Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal eye anterior chamber ... 1 | 9
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
increased bone mineral density 1 | 72
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Carcinoma 16 | 11,493
Cancer 13 | 2,499
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
Breast cancer 6 | 3,578
Schizophrenia 6 | 1,160
adrenocortical carcinoma 6 | 1,428
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
Pick disease 5 | 1,894
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
Liver cancer 4 | 604
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Carcinoma, Hepatocellular 3 | 228
Connective tissue disease 3 | 62
Crohn's disease 3 | 321
Endometrial cancer 3 | 311
Familial adenomatous polyposis 3 | 32
Hypoplastic mandible condyle 3 | 275
Increased hepatocellular carcinoma risk 3 | 27
Increased incidence of hepatocellular carcinoma 3 | 27
Intellectual disability 3 | 1,016
Large intestine cancer 3 | 126
Liver carcinoma 3 | 240
Lymphoma, Mantle-Cell 3 | 11
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 3 | 12
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Micronodular cirrhosis 3 | 12
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Somatic mutation 3 | 61
Subacute progressive viral hepatitis 3 | 9
breast carcinoma 3 | 1,638
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
osteoporosis-pseudoglioma syndrome 3 | 9
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
Abdominal Pain 2 | 98
Abnormality of retinal pigmentation 2 | 111
Adenoma 2 | 167
Autistic Disorder 2 | 364
Big calvaria 2 | 147
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Dementia 2 | 175
Headache 2 | 37
High forehead 2 | 102
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infantile onset 2 | 238
Liver neoplasms 2 | 130
Long philtrum 2 | 137
Lung Neoplasms 2 | 232
Malabsorption 2 | 82
Mesothelioma, Malignant 2 | 105
Muscular atrophy 2 | 71
Nerve Degeneration 2 | 121
Osteoarthritis 2 | 184
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Retinal pigment epithelial abnormality 2 | 111
Stomach Neoplasms 2 | 300
Tall forehead 2 | 102
Toxic encephalopathy 2 | 141
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Vascular disease 2 | 319
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Respiratory system 15 | 16,393

Target Family

Non-IDG 13 | 12,091
GPCR 2 | 408
Kinase 2 | 634
Enzyme 1 | 4,145

Compartment GO Term

Wnt signalosome 18 | 18
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Segment polarity protein dishevelled homolog DVL-2 DVL2 Tbio Non-IDG -1.87063 68.4 288
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169
Low-density lipoprotein receptor-related protein 6 LRP6 Tbio Non-IDG -2.44778 273.2 424
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
R-spondin-1 RSPO1 Tbio Non-IDG -2.26774 188.7 164
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Tchem Kinase -3.07199 1241.4 740
Protein Wnt-2 WNT2 Tbio Non-IDG -2.28986 167.8 174
Proto-oncogene Wnt-3 WNT3 Tchem Non-IDG -2.03358 99.5 291