Development Level

Tbio 57 | 11,445
Tdark 12 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
male infertility 1 | 123
small superior vagus ganglion 1 | 74
thick ventricular wall 1 | 7
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Carcinoma 36 | 11,493
osteosarcoma 31 | 7,950
psoriasis 31 | 6,694
ovarian cancer 28 | 8,520
Cancer 26 | 2,499
Breast cancer 19 | 3,578
lung cancer 19 | 4,740
ependymoma 16 | 4,679
pancreatic cancer 16 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
non-small cell lung cancer 15 | 2,890
glioblastoma 14 | 5,792
interstitial cystitis 14 | 2,312
invasive ductal carcinoma 14 | 2,951
lung adenocarcinoma 14 | 2,716
medulloblastoma, large-cell 14 | 6,241
lung carcinoma 13 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
cystic fibrosis 11 | 1,696
Astrocytoma, Pilocytic 10 | 3,081
pituitary cancer 10 | 1,972
Prostatic Neoplasms 9 | 495
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
juvenile dermatomyositis 9 | 1,187
primary pancreatic ductal adenocarcinoma 9 | 1,109
tuberculosis 9 | 2,010
atypical teratoid / rhabdoid tumor 8 | 5,112
breast carcinoma 8 | 1,638
primary Sjogren syndrome 8 | 735
ulcerative colitis 8 | 1,819
Autosomal recessive predisposition 7 | 1,442
astrocytic glioma 7 | 2,597
cutaneous lupus erythematosus 7 | 1,057
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
spina bifida 7 | 1,074
subependymal giant cell astrocytoma 7 | 2,287
Rheumatoid arthritis 6 | 1,191
active ulcerative colitis 6 | 764
acute myeloid leukemia 6 | 783
ductal carcinoma in situ 6 | 1,745
malignant mesothelioma 6 | 3,232
Breast Neoplasms 5 | 445
Craniofacial Abnormalities 5 | 151
Ewing sarcoma 5 | 25
Mammary Neoplasms 5 | 425
Systemic lupus erythematosus 5 | 194
active Crohn's disease 5 | 922
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
pediatric high grade glioma 5 | 1,064
Atopic dermatitis 4 | 952
Blepharoptosis 4 | 231
Ewings sarcoma 4 | 8
Microphthalmia with limb anomalies 4 | 40
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Neoplastic Processes 4 | 10
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
sonic hedgehog group medulloblastoma 4 | 467
Acquired metabolic disease 3 | 336
Cataract 3 | 297
Cleft Palate 3 | 271
Coronary artery disease 3 | 268
Crohn's disease 3 | 321
Dental caries 3 | 164
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Leukemia, Myelocytic, Acute 3 | 120
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Orbital separation excessive 3 | 244
Parkinson's disease 3 | 392
Poor school performance 3 | 645
Prostate cancer 3 | 175
Strabismus 3 | 270
Syndactyly of fingers 3 | 48
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
atypical teratoid/rhabdoid tumor 3 | 357
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
tuberculosis and treatment for 6 months 3 | 409
urothelial carcinoma 3 | 318
Exophthalmos 2 | 112
Frontal bossing 2 | 157
Irido-corneo-trabecular dysgenesis (disorder) 2 | 10
Isolated growth hormone deficiency type II 2 | 4
Ptosis 2 | 48

Tissue

Endocrine System 67 | 18,159
Digestive Tract 64 | 17,369
Female tissues 62 | 17,400
Male tissues 61 | 17,142
Blood and immune system 60 | 16,909
Skin and soft tissues 60 | 17,230
Liver and Pancreas 58 | 16,750
Nervous System 57 | 16,725
Respiratory system 54 | 16,393
Urinary Tract 54 | 16,678
Cardiovascular System 47 | 15,192

Target Family

Transcription Factor 68 | 1,400
Non-IDG 2 | 12,091

PANTHER Protein Class (1)

winged helix/forkhead transcri... 70 | 70
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS domain-containing protein Elk-3 ELK3 Tbio Transcription Factor -0.17124 0.86 225
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
Forkhead box protein E3 FOXE3 Tbio Transcription Factor -1.53701 31.5 150
Forkhead box protein I3 FOXI3 Tdark Non-IDG 0.00000 105
Transcription factor Spi-B SPIB Tbio Transcription Factor -1.80629 65.0 120
Forkhead box protein D4-like 3 FOXD4L3 Tdark Transcription Factor 0.56 0.15 8
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
Forkhead box protein I2 FOXI2 Tbio Transcription Factor -0.77839 6.22 70
Transcriptional regulator ERG ERG Tchem Transcription Factor -1.19111 12.3 398
DNA-binding protein RFX6 RFX6 Tbio Transcription Factor -2.57722 368.8 44