Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased total body fat amoun... 2 | 207
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal joint morphology 1 | 23
abnormal mandible morphology 1 | 2
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating potassiu... 1 | 20
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
Autosomal recessive predisposition 5 | 1,442
Muscle hypotonia 5 | 571
ovarian cancer 5 | 8,520
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Metabolic acidosis 3 | 90
astrocytic glioma 3 | 2,597
oligodendroglioma 3 | 2,850
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Chronic obstructive pulmonary disease 2 | 184
Delayed speech and language development 2 | 112
Dull intelligence 2 | 645
Dystonia 2 | 164
Dystonic disease 2 | 106
Electroencephalogram abnormal 2 | 101
Encephalopathies 2 | 43
Hypoglycemia 2 | 152
Intellectual disability 2 | 1,016
Language Delay 2 | 112
Little's Disease 2 | 14
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Movement Disorders 2 | 55
Orotic aciduria 2 | 18
Poor school performance 2 | 645
Seizures 2 | 596
Short stature 2 | 531
Speech Delay 2 | 112
Speech impairment 2 | 112
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of metabolism/homeostasis 1 | 134
Ankylosing spondylitis 1 | 140
Big calvaria 1 | 147
Citrullinemia 1 | 14
Coloboma 1 | 51
Corneal dystrophy 1 | 24
Cystinuria 1 | 18
Death in childhood 1 | 14
Delayed myelination 1 | 22
Dilation of lateral ventricles 1 | 4
Ectopia Lentis 1 | 17
Epilepsies, Myoclonic 1 | 32
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Facioscapulohumeral muscular dystrophy 1 | 26
Generalized myoclonic seizures 1 | 30
Hyperactive behavior 1 | 91
Hypertrophic Cardiomyopathy 1 | 117
Impotence 1 | 42
Increased head circumference 1 | 147
Increased serum lactate 1 | 60
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Irritation - emotion 1 | 68
Ketonemia 1 | 11
Ketosis 1 | 11
Leigh disease 1 | 100
Lethargy 1 | 77
Mild Mental Retardation 1 | 70
Muscle Rigidity 1 | 49
Myoclonic Epilepsies, Progressive 1 | 44
Nicotine dependence 1 | 54
Nonsyndromic deafness 1 | 142
Organic acidemia 1 | 4
Ornithine translocase deficiency 1 | 7
Osteoporosis 1 | 363
Pseudoxanthoma elasticum 1 | 18
Psoriatic arthritis 1 | 86
Respiratory Distress Syndrome 1 | 15
Respiratory distress 1 | 43
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Tonic - clonic seizures 1 | 44
Wernicke-Korsakoff syndrome 1 | 10
sarcoidosis 1 | 370

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Enzyme 11 | 4,145
Transporter 1 | 473

GO Process

lysine catabolic process 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dihydrolipoyl dehydrogenase, mitochondrial DLD Tbio Enzyme -2.58834 373.1 282
Peroxisomal sarcosine oxidase PIPOX Tbio Enzyme -2.20964 160.4 71