Development Level

Tbio 83 | 11,651
Tdark 19 | 6,593
Tchem 11 | 1,388
Tclin 3 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased grip strength 116 | 116
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 79 | 11,493
ovarian cancer 70 | 8,520
medulloblastoma, large-cell 56 | 6,241
psoriasis 56 | 6,694
osteosarcoma 54 | 7,950
glioblastoma 53 | 5,792
atypical teratoid / rhabdoid tumor 50 | 5,112
ependymoma 39 | 4,679
group 3 medulloblastoma 38 | 4,104
adult high grade glioma 37 | 3,801
Astrocytoma, Pilocytic 34 | 3,081
lung cancer 33 | 4,740
primitive neuroectodermal tumor 32 | 3,035
Breast cancer 30 | 3,578
Kidney cancer 27 | 2,613
oligodendroglioma 26 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
malignant mesothelioma 25 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
invasive ductal carcinoma 24 | 2,951
lung adenocarcinoma 24 | 2,716
non-small cell lung cancer 23 | 2,890
subependymal giant cell astrocytoma 23 | 2,287
astrocytic glioma 22 | 2,597
lung carcinoma 22 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
pancreatic cancer 18 | 2,398
Autosomal recessive predisposition 17 | 1,442
Intellectual disability 17 | 1,016
Cancer 16 | 2,499
colon cancer 16 | 1,478
Pick disease 15 | 1,894
pituitary cancer 15 | 1,972
group 4 medulloblastoma 14 | 1,855
interstitial cystitis 14 | 2,312
Schizophrenia 13 | 1,160
breast carcinoma 13 | 1,638
tuberculosis 13 | 2,010
Bipolar Disorder 12 | 666
Epilepsy 12 | 792
ductal carcinoma in situ 12 | 1,745
pediatric high grade glioma 12 | 1,064
Atopic dermatitis 11 | 952
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Liver Cirrhosis, Experimental 10 | 769
astrocytoma 10 | 1,146
ulcerative colitis 10 | 1,819
adrenocortical carcinoma 9 | 1,428
cutaneous lupus erythematosus 9 | 1,057
juvenile dermatomyositis 9 | 1,187
Muscle hypotonia 8 | 571
Neurodegenerative disease 8 | 414
active ulcerative colitis 8 | 764
diabetes mellitus 8 | 1,728
Cognitive delay 7 | 608
Down syndrome 7 | 499
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Obesity 7 | 678
Poor school performance 7 | 645
Rheumatoid arthritis 7 | 1,191
esophageal adenocarcinoma 7 | 737
progressive supranuclear palsy 7 | 676
Autistic Disorder 6 | 364
Depressive disorder 6 | 409
Liver cancer 6 | 604
Motor delay 6 | 147
No development of motor milestones 6 | 147
Osteoporosis 6 | 363
Seizures 6 | 596
Waldenstrons macroglobulinemia 6 | 765
active Crohn's disease 6 | 922
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
cystic fibrosis 6 | 1,696
dermatomyositis 6 | 966
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Acquired scoliosis 5 | 281
Curvature of spine 5 | 282
Infantile onset 5 | 238
Multiple myeloma 5 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
fibroadenoma 5 | 559
gastric carcinoma 5 | 807
Alzheimer's disease 4 | 658
Autism spectrum disorder 4 | 101
Duchenne muscular dystrophy 4 | 601
Gait abnormality 4 | 135
Glaucoma 4 | 239
Prostatic Neoplasms 4 | 495
acute myeloid leukemia 4 | 783
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
urothelial carcinoma 4 | 318

Tissue

Endocrine System 113 | 18,159
Digestive Tract 112 | 17,369
Skin and soft tissues 109 | 17,230
Blood and immune system 108 | 16,909
Female tissues 108 | 17,400
Male tissues 108 | 17,142
Urinary Tract 108 | 16,678
Nervous System 107 | 16,725
Respiratory system 107 | 16,393
Liver and Pancreas 104 | 16,750
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 67 | 12,091
Enzyme 30 | 4,145
Transcription Factor 6 | 1,400
Ion Channel 3 | 344
Epigenetic 2 | 242
GPCR 2 | 408
Kinase 2 | 634
TF/Epigenetic 2 | 38
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine--tRNA ligase, cytoplasmic SARS Tbio Enzyme -2.37540 230.1 178
Lysophosphatidic acid receptor 4 LPAR4 Tchem GPCR -1.38205 22.6 190
Band 4.1-like protein 4A EPB41L4A Tdark Non-IDG -0.53048 3.08 100
Stromal cell-derived factor 2-like protein 1 SDF2L1 Tdark Non-IDG -0.57145 4.35 62
Carboxypeptidase N catalytic chain CPN1 Tchem Enzyme -2.71738 529.1 145
Protocadherin-9 PCDH9 Tbio Non-IDG -1.16138 14.2 55
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.70628 492.9 68
Prolyl 3-hydroxylase 1 P3H1 Tbio Enzyme -1.47252 31.3 199
Somatoliberin GHRH Tbio Non-IDG -3.26565 1918.4 202
Acyl-coenzyme A thioesterase 2, mitochondrial ACOT2 Tbio Enzyme -1.19955 15.4 93