Development Level

Tbio 13 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
decreased hemoglobin content 1 | 68
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased fasted circulating g... 1 | 76
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
Autosomal recessive predisposition 7 | 1,442
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
group 3 medulloblastoma 6 | 4,104
tuberculosis 6 | 2,010
Muscle hypotonia 5 | 571
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
subependymal giant cell astrocytoma 5 | 2,287
Byzanthine arch palate 4 | 194
Intellectual disability 4 | 1,016
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
medulloblastoma, large-cell 4 | 6,241
Cerebellar Ataxia 3 | 304
Coarse facial features 3 | 108
Cognitive delay 3 | 608
Congenital Epicanthus 3 | 177
Dull intelligence 3 | 645
Dysarthria 3 | 192
Epilepsy 3 | 792
Global developmental delay 3 | 608
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Seizures 3 | 596
Splenomegaly 3 | 190
Thickened facial skin with coarse facial features 3 | 108
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
Abnormality of metabolism/homeostasis 2 | 134
Acquired scoliosis 2 | 281
Adenocarcinoma of lung 2 | 142
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Curvature of spine 2 | 282
Disease Models, Animal 2 | 155
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Foot Deformities 2 | 30
Gaucher's disease 2 | 26
Hepatomegaly 2 | 285
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
Low posterior hairline 2 | 52
Metaphyseal irregularity 2 | 23
Mildly increased creatine kinase 2 | 20
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Nystagmus 2 | 317
Schizophrenia 2 | 1,160
Sialic Acid Storage Disease 2 | 2
Sialuria 2 | 9
Synophrys 2 | 40
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
Decreased muscle mass 1 | 28
EMG positive sharp waves 1 | 2
EMG: myotonic discharges 1 | 2
Hand deformities 1 | 32
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Irregular epiphyses 1 | 10
Irregular vertebral endplates 1 | 16
Limited wrist extension 1 | 2
NONAKA MYOPATHY 1 | 2
Posterior scalloping of vertebral bodies 1 | 3
Reflex, Ankle, Absent 1 | 8
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Sleep Apnea Syndromes 1 | 13
Small epiphyses 1 | 9
Splayed metaphyses 1 | 19
Spondyloepimetaphyseal disorder 1 | 9
Tibialis muscle weakness 1 | 2
Weakness of hip flexors 1 | 2

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Enzyme 14 | 4,145
Kinase 2 | 634
Transporter 1 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 17 | 17
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-acetylneuraminate lyase NPL Tbio Enzyme -3.10700 1259.2 86
N-acetyl-D-glucosamine kinase NAGK Tbio Kinase -1.63894 41.9 210
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
Beta-hexosaminidase subunit alpha HEXA Tchem Enzyme -2.83300 675.5 327
Glucosamine-6-phosphate isomerase 1 GNPDA1 Tbio Enzyme -1.94812 86.5 191
Hexokinase-1 HK1 Tchem Kinase -2.58967 375.7 571
Chitotriosidase-1 CHIT1 Tbio Enzyme -2.58852 382.5 153