Development Level

Tbio 55 | 11,445
Tchem 10 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
increased circulating triglyce... 3 | 42
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
decreased circulating bilirubi... 2 | 19
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased heart weight 2 | 62
persistence of hyaloid vascula... 2 | 33
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal tooth morphology 1 | 24
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
tremors 1 | 39

Disease

Carcinoma 64 | 11,493
glioblastoma 47 | 5,792
ovarian cancer 47 | 8,520
Breast cancer 41 | 3,578
Kidney cancer 40 | 2,613
lung cancer 38 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
pancreatic cancer 36 | 2,398
Astrocytoma, Pilocytic 35 | 3,081
ependymoma 35 | 4,679
lung adenocarcinoma 35 | 2,716
atypical teratoid / rhabdoid tumor 33 | 5,112
malignant mesothelioma 33 | 3,232
psoriasis 33 | 6,694
invasive ductal carcinoma 32 | 2,951
interstitial cystitis 31 | 2,312
lung carcinoma 31 | 2,843
osteosarcoma 31 | 7,950
non-small cell lung cancer 30 | 2,890
Duchenne muscular dystrophy 29 | 601
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
adult high grade glioma 28 | 3,801
medulloblastoma, large-cell 28 | 6,241
cystic fibrosis 27 | 1,696
gastric carcinoma 27 | 807
Autosomal recessive predisposition 26 | 1,442
ulcerative colitis 26 | 1,819
pituitary cancer 25 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
Cancer 23 | 2,499
ductal carcinoma in situ 22 | 1,745
juvenile dermatomyositis 22 | 1,187
nasopharyngeal carcinoma 21 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
primary pancreatic ductal adenocarcinoma 21 | 1,109
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
breast carcinoma 20 | 1,638
oligodendroglioma 20 | 2,850
Becker muscular dystrophy 19 | 191
primitive neuroectodermal tumor 19 | 3,035
esophageal adenocarcinoma 18 | 737
group 3 medulloblastoma 18 | 4,104
colon cancer 17 | 1,478
diabetes mellitus 17 | 1,728
limb girdle muscular dystrophy 2A 17 | 213
subependymal giant cell astrocytoma 17 | 2,287
Liver cancer 15 | 604
Myopia 15 | 176
adrenocortical carcinoma 15 | 1,428
tuberculosis 15 | 2,010
Liver Cirrhosis, Experimental 14 | 769
Melanoma 14 | 711
acute quadriplegic myopathy 14 | 1,158
Spontaneous abortion 13 | 113
active ulcerative colitis 13 | 764
interstitial lung disease 13 | 298
Kidney disease 12 | 430
Liver Cirrhosis 12 | 181
Schizophrenia 12 | 1,160
Skin cancer 12 | 469
astrocytoma 12 | 1,146
dermatomyositis 12 | 966
Acquired scoliosis 11 | 281
Curvature of spine 11 | 282
Hypertensive disease 11 | 292
urothelial carcinoma 11 | 318
Abortion, Spontaneous 10 | 109
Degenerative polyarthritis 10 | 115
Pick disease 10 | 1,894
Proteinuria 10 | 144
Short stature 10 | 531
pediatric high grade glioma 10 | 1,064
pterygium 10 | 76
Atopic dermatitis 9 | 952
Atrophic scar 9 | 18
Cataract 9 | 297
Nephrotic Syndrome 9 | 78
Prenatal onset 9 | 139
group 4 medulloblastoma 9 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 9 | 239
medulloblastoma 9 | 720
Atherosclerosis 8 | 291
Contracture 8 | 96
Contracture of joint 8 | 93
Ecchymosis 8 | 66
Endometriosis 8 | 540
Flexion contracture 8 | 93
Flexion contractures of joints 8 | 93
Increased tendency to bruise 8 | 66
Muscle hypotonia 8 | 571
Orbital separation excessive 8 | 244
Pectus excavatum 8 | 100
Round face 8 | 45
Round, full face 8 | 45
active Crohn's disease 8 | 922
cutaneous lupus erythematosus 8 | 1,057
primary Sjogren syndrome 8 | 735
Glaucoma 7 | 239
mucosa-associated lymphoid tissue lymphoma 7 | 484
nephrosclerosis 7 | 333

Tissue

Digestive Tract 69 | 17,369
Endocrine System 69 | 18,159
Female tissues 69 | 17,400
Male tissues 69 | 17,142
Skin and soft tissues 69 | 17,230
Blood and immune system 68 | 16,909
Liver and Pancreas 68 | 16,750
Respiratory system 68 | 16,393
Urinary Tract 67 | 16,678
Nervous System 65 | 16,725
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 4 | 4,145
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Collagen alpha-2(XI) chain COL11A2 Tbio Non-IDG -1.89476 73.6 143
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
CD81 antigen CD81 Tchem Non-IDG -2.77049 534.4 771
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Nidogen-1 NID1 Tbio Non-IDG -2.80605 647.4 267
Integrin alpha-8 ITGA8 Tbio Non-IDG -1.36974 22.0 145
Junctional adhesion molecule B JAM2 Tbio Non-IDG -1.72934 50.6 302
Collagen alpha-6(VI) chain COL6A6 Tdark Non-IDG -0.48745 3.28 27
Transforming growth factor-beta-induced protein ig-h3 TGFBI Tbio Non-IDG -2.63615 441.5 287