Development Level

Tbio 19 | 11,445
Tdark 10 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

embryonic lethality prior to o... 5 | 239
preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased fluid intake 1 | 3
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
increased body length 1 | 32
increased body weight 1 | 25
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 22 | 11,493
ovarian cancer 21 | 8,520
osteosarcoma 13 | 7,950
lung cancer 12 | 4,740
Cancer 11 | 2,499
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
group 3 medulloblastoma 9 | 4,104
Breast cancer 8 | 3,578
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
ependymoma 7 | 4,679
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
Intellectual disability 6 | 1,016
Multiple myeloma 6 | 1,332
diabetes mellitus 6 | 1,728
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Liver cancer 4 | 604
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Alpha thalassemia 3 | 10
Alzheimer's disease 3 | 658
Cockayne syndrome 3 | 60
Endometriosis 3 | 540
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Macrostomia 3 | 72
Pick disease 3 | 1,894
Schimke immuno-osseous dysplasia 3 | 8
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
spina bifida 3 | 1,074
Adenoid Cystic Carcinoma 2 | 99
Astrocytoma, Pilocytic 2 | 3,081
Ataxia telangiectasia 2 | 34
Atopic dermatitis 2 | 952
Brachydactyly 2 | 156
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Cleft Palate 2 | 271
Coffin-Siris syndrome 2 | 17
Cognitive delay 2 | 608
Connective tissue disease 2 | 62
Cryptorchidism 2 | 296
Dental caries 2 | 164
Dull intelligence 2 | 645
Enamel erosion 2 | 19
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Full lower lip 2 | 64
Generalized hirsutism 2 | 36
Gingivitis 2 | 29
Global developmental delay 2 | 608
Joint hyperflexibility 2 | 78
Long eyelashes 2 | 37
Low intelligence 2 | 645
Lupus erythematosus 2 | 57
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Nasal bridge wide 2 | 236
Poor school performance 2 | 645
Prominent lower lip 2 | 64
Retinitis pigmentosa 20 2 | 5
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Short stature 2 | 531
Small head 2 | 374
Spondyloepiphyseal dysplasia with congenital joint dislocations 2 | 13
Thyroiditis 2 | 29
Triangular face 2 | 58
Williams-Beuren syndrome 2 | 50
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162

Tissue

Cardiovascular System 33 | 15,192
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Liver and Pancreas 32 | 16,750
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678

Target Family

Non-IDG 25 | 12,091
Epigenetic 4 | 242
Enzyme 3 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

Ino80 complex 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Chromodomain-helicase-DNA-binding protein 1 CHD1 Tbio Epigenetic -2.14472 148.3 122
INO80 complex subunit D INO80D Tdark Non-IDG -0.39378 1.30 38
Actin-related protein 5 ACTR5 Tbio Non-IDG 0.08 0.95 92
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40659 32.1 99
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
Probable global transcription activator SNF2L2 SMARCA2 Tchem Epigenetic -2.57435 345.3 153