Development Level

Tbio 1,366 | 11,178
Tchem 306 | 1,885
Tdark 174 | 6,569
Tclin 71 | 612

Collection

Kinase: IDG Consortium (Target... 11 | 125
Ion Channel: IDG Consortium (T... 6 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 157 | 979
preweaning lethality, incomple... 70 | 499
embryonic lethality prior to t... 54 | 278
embryonic lethality prior to o... 52 | 239
abnormal embryo size 33 | 220
decreased total body fat amoun... 28 | 207
abnormal behavior 24 | 298
decreased body weight 23 | 161
abnormal bone structure 22 | 187
increased lean body mass 20 | 172
increased startle reflex 20 | 112
hypoactivity 18 | 132
embryonic growth retardation 17 | 106
enlarged heart 17 | 210
abnormal seminal vesicle morph... 16 | 114
decreased bone mineral content 16 | 151
increased grip strength 16 | 41
hyperactivity 15 | 148
increased circulating alkaline... 15 | 122
increased mean corpuscular hem... 15 | 96
increased total body fat amoun... 15 | 134
decreased bone mineral density 14 | 126
decreased vertical activity 14 | 208
decreased circulating glucose ... 13 | 126
increased circulating HDL chol... 13 | 80
male infertility 12 | 123
abnormal heart morphology 11 | 162
abnormal retina morphology 11 | 71
decreased erythrocyte cell num... 11 | 62
decreased prepulse inhibition 11 | 82
decreased startle reflex 11 | 75
pallor 11 | 34
prenatal lethality prior to he... 11 | 87
decreased circulating alanine ... 10 | 47
decreased hemoglobin content 10 | 68
decreased mean corpuscular vol... 10 | 79
impaired glucose tolerance 10 | 75
increased bone mineral density 10 | 72
increased circulating choleste... 10 | 66
increased or absent threshold ... 10 | 101
small testis 10 | 58
abnormal behavioral response t... 9 | 66
decreased circulating insulin ... 9 | 76
decreased circulating triglyce... 9 | 79
decreased grip strength 9 | 116
decreased lean body mass 9 | 135
decreased leukocyte cell numbe... 9 | 73
decreased lymphocyte cell numb... 9 | 83
improved glucose tolerance 9 | 79
increased fasted circulating g... 9 | 76
increased mean corpuscular vol... 9 | 92
abnormal eye morphology 8 | 68
abnormal sleep behavior 8 | 70
decreased body length 8 | 101
decreased caudal vertebrae num... 8 | 53
decreased circulating aspartat... 8 | 34
decreased fasted circulating g... 8 | 65
decreased hematocrit 8 | 46
increased bone mineral content 8 | 108
increased monocyte cell number 8 | 63
abnormal gait 7 | 69
abnormal lens morphology 7 | 81
abnormal neural tube closure 7 | 46
abnormal skin morphology 7 | 50
cataract 7 | 92
decreased circulating HDL chol... 7 | 68
decreased mean corpuscular hem... 7 | 50
edema 7 | 59
enlarged lymph nodes 7 | 37
increased circulating calcium ... 7 | 34
increased circulating iron lev... 7 | 30
increased heart weight 7 | 62
pale yolk sac 7 | 25
short tibia 7 | 97
thrombocytopenia 7 | 56
abnormal embryo turning 6 | 31
abnormal epididymis morphology 6 | 42
abnormal lung morphology 6 | 26
decreased circulating alkaline... 6 | 46
decreased circulating calcium ... 6 | 36
decreased circulating chloride... 6 | 30
decreased circulating serum al... 6 | 82
decreased circulating sodium l... 6 | 22
decreased red blood cell distr... 6 | 41
hydrometra 6 | 53
increased circulating total pr... 6 | 28
increased mean platelet volume 6 | 45
increased neutrophil cell numb... 6 | 46
limb grasping 6 | 41
small superior vagus ganglion 6 | 74
abnormal coat-hair pigmentatio... 5 | 64
decreased circulating choleste... 5 | 93
enlarged spleen 5 | 41
increased body weight 5 | 25
increased circulating amylase ... 5 | 25
increased circulating phosphat... 5 | 26
increased mean corpuscular hem... 5 | 36
increased prepulse inhibition 5 | 32
prolonged QT interval 5 | 38
thrombocytosis 5 | 27

Disease

Carcinoma 1,300 | 11,192
ovarian cancer 1,159 | 8,297
osteosarcoma 970 | 7,766
medulloblastoma, large-cell 785 | 6,086
glioblastoma 774 | 5,635
psoriasis 774 | 6,514
lung cancer 685 | 4,607
atypical teratoid / rhabdoid tumor 621 | 4,971
ependymoma 548 | 4,559
Breast cancer 452 | 3,469
group 3 medulloblastoma 444 | 4,002
intraductal papillary-mucinous neoplasm (IPMN) 436 | 3,204
adult high grade glioma 433 | 3,701
malignant mesothelioma 431 | 3,135
Astrocytoma, Pilocytic 387 | 3,006
invasive ductal carcinoma 385 | 2,867
non-small cell lung cancer 382 | 2,799
Cancer 377 | 2,388
intraductal papillary-mucinous carcinoma (IPMC) 374 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 346 | 2,872
oligodendroglioma 344 | 2,768
lung adenocarcinoma 343 | 2,627
Kidney cancer 337 | 2,548
primitive neuroectodermal tumor 328 | 2,957
pancreatic cancer 320 | 2,322
lung carcinoma 303 | 2,755
pancreatic ductal adenocarcinoma liver metastasis 298 | 1,911
astrocytic glioma 297 | 2,530
subependymal giant cell astrocytoma 294 | 2,230
Multiple myeloma 291 | 1,296
diabetes mellitus 287 | 1,683
interstitial cystitis 259 | 2,237
tuberculosis 250 | 1,963
Pick disease 243 | 1,856
ulcerative colitis 236 | 1,765
group 4 medulloblastoma 233 | 1,806
Autosomal recessive predisposition 229 | 1,407
acute quadriplegic myopathy 226 | 1,133
astrocytoma 218 | 1,113
pituitary cancer 207 | 1,915
ductal carcinoma in situ 205 | 1,686
juvenile dermatomyositis 204 | 1,147
Rheumatoid arthritis 201 | 1,156
colon cancer 200 | 1,428
breast carcinoma 199 | 1,589
dermatomyositis 181 | 941
cystic fibrosis 171 | 1,629
adrenocortical carcinoma 169 | 1,385
Waldenstrons macroglobulinemia 166 | 742
pediatric high grade glioma 158 | 1,035
Intellectual disability 157 | 998
Schizophrenia 154 | 1,136
cutaneous lupus erythematosus 146 | 1,016
primary pancreatic ductal adenocarcinoma 143 | 1,071
spina bifida 142 | 1,053
Epilepsy 137 | 775
active Crohn's disease 136 | 882
Liver Cirrhosis, Experimental 118 | 733
non primary Sjogren syndrome sicca 115 | 861
Seizures 114 | 584
Alzheimer's disease 113 | 640
Cognitive delay 111 | 596
Global developmental delay 111 | 596
Mental and motor retardation 111 | 596
Atopic dermatitis 106 | 915
Dull intelligence 104 | 634
Low intelligence 104 | 634
Mental Retardation 104 | 634
Mental deficiency 104 | 634
Poor school performance 104 | 634
nasopharyngeal carcinoma 104 | 1,024
Obesity 103 | 655
primary Sjogren syndrome 102 | 710
esophageal adenocarcinoma 101 | 696
Muscle hypotonia 98 | 562
Short stature 98 | 514
active ulcerative colitis 97 | 736
Duchenne muscular dystrophy 95 | 587
acute myeloid leukemia 93 | 760
gastric carcinoma 93 | 781
Bipolar Disorder 92 | 646
aldosterone-producing adenoma 92 | 646
Liver cancer 89 | 589
progressive supranuclear palsy 86 | 656
medulloblastoma 84 | 702
Down syndrome 80 | 480
Neurodegenerative disease 80 | 402
Endometriosis 79 | 521
Small head 79 | 366
Prostatic Neoplasms 77 | 472
autosomal dominant Emery-Dreifuss muscular dystrophy 76 | 492
Breast Neoplasms 73 | 423
Mammary Neoplasms 71 | 403
Depressive disorder 69 | 401
Failure to gain weight 69 | 359
Pediatric failure to thrive 69 | 359
Melanoma 68 | 689
Amyotrophic lateral sclerosis 67 | 437
pancreatic carcinoma 65 | 555
Nystagmus 63 | 309

Tissue

Endocrine System 1,879 | 18,159
Digestive Tract 1,875 | 17,369
Female tissues 1,871 | 17,400
Skin and soft tissues 1,868 | 17,230
Blood and immune system 1,857 | 16,909
Nervous System 1,852 | 16,725
Urinary Tract 1,852 | 16,678
Liver and Pancreas 1,851 | 16,750
Male tissues 1,851 | 17,142
Respiratory system 1,831 | 16,393
Cardiovascular System 1,792 | 15,192

Target Family

Non-IDG 1,099 | 12,091
Enzyme 542 | 4,145
Transporter 114 | 473
Kinase 83 | 634
Ion Channel 28 | 344
Transcription Factor 23 | 1,400
GPCR 15 | 408
Epigenetic 11 | 242
Nuclear Receptor 2 | 48

GO Component

membrane 1,917 | 1,917
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability