Development Level

Tbio 80 | 11,445
Tchem 33 | 1,598
Tdark 10 | 6,588
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased caudal vertebrae num... 2 | 53
decreased circulating choleste... 2 | 93
short tibia 2 | 97
abnormal QT variability 1 | 10
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
cataract 1 | 92
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 93 | 8,520
Carcinoma 81 | 11,493
osteosarcoma 62 | 7,950
lung cancer 61 | 4,740
psoriasis 52 | 6,694
Cancer 47 | 2,499
glioblastoma 42 | 5,792
medulloblastoma, large-cell 38 | 6,241
atypical teratoid / rhabdoid tumor 36 | 5,112
tuberculosis 36 | 2,010
Breast cancer 33 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
pancreatic cancer 33 | 2,398
Multiple myeloma 32 | 1,332
non-small cell lung cancer 31 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
ependymoma 30 | 4,679
group 3 medulloblastoma 30 | 4,104
invasive ductal carcinoma 30 | 2,951
lung adenocarcinoma 29 | 2,716
Waldenstrons macroglobulinemia 28 | 765
subependymal giant cell astrocytoma 28 | 2,287
diabetes mellitus 27 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
malignant mesothelioma 27 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
adult high grade glioma 24 | 3,801
interstitial cystitis 24 | 2,312
Astrocytoma, Pilocytic 23 | 3,081
lung carcinoma 23 | 2,843
astrocytoma 22 | 1,146
Autosomal recessive predisposition 20 | 1,442
dermatomyositis 20 | 966
juvenile dermatomyositis 20 | 1,187
breast carcinoma 19 | 1,638
primary pancreatic ductal adenocarcinoma 19 | 1,109
cutaneous lupus erythematosus 18 | 1,057
oligodendroglioma 18 | 2,850
ulcerative colitis 18 | 1,819
Alzheimer's disease 17 | 658
acute quadriplegic myopathy 17 | 1,158
adrenocortical carcinoma 16 | 1,428
esophageal adenocarcinoma 16 | 737
Liver Cirrhosis, Experimental 15 | 769
mucosa-associated lymphoid tissue lymphoma 15 | 484
Vascular disease 14 | 319
astrocytic glioma 14 | 2,597
ductal carcinoma in situ 14 | 1,745
group 4 medulloblastoma 14 | 1,855
Kidney cancer 13 | 2,613
cystic fibrosis 13 | 1,696
primitive neuroectodermal tumor 13 | 3,035
Intellectual disability 12 | 1,016
Neoplasm Invasiveness 12 | 161
Pick disease 12 | 1,894
Rheumatoid arthritis 12 | 1,191
Schizophrenia 12 | 1,160
colon cancer 12 | 1,478
Arthritis 11 | 290
Osteoporosis 11 | 363
pituitary cancer 11 | 1,972
Atopic dermatitis 10 | 952
Breast Neoplasms 10 | 445
Dull intelligence 10 | 645
HIV Infections 10 | 102
Hepatomegaly 10 | 285
Low intelligence 10 | 645
Mammary Neoplasms 10 | 425
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
gastric carcinoma 10 | 807
Duchenne muscular dystrophy 9 | 601
Neoplasm Metastasis 9 | 168
Neurodegenerative disease 9 | 414
Obesity 9 | 678
Short stature 9 | 531
Splenomegaly 9 | 190
non primary Sjogren syndrome sicca 9 | 891
pancreatic carcinoma 9 | 562
primary Sjogren syndrome 9 | 735
Carcinoma, Hepatocellular 8 | 228
Liver carcinoma 8 | 240
Prostatic Neoplasms 8 | 495
Stomach Neoplasms 8 | 300
fibroadenoma 8 | 559
hepatocellular carcinoma 8 | 547
periodontitis 8 | 293
posterior fossa group A ependymoma 8 | 468
Asthma 7 | 385
Atherosclerosis 7 | 291
Bipolar Disorder 7 | 666
Carcinoma, Squamous Cell 7 | 110
Cardiomyopathies 7 | 110
Hypertension 7 | 396
Joint stiffness 7 | 84
Liver diseases 7 | 87
Squamous cell carcinoma 7 | 129
chronic lymphosyte leukemia 7 | 204
pediatric high grade glioma 7 | 1,064

Tissue

Blood and immune system 122 | 16,909
Digestive Tract 122 | 17,369
Endocrine System 122 | 18,159
Female tissues 122 | 17,400
Liver and Pancreas 122 | 16,750
Male tissues 122 | 17,142
Skin and soft tissues 122 | 17,230
Nervous System 121 | 16,725
Respiratory system 121 | 16,393
Urinary Tract 121 | 16,678
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 60 | 12,091
Enzyme 59 | 4,145
Kinase 9 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

ficolin-1-rich granule 129 | 129
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Cysteine-rich secretory protein LCCL domain-containing 2 CRISPLD2 Tbio Non-IDG -1.13460 15.4 88
Pyruvate kinase PKM PKM Tchem Kinase -3.15332 1424.2 749
Peptidyl-prolyl cis-trans isomerase A PPIA Tclin Enzyme -2.97822 870.7 436
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
T-complex protein 1 subunit theta CCT8 Tbio Non-IDG -1.49520 31.8 212
Protein yippee-like 5 YPEL5 Tbio Non-IDG -0.43996 3.19 89
Signal recognition particle 14 kDa protein SRP14 Tbio Non-IDG -1.25810 14.5 106
Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 Tchem Enzyme -3.19944 1567.0 498
Putative heat shock protein HSP 90-alpha A4 HSP90AA4P Tdark Non-IDG -3.31859 4681.5 0