Development Level

Tbio 122 | 11,651
Tclin 29 | 612
Tchem 26 | 1,388
Tdark 12 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal behavior 5 | 298
decreased total body fat amoun... 4 | 207
preweaning lethality, complete... 4 | 979
decreased vertical activity 3 | 208
improved glucose tolerance 3 | 79
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
enlarged spleen 2 | 41
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased circulating thyroxin... 2 | 7
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal pancreas morphology 1 | 13
abnormal rib morphology 1 | 10
abnormal tail movements 1 | 12
abnormal urination 1 | 1
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased B cell number 1 | 9
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 131 | 11,493
osteosarcoma 113 | 7,950
ovarian cancer 113 | 8,519
glioblastoma 100 | 5,792
psoriasis 93 | 6,694
medulloblastoma, large-cell 83 | 6,241
Cancer 82 | 2,499
lung cancer 77 | 4,740
lung carcinoma 70 | 2,843
atypical teratoid / rhabdoid tumor 66 | 5,112
interstitial cystitis 62 | 2,312
ependymoma 59 | 4,679
malignant mesothelioma 57 | 3,232
Astrocytoma, Pilocytic 56 | 3,081
Breast cancer 56 | 3,577
invasive ductal carcinoma 53 | 2,950
adult high grade glioma 52 | 3,801
non-small cell lung cancer 50 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
group 3 medulloblastoma 47 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,290
subependymal giant cell astrocytoma 47 | 2,287
ulcerative colitis 47 | 1,819
tuberculosis 45 | 2,010
pancreatic cancer 44 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,954
diabetes mellitus 41 | 1,728
oligodendroglioma 39 | 2,850
lung adenocarcinoma 38 | 2,716
Rheumatoid arthritis 35 | 1,191
cutaneous lupus erythematosus 35 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
primary Sjogren syndrome 33 | 735
astrocytic glioma 31 | 2,597
juvenile dermatomyositis 31 | 1,187
Pick disease 30 | 1,894
pituitary cancer 30 | 1,972
Kidney cancer 29 | 2,613
Multiple Sclerosis 29 | 540
Autosomal recessive predisposition 28 | 1,442
primitive neuroectodermal tumor 28 | 3,035
Multiple myeloma 27 | 1,332
ductal carcinoma in situ 27 | 1,744
breast carcinoma 26 | 1,637
dermatomyositis 26 | 966
group 4 medulloblastoma 26 | 1,855
cystic fibrosis 25 | 1,695
Duchenne muscular dystrophy 24 | 601
astrocytoma 24 | 1,146
Hypersensitivity reaction type II disease 22 | 253
Schizophrenia 22 | 1,160
acute quadriplegic myopathy 22 | 1,158
adrenocortical carcinoma 22 | 1,428
esophageal adenocarcinoma 22 | 737
Down syndrome 21 | 499
mucosa-associated lymphoid tissue lymphoma 21 | 484
primary pancreatic ductal adenocarcinoma 21 | 1,108
Liver Cirrhosis, Experimental 20 | 769
gastric carcinoma 20 | 807
nasopharyngeal carcinoma 20 | 1,058
pediatric high grade glioma 20 | 1,064
Alzheimer's disease 19 | 658
Asthma 17 | 385
Atopic dermatitis 17 | 952
Waldenstrons macroglobulinemia 17 | 765
active Crohn's disease 16 | 922
active ulcerative colitis 16 | 764
Atherosclerosis 15 | 291
colon cancer 15 | 1,478
Anemia 14 | 365
Kidney disease 13 | 430
acute myeloid leukemia 13 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
pancreatic carcinoma 13 | 562
sarcoidosis 13 | 370
Allergic hypersensitivity disease 12 | 126
Bipolar Disorder 12 | 666
Human immunodeficiency virus infectious disease 12 | 138
Hypertension 12 | 396
Lymphoproliferative syndrome 12 | 58
periodontitis 12 | 293
Breast Neoplasms 11 | 445
Hepatitis B 11 | 108
Mammary Neoplasms 11 | 425
Obesity 11 | 678
Vascular disease 11 | 319
spina bifida 11 | 1,074
Chronic Lymphocytic Leukemia 10 | 262
Dermatitis 10 | 157
Endometriosis 10 | 540
Inflammatory bowel disease 10 | 151
Neurodegenerative disease 10 | 414
Systemic lupus erythematosus 10 | 194
head and neck cancer and chronic obstructive pulmonary disease 10 | 239
non primary Sjogren syndrome sicca 10 | 891
Arthritis 9 | 290
Intellectual disability 9 | 1,016
Splenomegaly 9 | 190
hepatocellular carcinoma 9 | 547
nephrosclerosis 9 | 333

Tissue

Blood and immune system 183 | 16,909
Endocrine System 183 | 18,159
Female tissues 183 | 17,400
Respiratory system 183 | 16,393
Urinary Tract 183 | 16,678
Digestive Tract 182 | 17,369
Liver and Pancreas 182 | 16,750
Male tissues 182 | 17,142
Skin and soft tissues 182 | 17,230
Nervous System 179 | 16,725
Cardiovascular System 174 | 15,192

Target Family

Non-IDG 133 | 12,091
Transporter 17 | 473
Enzyme 16 | 4,145
GPCR 10 | 408
Kinase 8 | 634
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

MedB1 189 | 189
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Interleukin-10 receptor subunit beta IL10RB Tbio Non-IDG -1.84842 57.3 222
Solute carrier family 12 member 9 SLC12A9 Tdark Transporter -0.45387 3.01 13
Tumor necrosis factor receptor superfamily member 8 TNFRSF8 Tclin Non-IDG -3.45141 2817.5 1193
Ras-related protein Rab-5C RAB5C Tbio Enzyme -1.20325 12.9 155
Anoctamin-6 ANO6 Tbio Ion Channel -2.50568 319.2 90
Cell adhesion molecule 1 CADM1 Tbio Non-IDG -2.77749 549.7 479
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.87615 736.2 222