Development Level

Tbio 117 | 11,445
Tchem 34 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 18 | 979
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 6 | 278
decreased bone mineral content 5 | 151
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
abnormal retina morphology 4 | 71
decreased lean body mass 4 | 135
embryonic lethality prior to o... 4 | 239
enlarged heart 4 | 210
increased bone mineral content 4 | 108
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased body length 3 | 101
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
edema 3 | 59
impaired glucose tolerance 3 | 75
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
microphthalmia 3 | 26
prenatal lethality prior to he... 3 | 87
abnormal behavior 2 | 298
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
cataract 2 | 92
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
hypoactivity 2 | 132
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased monocyte cell number 2 | 63
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased cardiac muscle contr... 1 | 11
decreased circulating creatine... 1 | 4
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
hydroencephaly 1 | 14
hydrometra 1 | 53
increased B cell number 1 | 9
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small spleen 1 | 19
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 113 | 11,493
ovarian cancer 95 | 8,520
osteosarcoma 82 | 7,950
psoriasis 75 | 6,694
Cancer 73 | 2,499
atypical teratoid / rhabdoid tumor 73 | 5,112
ependymoma 71 | 4,679
glioblastoma 71 | 5,792
medulloblastoma, large-cell 67 | 6,241
Breast cancer 53 | 3,578
lung cancer 45 | 4,740
adult high grade glioma 44 | 3,801
group 3 medulloblastoma 44 | 4,104
malignant mesothelioma 44 | 3,232
Astrocytoma, Pilocytic 40 | 3,081
interstitial cystitis 39 | 2,312
lung carcinoma 39 | 2,843
oligodendroglioma 39 | 2,850
invasive ductal carcinoma 37 | 2,951
primitive neuroectodermal tumor 36 | 3,035
breast carcinoma 34 | 1,638
pancreatic cancer 34 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
lung adenocarcinoma 33 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
non-small cell lung cancer 30 | 2,890
astrocytic glioma 29 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
subependymal giant cell astrocytoma 29 | 2,287
Kidney cancer 28 | 2,613
ductal carcinoma in situ 26 | 1,745
group 4 medulloblastoma 26 | 1,855
Schizophrenia 24 | 1,160
spina bifida 24 | 1,074
cystic fibrosis 23 | 1,696
astrocytoma 22 | 1,146
tuberculosis 22 | 2,010
colon cancer 21 | 1,478
pituitary cancer 21 | 1,972
Pick disease 20 | 1,894
Bipolar Disorder 19 | 666
Breast Neoplasms 19 | 445
pediatric high grade glioma 19 | 1,064
Multiple myeloma 18 | 1,332
Prostatic Neoplasms 18 | 495
juvenile dermatomyositis 18 | 1,187
Autosomal recessive predisposition 17 | 1,442
Rheumatoid arthritis 17 | 1,191
primary pancreatic ductal adenocarcinoma 17 | 1,109
ulcerative colitis 17 | 1,819
Cleft Palate 16 | 271
Stomach Neoplasms 16 | 300
acute quadriplegic myopathy 16 | 1,158
cutaneous lupus erythematosus 16 | 1,057
Orbital separation excessive 15 | 244
Osteoarthritis 15 | 184
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Liver Cirrhosis, Experimental 14 | 769
Lung Neoplasms 14 | 232
Mammary Neoplasms 14 | 425
Mental and motor retardation 14 | 608
Osteoporosis 14 | 363
medulloblastoma 14 | 720
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Colorectal Neoplasms 13 | 243
Intellectual disability 13 | 1,016
adrenocortical carcinoma 13 | 1,428
dermatomyositis 13 | 966
diabetes mellitus 13 | 1,728
Duchenne muscular dystrophy 12 | 601
Short stature 12 | 531
Vascular disease 12 | 319
Waldenstrons macroglobulinemia 12 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
gastric carcinoma 12 | 807
Colonic Neoplasms 11 | 142
Craniofacial Abnormalities 11 | 151
Hypertensive disease 11 | 292
Kidney disease 11 | 430
Obesity 11 | 678
Pulmonary Fibrosis 11 | 106
Cleft Lip 10 | 141
Cryptorchidism 10 | 296
Dull intelligence 10 | 645
Endometriosis 10 | 540
Epilepsy 10 | 792
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Muscle hypotonia 10 | 571
Neoplasm Metastasis 10 | 168
Ovarian Neoplasms 10 | 102
Parkinson's disease 10 | 392
Poor school performance 10 | 645
Ureteral obstruction 10 | 33
acute myeloid leukemia 10 | 783
esophageal adenocarcinoma 10 | 737
nasopharyngeal carcinoma 10 | 1,058
ovarian neoplasm 10 | 99

Tissue

Endocrine System 151 | 18,159
Female tissues 151 | 17,400
Digestive Tract 149 | 17,369
Male tissues 149 | 17,142
Nervous System 149 | 16,725
Skin and soft tissues 149 | 17,230
Blood and immune system 147 | 16,909
Urinary Tract 147 | 16,678
Liver and Pancreas 145 | 16,750
Respiratory system 141 | 16,393
Cardiovascular System 135 | 15,192

Target Family

Non-IDG 98 | 12,091
Transcription Factor 20 | 1,400
Enzyme 13 | 4,145
Kinase 13 | 634
GPCR 10 | 408

KEGG Pathway

Hippo signaling pathway 154 | 154
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
InaD-like protein PATJ Tbio Non-IDG -1.94236 82.0 103
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Growth/differentiation factor 7 GDF7 Tbio Non-IDG -1.56725 40.0 180
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
LIM domain-containing protein ajuba AJUBA Tbio Non-IDG -1.15520 13.9 65