Development Level

Tbio 159 | 11,445
Tchem 22 | 1,598
Tclin 9 | 613
Tdark 7 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 22 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
abnormal behavior 5 | 298
abnormal embryo size 5 | 220
hypoactivity 4 | 132
preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
increased bone mineral content 3 | 108
increased or absent threshold ... 3 | 101
small superior vagus ganglion 3 | 74
abnormal craniofacial morpholo... 2 | 33
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal vibrissa morphology 2 | 25
decreased bone mineral density 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
limb grasping 2 | 41
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
anophthalmia 1 | 33
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality 1 | 28
syndactyly 1 | 23

Disease

ovarian cancer 118 | 8,520
Carcinoma 112 | 11,493
osteosarcoma 96 | 7,950
medulloblastoma, large-cell 85 | 6,241
glioblastoma 78 | 5,792
psoriasis 77 | 6,694
atypical teratoid / rhabdoid tumor 65 | 5,112
lung cancer 56 | 4,740
ependymoma 55 | 4,679
Astrocytoma, Pilocytic 42 | 3,081
non-small cell lung cancer 42 | 2,890
lung carcinoma 41 | 2,843
adult high grade glioma 40 | 3,801
malignant mesothelioma 40 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
invasive ductal carcinoma 37 | 2,951
tuberculosis 37 | 2,010
diabetes mellitus 36 | 1,728
Cancer 35 | 2,499
oligodendroglioma 35 | 2,850
Breast cancer 34 | 3,578
group 4 medulloblastoma 34 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
lung adenocarcinoma 34 | 2,716
pancreatic cancer 34 | 2,398
Kidney cancer 33 | 2,613
subependymal giant cell astrocytoma 33 | 2,287
astrocytic glioma 32 | 2,597
group 3 medulloblastoma 32 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,962
breast carcinoma 26 | 1,638
interstitial cystitis 26 | 2,312
Autosomal recessive predisposition 25 | 1,442
Multiple myeloma 24 | 1,332
juvenile dermatomyositis 24 | 1,187
primitive neuroectodermal tumor 24 | 3,035
cystic fibrosis 23 | 1,696
ductal carcinoma in situ 23 | 1,745
Pick disease 21 | 1,894
Rheumatoid arthritis 21 | 1,191
dermatomyositis 21 | 966
ulcerative colitis 21 | 1,819
adrenocortical carcinoma 20 | 1,428
astrocytoma 19 | 1,146
pediatric high grade glioma 19 | 1,064
primary pancreatic ductal adenocarcinoma 19 | 1,109
acute quadriplegic myopathy 18 | 1,158
Alzheimer's disease 17 | 658
Neurodegenerative disease 17 | 414
active Crohn's disease 17 | 922
cutaneous lupus erythematosus 17 | 1,057
pituitary cancer 17 | 1,972
Schizophrenia 15 | 1,160
esophageal adenocarcinoma 15 | 737
Asthma 14 | 385
non primary Sjogren syndrome sicca 14 | 891
primary Sjogren syndrome 14 | 735
Down syndrome 13 | 499
Waldenstrons macroglobulinemia 13 | 765
Obesity 12 | 678
aldosterone-producing adenoma 12 | 665
pancreatic carcinoma 12 | 562
Coronary artery disease 11 | 268
Diarrhea 11 | 253
Hypersensitivity reaction type II disease 11 | 253
Anemia 10 | 365
Duchenne muscular dystrophy 10 | 601
Liver Cirrhosis, Experimental 10 | 769
Melanoma 10 | 711
Multiple Sclerosis 10 | 540
Skin cancer 10 | 469
Vascular disease 10 | 319
acute myeloid leukemia 10 | 783
colon cancer 10 | 1,478
gastric carcinoma 10 | 807
mucosa-associated lymphoid tissue lymphoma 10 | 484
spina bifida 10 | 1,074
Heart disease 9 | 306
Influenza 9 | 142
Kidney disease 9 | 430
Osteopetrosis 9 | 43
Prostatic Neoplasms 9 | 495
active ulcerative colitis 9 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
fibroadenoma 9 | 559
progressive supranuclear palsy 9 | 676
Hypertension 8 | 396
Hypertensive disease 8 | 292
atypical teratoid/rhabdoid tumor 8 | 357
sarcoidosis 8 | 370
Arthritis 7 | 290
Failure to gain weight 7 | 365
Lung disease 7 | 142
Major Depressive Disorder 7 | 301
Pediatric failure to thrive 7 | 365
Short stature 7 | 531
Unipolar Depression 7 | 250
chronic rhinosinusitis 7 | 512
nasopharyngeal carcinoma 7 | 1,058

Tissue

Blood and immune system 196 | 16,909
Digestive Tract 195 | 17,369
Endocrine System 195 | 18,159
Female tissues 195 | 17,400
Male tissues 195 | 17,142
Respiratory system 195 | 16,393
Skin and soft tissues 195 | 17,230
Urinary Tract 195 | 16,678
Liver and Pancreas 194 | 16,750
Nervous System 190 | 16,725
Cardiovascular System 185 | 15,192

Target Family

Non-IDG 128 | 12,091
Enzyme 40 | 4,145
Kinase 15 | 634
Ion Channel 7 | 344
Transporter 5 | 473
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Component

endosome membrane 197 | 197
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/hydrogen exchanger 9B2 SLC9B2 Tbio Transporter -1.21956 18.8 126
Metalloreductase STEAP1 STEAP1 Tbio Enzyme -1.65454 46.2 322
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Endosomal/lysosomal potassium channel TMEM175 TMEM175 Tbio Non-IDG -0.65375 3.76 42
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Pleckstrin homology domain-containing family M member 2 PLEKHM2 Tbio Non-IDG -0.32760 3.56 65
H(+)/Cl(-) exchange transporter 4 CLCN4 Tchem Ion Channel -1.51383 32.8 132