thrombocytopenia 3 | 197
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
Wide skull shape 3 | 88
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
inflammatory breast cancer 3 | 286
non primary Sjogren syndrome sicca 3 | 891
primary Sjogren syndrome 3 | 735

Tissue

Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 33 | 15,192
Nervous System 33 | 16,725

Target Family

Enzyme 28 | 4,145
Kinase 5 | 634
Non-IDG 4 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Xanthine dehydrogenase/oxidase XDH Tclin Enzyme -2.69810 506.6 179
Multifunctional protein ADE2 PAICS Tbio Non-IDG -2.19877 143.7 209
Ectonucleoside triphosphate diphosphohydrolase 5 ENTPD5 Tbio Enzyme -1.81869 64.1 186
Trifunctional purine biosynthetic protein adenosine-3 GART Tclin Non-IDG -2.26480 181.2 139
Ribose-phosphate pyrophosphokinase 3 PRPS1L1 Tdark Kinase -1.26374 18.3 0
AMP deaminase 1 AMPD1 Tchem Enzyme -2.35602 227.5 148
Purine nucleoside phosphorylase PNP Tclin Enzyme -2.75207 531.4 165
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A Tclin Enzyme -2.41274 268.1 140
Adenylosuccinate lyase ADSL Tbio Enzyme -3.32293 2023.8 144
ADP-sugar pyrophosphatase NUDT5 Tbio Enzyme -1.49012 32.8 61