Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal retinal outer nuclear... 1 | 3
cataract 1 | 92
corneal opacity 1 | 32
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
irregularly shaped pupil 1 | 7
male infertility 1 | 123
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
ovarian cancer 15 | 8,520
osteosarcoma 13 | 7,950
group 3 medulloblastoma 7 | 4,104
psoriasis 7 | 6,694
Cancer 6 | 2,499
Intellectual disability 6 | 1,016
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
Muscle hypotonia 5 | 571
glioblastoma 5 | 5,792
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
subependymal giant cell astrocytoma 4 | 2,287
Acquired scoliosis 3 | 281
Adenoid Cystic Carcinoma 3 | 99
Breast Neoplasms 3 | 445
Carcinoma, Adenoid Cystic 3 | 99
Cataract 3 | 297
Constipation 3 | 181
Curvature of spine 3 | 282
Dull intelligence 3 | 645
Dyschezia 3 | 135
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Glaucoma 3 | 239
Lens Opacities 3 | 231
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurodegenerative disease 3 | 414
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Riley-Day syndrome 3 | 11
Schizophrenia 3 | 1,160
Short stature 3 | 531
Small head 3 | 374
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
dermatomyositis 3 | 966
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
Acquired flat foot 2 | 72
Agoraphobia 2 | 21
Angle class 2 malocclusion 2 | 57
Angle class 3 malocclusion 2 | 57
Auricular malformation 2 | 41
Bifid uterus 2 | 4
Broad thumbs 2 | 28
Bushy eyebrows 2 | 49
Carcinoma, Squamous Cell 2 | 110
Corneal abnormalities 2 | 6
Cornela disease 2 | 6
Decreased projection of maxilla 2 | 66
Defective enamel matrix 2 | 35
Deficiency of upper jaw bones 2 | 66
Dental Enamel Hypoplasia 2 | 43
Duane Retraction Syndrome 2 | 13
Dyslexia 2 | 43
Dysplasia of tooth enamel 2 | 35
Enophthalmos 2 | 75
Flared iliac wings 2 | 13
Flatfoot 2 | 73
Hirsutism 2 | 47
Hyperactive behavior 2 | 91
Hyperplasia of foramen magnum 2 | 6
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Inadequate arch length for tooth size 2 | 45
Increased circumference of foramen magnum 2 | 6
Increased diameter of foramen magnum 2 | 6
Joint laxity 2 | 54
Keloid 2 | 37
Koolen de Vries syndrome 2 | 18
Large foramen magnum 2 | 6
Laryngomalacia 2 | 14
Legg-Calve-Perthes disease 2 | 14
Low posterior hairline 2 | 52
Malocclusion 2 | 57
Maxillary retrognathia 2 | 66
Obesity, Abdominal 2 | 24
Phonophobia 2 | 11
Poor coordination 2 | 11
Recurrent upper respiratory tract infection 2 | 21
Retrusion of upper jaw bones 2 | 66
Self Mutilation 2 | 14
Simple ear 2 | 41
Sleep Apnea, Obstructive 2 | 10
Spina bifida occulta 2 | 19
Strawberry nevus of skin 2 | 10
Sunken eyes 2 | 63
Thin dental enamel 2 | 35
Tooth mass arch size discrepancy 2 | 45

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 10 | 12,091
Epigenetic 9 | 242
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38

GO Component

histone acetyltransferase comp... 21 | 21
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
KAT8 regulatory NSL complex subunit 1 KANSL1 Tbio Non-IDG -1.27149 17.9 36
WD repeat-containing protein 5 WDR5 Tchem Non-IDG -2.10077 115.4 299
Host cell factor 1 HCFC1 Tbio Non-IDG -2.56453 370.8 172
Elongator complex protein 4 ELP4 Tbio Non-IDG -1.27487 17.7 84
CREB-binding protein CREBBP Tchem Epigenetic -2.81657 471.6 449
Histone acetyltransferase KAT8 KAT8 Tchem Epigenetic -2.31028 198.4 195
Elongator complex protein 1 ELP1 Tbio Non-IDG -3.00934 962.5 215
Histone acetyltransferase KAT7 KAT7 Tbio TF/Epigenetic -1.68684 43.9 270
Elongator complex protein 3 ELP3 Tbio Epigenetic -1.75885 53.5 124