Development Level

Tbio 30 | 11,445
Tchem 10 | 1,598
Tclin 7 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal heart morphology 2 | 162
decreased total body fat amoun... 2 | 207
increased heart weight 2 | 62
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small testis 1 | 58

Disease

Carcinoma 34 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 33 | 8,520
Cancer 32 | 2,499
atypical teratoid / rhabdoid tumor 24 | 5,112
glioblastoma 24 | 5,792
Breast cancer 23 | 3,578
medulloblastoma, large-cell 22 | 6,241
lung cancer 21 | 4,740
ependymoma 20 | 4,679
invasive ductal carcinoma 20 | 2,951
pancreatic cancer 19 | 2,398
malignant mesothelioma 18 | 3,232
cystic fibrosis 17 | 1,696
adult high grade glioma 16 | 3,801
lung carcinoma 16 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
psoriasis 15 | 6,694
non-small cell lung cancer 14 | 2,890
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 13 | 3,035
Astrocytoma, Pilocytic 12 | 3,081
breast carcinoma 12 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Kidney cancer 11 | 2,613
ductal carcinoma in situ 11 | 1,745
group 3 medulloblastoma 11 | 4,104
subependymal giant cell astrocytoma 11 | 2,287
pituitary cancer 10 | 1,972
primary pancreatic ductal adenocarcinoma 10 | 1,109
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
interstitial cystitis 9 | 2,312
Hypertension 8 | 396
Kidney disease 8 | 430
astrocytic glioma 8 | 2,597
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
diabetes mellitus 8 | 1,728
juvenile dermatomyositis 8 | 1,187
Coronary artery disease 7 | 268
Diabetic retinopathy 7 | 56
Heart disease 7 | 306
Myocardial Ischemia 7 | 169
Rheumatoid arthritis 7 | 1,191
cutaneous lupus erythematosus 7 | 1,057
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Cerebrovascular disease 6 | 238
Liver Cirrhosis, Experimental 6 | 769
Lymphedema 6 | 42
Schizophrenia 6 | 1,160
adrenocortical carcinoma 6 | 1,428
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
esophageal adenocarcinoma 6 | 737
Atherosclerosis 5 | 291
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Colorectal Neoplasms 5 | 243
Down syndrome 5 | 499
Glaucoma 5 | 239
Inflammation 5 | 120
Liver Cirrhosis 5 | 181
Mammary Neoplasms 5 | 425
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
Reperfusion Injury 5 | 86
Retinopathy of prematurity 5 | 22
Type 2 diabetes mellitus 5 | 272
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
gastric cancer 5 | 459
group 4 medulloblastoma 5 | 1,855
pancreatic carcinoma 5 | 562
Anemia 4 | 365
Arthritis, Rheumatoid 4 | 174
Duchenne muscular dystrophy 4 | 601
Hyperalgesia 4 | 83
Hypertensive disease 4 | 292
Hypoplastic mandible condyle 4 | 275
Impotence 4 | 42
Major Depressive Disorder 4 | 301
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Micrognathism 4 | 275
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Polycystic ovary syndrome 4 | 360
Skin cancer 4 | 469
Vascular disease 4 | 319
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
nasopharyngeal carcinoma 4 | 1,058
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Nervous System 46 | 16,725
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 25 | 12,091
Kinase 10 | 634
Transcription Factor 7 | 1,400
Enzyme 4 | 4,145
GPCR 1 | 408

GO Process

positive regulation of endothe... 47 | 47
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.23128 20.8 138
Rho-related GTP-binding protein RhoB RHOB Tbio Enzyme -2.41406 272.2 151
Protein C-ets-1 ETS1 Tbio Transcription Factor -2.89500 760.0 463
Annexin A3 ANXA3 Tbio Non-IDG -2.01462 104.6 354
Forkhead box protein P1 FOXP1 Tbio Transcription Factor -2.32310 210.5 533
Programmed cell death protein 6 PDCD6 Tbio Non-IDG -1.74455 59.1 235
Breast carcinoma-amplified sequence 3 BCAS3 Tbio Non-IDG -1.24719 16.2 149
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Serine/threonine-protein kinase D1 PRKD1 Tchem Kinase -2.88440 775.2 667