Development Level

Tbio 228 | 11,445
Tdark 77 | 6,588
Tchem 24 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 27 | 979
preweaning lethality, incomple... 16 | 499
abnormal embryo size 11 | 220
embryonic lethality prior to t... 10 | 278
abnormal behavior 8 | 298
abnormal heart morphology 8 | 162
embryonic lethality prior to o... 8 | 239
decreased lean body mass 7 | 135
enlarged heart 7 | 210
embryonic growth retardation 6 | 106
increased circulating HDL chol... 6 | 80
increased mean corpuscular hem... 6 | 96
increased mean corpuscular vol... 6 | 92
decreased body weight 5 | 161
decreased bone mineral content 5 | 151
decreased hemoglobin content 5 | 68
short tibia 5 | 97
abnormal bone structure 4 | 187
decreased circulating chloride... 4 | 30
decreased circulating creatini... 4 | 39
decreased circulating glucose ... 4 | 126
decreased grip strength 4 | 116
decreased startle reflex 4 | 75
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
hypoactivity 4 | 132
impaired glucose tolerance 4 | 75
increased grip strength 4 | 41
increased hematocrit 4 | 46
increased lean body mass 4 | 172
male infertility 4 | 123
prenatal lethality prior to he... 4 | 87
abnormal bone mineralization 3 | 38
abnormal gait 3 | 69
anophthalmia 3 | 33
decreased basophil cell number 3 | 16
decreased blood urea nitrogen ... 3 | 51
decreased circulating iron lev... 3 | 32
decreased erythrocyte cell num... 3 | 62
decreased leukocyte cell numbe... 3 | 73
decreased red blood cell distr... 3 | 41
enlarged spleen 3 | 41
female infertility 3 | 60
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased circulating glucose ... 3 | 24
increased circulating triglyce... 3 | 42
increased heart weight 3 | 62
increased mean platelet volume 3 | 45
increased or absent threshold ... 3 | 101
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
thrombocytopenia 3 | 56
thrombocytosis 3 | 27
abnormal craniofacial morpholo... 2 | 33
abnormal heart left ventricle ... 2 | 16
abnormal joint morphology 2 | 23
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
abnormal seminal vesicle morph... 2 | 114
abnormal skin coloration 2 | 25
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal vocalization 2 | 21
brachydactyly 2 | 19
corneal opacity 2 | 32
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased heart left ventricle... 2 | 28
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
dilated heart left ventricle 2 | 11
edema 2 | 59
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 41
increased fasted circulating g... 2 | 76
increased neutrophil cell numb... 2 | 46
limb grasping 2 | 41
microphthalmia 2 | 26
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
prolonged QT interval 2 | 38
small adrenal glands 2 | 16
small spleen 2 | 19
small testis 2 | 58
syndactyly 2 | 23
vertebral fusion 2 | 23

Disease

Carcinoma 219 | 11,493
ovarian cancer 201 | 8,520
osteosarcoma 162 | 7,950
medulloblastoma, large-cell 142 | 6,241
glioblastoma 130 | 5,792
psoriasis 121 | 6,694
atypical teratoid / rhabdoid tumor 117 | 5,112
ependymoma 87 | 4,679
adult high grade glioma 85 | 3,801
lung cancer 85 | 4,740
group 3 medulloblastoma 78 | 4,104
Breast cancer 77 | 3,578
primitive neuroectodermal tumor 74 | 3,035
oligodendroglioma 71 | 2,850
Cancer 68 | 2,499
malignant mesothelioma 67 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 59 | 3,291
invasive ductal carcinoma 56 | 2,951
astrocytic glioma 55 | 2,597
Astrocytoma, Pilocytic 53 | 3,081
non-small cell lung cancer 53 | 2,890
Kidney cancer 49 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,989
Multiple myeloma 46 | 1,332
group 4 medulloblastoma 46 | 1,855
subependymal giant cell astrocytoma 46 | 2,287
pancreatic cancer 42 | 2,398
adrenocortical carcinoma 39 | 1,428
lung adenocarcinoma 39 | 2,716
breast carcinoma 38 | 1,638
tuberculosis 37 | 2,010
ductal carcinoma in situ 35 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
lung carcinoma 34 | 2,843
pituitary cancer 34 | 1,972
Pick disease 31 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
ulcerative colitis 31 | 1,819
interstitial cystitis 30 | 2,312
acute quadriplegic myopathy 28 | 1,158
Rheumatoid arthritis 27 | 1,191
Intellectual disability 25 | 1,016
colon cancer 24 | 1,478
juvenile dermatomyositis 24 | 1,187
diabetes mellitus 23 | 1,728
spina bifida 23 | 1,074
astrocytoma 22 | 1,146
dermatomyositis 21 | 966
pediatric high grade glioma 20 | 1,064
Autosomal recessive predisposition 18 | 1,442
Waldenstrons macroglobulinemia 18 | 765
medulloblastoma 18 | 720
nasopharyngeal carcinoma 18 | 1,058
Atopic dermatitis 17 | 952
Schizophrenia 17 | 1,160
aldosterone-producing adenoma 17 | 665
primary Sjogren syndrome 17 | 735
Dull intelligence 16 | 645
Epilepsy 16 | 792
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Parkinson's disease 16 | 392
Poor school performance 16 | 645
Endometriosis 15 | 540
Small head 14 | 374
cystic fibrosis 14 | 1,696
hepatocellular carcinoma 14 | 547
non primary Sjogren syndrome sicca 14 | 891
primary pancreatic ductal adenocarcinoma 14 | 1,109
tuberculosis and treatment for 6 months 14 | 409
Alzheimer's disease 13 | 658
Amyotrophic lateral sclerosis 13 | 451
Seizures 13 | 596
Short stature 13 | 531
posterior fossa group A ependymoma 13 | 468
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Bipolar Disorder 11 | 666
Breast Neoplasms 11 | 445
Liver cancer 11 | 604
Mammary Neoplasms 11 | 425
Prostatic Neoplasms 11 | 495
active Crohn's disease 11 | 922
cutaneous lupus erythematosus 11 | 1,057
gastric carcinoma 11 | 807
Acquired metabolic disease 10 | 336
Cryptorchidism 10 | 296
acute myeloid leukemia 10 | 783
gastric cancer 10 | 459
sonic hedgehog group medulloblastoma 10 | 467
Glaucoma 9 | 239
esophageal adenocarcinoma 9 | 737
Cataract 8 | 297
Cleft Palate 8 | 271
Hypertensive disease 8 | 292
Lens Opacities 8 | 231
Muscle hypotonia 8 | 571
Nystagmus 8 | 317

Tissue

Endocrine System 332 | 18,159
Male tissues 328 | 17,142
Digestive Tract 327 | 17,369
Skin and soft tissues 327 | 17,230
Female tissues 324 | 17,400
Nervous System 324 | 16,725
Blood and immune system 323 | 16,909
Liver and Pancreas 319 | 16,750
Urinary Tract 319 | 16,678
Respiratory system 318 | 16,393
Cardiovascular System 311 | 15,192

Target Family

Non-IDG 246 | 12,091
Enzyme 61 | 4,145
Kinase 9 | 634
Epigenetic 8 | 242
Transcription Factor 7 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48

Compartment GO Term

Ubiquitin ligase complex 333 | 333
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
DCN1-like protein 5 DCUN1D5 Tdark Non-IDG -0.30103 2.00 14
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
F-box/LRR-repeat protein 2 FBXL2 Tbio Non-IDG -0.89339 8.63 129
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
RING finger protein 222 RNF222 Tdark Non-IDG 0.00000 4
Kelch repeat and BTB domain-containing protein 6 KBTBD6 Tdark Non-IDG 0.85 0.22 40
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208