Development Level

Tdark 12 | 6,588
Tclin 8 | 613
Tchem 4 | 1,598

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

abnormal behavioral response t... 2 | 66
decreased total body fat amoun... 2 | 207
increased circulating sodium l... 2 | 71
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased anxiety-related resp... 1 | 12
decreased lean body mass 1 | 135
impaired pupillary reflex 1 | 26
increased circulating chloride... 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 21 | 11,493
Migraine 12 | 83
Schizophrenia 12 | 1,160
Major Depressive Disorder 9 | 301
Bipolar Disorder 8 | 666
Depressive disorder 8 | 409
Mood Disorders 8 | 184
Alzheimer's disease 6 | 658
Autistic Disorder 6 | 364
Mental Depression 6 | 333
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
Amnestic disorder 5 | 35
Cluster headache syndrome 5 | 8
Parkinson's disease 5 | 392
Substance abuse 5 | 59
malignant mesothelioma 5 | 3,232
obsessive-compulsive disorder 5 | 61
psoriasis 5 | 6,694
Attention deficit hyperactivity disorder 4 | 278
Dementia 4 | 175
Generalized anxiety disorder 4 | 29
Migraine Prevention 4 | 23
Obesity 4 | 678
Personality disorder 4 | 25
Unipolar Depression 4 | 250
Vascular headache 4 | 7
diabetes mellitus 4 | 1,728
medulloblastoma, large-cell 4 | 6,241
Bipolar affective disorder, current episode manic 3 | 13
Cluster Headache Prevention 3 | 6
Cocaine-Related Disorders 3 | 92
Hyperprolactinemia 3 | 27
Hypoactive sexual desire disorder 3 | 8
Irritable bowel syndrome 3 | 60
Kidney cancer 3 | 2,613
Memory Disorders 3 | 40
Mixed bipolar I disorder 3 | 9
Panic disorder 3 | 61
Premature ejaculation 3 | 16
Psychotic Disorders 3 | 151
Treatment-resistant schizophrenia 3 | 6
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Acromegaly 2 | 51
Agitation associated with Bipolar Mania 2 | 5
Agitation associated with Schizophrenia 2 | 5
Alcohol abuse 2 | 50
Amphetamine-Related Disorders 2 | 74
Astrocytoma, Pilocytic 2 | 3,081
Bipolar disorder in remission 2 | 19
Chronic thromboembolic pulmonary hypertension 2 | 4
Cocaine abuse 2 | 19
Constipation 2 | 181
Depression Treatment Adjunct 2 | 5
Diarrhea 2 | 253
Drug psychosis 2 | 7
Dyspepsia 2 | 33
Eating disorder 2 | 26
Epilepsy 2 | 792
Fever 2 | 138
Gastroparesis 2 | 22
Heart disease 2 | 306
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Hypertension 2 | 396
Hypotension 2 | 82
Infantile autism 2 | 4
Lack or loss of sexual desire 2 | 3
Learning Disorders 2 | 29
Migraine Disorders 2 | 76
Motion sickness 2 | 21
Pain 2 | 103
Pain agnosia 2 | 104
Postabortal Hemorrhage 2 | 3
Postpartum hemorrhage 2 | 6
Psychoses, Substance-Induced 2 | 17
Schizoaffective Disorder 2 | 55
Seasonal affective disorder 2 | 28
Seizures 2 | 596
Sexual dysfunction 2 | 9
Single major depressive episode 2 | 8
Sudden infant death syndrome 2 | 32
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
non diabetic and post-ischemic heart failure 2 | 200
ovarian cancer 2 | 8,520
post-traumatic stress disorder 2 | 40
pulmonary arterial hypertension 2 | 75
substance-related disorder 2 | 162
Anorexia 1 | 43
Anxiety Disorders 1 | 38
Chronic schizophrenia 1 | 16
Ileus 1 | 19
Nasal congestion 1 | 21
Nonorganic psychosis 1 | 84

Tissue

Endocrine System 13 | 18,159
Nervous System 12 | 16,725
Female tissues 11 | 17,400
Digestive Tract 10 | 17,369
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Blood and immune system 9 | 16,909
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

GPCR 12 | 408
oGPCR 12 | 421

GO Function

G-protein coupled serotonin re... 24 | 24
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Olfactory receptor 5T2 OR5T2 Tdark oGPCR 0.00000 27
Olfactory receptor 10H4 OR10H4 Tdark oGPCR 0.00000 82
Olfactory receptor 10H5 OR10H5 Tdark oGPCR 1.26 0.06 64
Olfactory receptor 6T1 OR6T1 Tdark oGPCR 0.00000 84
Olfactory receptor 11H4 OR11H4 Tdark oGPCR 0.00000 21
Olfactory receptor 11H7 OR11H7 Tdark oGPCR 0.00000 0
Olfactory receptor 10J5 OR10J5 Tdark oGPCR -0.17609 1.71 103
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259
5-hydroxytryptamine receptor 1D HTR1D Tclin GPCR -2.54328 350.8 140
5-hydroxytryptamine receptor 1B HTR1B Tclin GPCR -3.03042 1068.4 211